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Enhanced disinfection leads to reduction of microbial contamination and a decrease in patient colonization and infection

Published online by Cambridge University Press:  31 July 2018

William A. Rutala ,
Hajime Kanamori ,
Maria F. Gergen ,
Lauren P. Knelson ,
Emily E. Sickbert-Bennett ,
Luke F. Chen ,
Deverick J. Anderson ,
Daniel J. Sexton ,
David J. Weber  and
and the CDC Prevention Epicenters Program
William A. Rutala*
Affiliation:
Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, North Carolina, United States Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, North Carolina, United States
Hajime Kanamori
Affiliation:
Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, North Carolina, United States Infection Control and Laboratory Diagnostics, Internal Medicine, Tohoku University, Sendai, Japan
Maria F. Gergen
Affiliation:
Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, North Carolina, United States
Lauren P. Knelson
Affiliation:
Division of Infectious Diseases, Duke Center for Antimicrobial Stewardship and Infection Prevention, Duke University Medical Center, Durham, North Carolina, United States
Emily E. Sickbert-Bennett
Affiliation:
Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, North Carolina, United States Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, North Carolina, United States
Luke F. Chen
Affiliation:
Division of Infectious Diseases, Duke Center for Antimicrobial Stewardship and Infection Prevention, Duke University Medical Center, Durham, North Carolina, United States
Deverick J. Anderson
Affiliation:
Division of Infectious Diseases, Duke Center for Antimicrobial Stewardship and Infection Prevention, Duke University Medical Center, Durham, North Carolina, United States
Daniel J. Sexton
Affiliation:
Division of Infectious Diseases, Duke Center for Antimicrobial Stewardship and Infection Prevention, Duke University Medical Center, Durham, North Carolina, United States
David J. Weber
Affiliation:
Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, North Carolina, United States Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, North Carolina, United States
*
Author for correspondence: William A. Rutala, PhD, MPH, CIC, Division of Infectious Diseases, UNC School of Medicine, Bioinformatics Building, CB#7030, 130 Mason Farm Road, Chapel Hill, NC 27514-7030. E-mail: brutala@med.unc.edu
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Abstract

In this prospective study, we monitored 4 epidemiologically important pathogens (EIPs): methicillin-resistane Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), Clostridium difficile, and multidrug-resistant (MDR) Acinetobacter to assess the effectiveness of 3 enhanced disinfection strategies for terminal room disinfection against standard practice. Our data demonstrated that a decrease in room contamination with EIPs of 94% was associated with a 35% decrease in subsequent patient colonization and/or infection.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 39 , Issue 9 , September 2018 , pp. 1118 - 1121
Copyright
© 2018 by The Society for Healthcare Epidemiology of America. All rights reserved. 

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Footnotes

Cite this article: Rutala WA, et al. (2018). Enhanced disinfection leads to reduction of microbial contamination and a decrease in patient colonization and infection. Infection Control & Hospital Epidemiology. 2018, 39, 1118–1121. doi: 10.1017/ice.2018.165

References

1. Otter, JA, Yezli, S, Salkeld, JA, French, GL. Evidence that contaminated surfaces contribute to the transmission of hospital pathogens and an overview of strategies to address contaminated surfaces in hospital settings. Am J Infect Control 2013;41:S6–S11.Google Scholar
2. Donskey, CJ. Does improving surface cleaning and disinfection reduce health care-associated infections? Am J Infect Control 2013;41:S12–S19.Google Scholar
3. Rutala, WA, Weber, DJ. Monitoring and improving the effectiveness of surface cleaning and disinfection. Am J Infect Control 2016;44:e69–e76.Google Scholar
4. Carling, P. Methods for assessing the adequacy of practice and improving room disinfection. Am J Infect Control 2013;41:S20–S25.Google Scholar
5. Weber, DJ, Rutala, WA, Anderson, DJ, Chen, LF, Sickbert-Bennett, EE, Boyce, JM. Effectiveness of UV devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials. Am J Infect Control 2016;44:e77–e84.Google Scholar
6. Anderson, DJ, Chen, LF, Weber, DJ, et al. The benefits of enhanced terminal room (BETR) disinfection study: a prospective, cluster randomized, multicenter, crossover study to evaluate the impact of enhanced terminal room disinfection on acquisition and infection caused by multidrug-resistant organisms. Lancet 2017;389:805–814.Google Scholar
7. Magill, SS, Edwards, JR, Bamberg, W, Beldavs, ZG, Dumyati, G, et al. Multistate point-prevalence survey of healthcare-associated infections. New Engl J Med 2014;370:1198–1208.Google Scholar
8. Chen, LF, Knelson, L, Gergen, M, et al. A prospective study of transmission of multi-drug resistant organism (MDRO) between environmental sites and hospital patients-The TransFER study. Submitted for publication.Google Scholar
9. Huslage, K, Rutala, WA, Gergen, MF, Sickbert-Bennett, EE, Weber, DJ. Microbial assessment of high-, medium-, and low-touch hospital room surfaces. Infect Control Hosp Epidemiol 2013;34:211–212.Google Scholar