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Effect of testing methods on incidence of Clostridioides difficile infection rates in Veterans’ Affairs medical centers

Published online by Cambridge University Press:  13 November 2020

Brian P. McCauley*
Affiliation:
National Infectious Diseases Service, Specialty Care Services, Veterans’ Affairs Central Office, Washington, DC MRSA/MDRO Prevention Office, National Infectious Diseases Service, Specialty Care Services, Veterans’ Affairs Central Office, Washington, DC
Martin E. Evans
Affiliation:
MRSA/MDRO Prevention Office, National Infectious Diseases Service, Specialty Care Services, Veterans’ Affairs Central Office, Washington, DC Lexington Veterans’ Affairs Medical Center, Lexington, Kentucky Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky School of Medicine, Lexington, Kentucky
Loretta A. Simbartl
Affiliation:
National Infectious Diseases Service, Specialty Care Services, Veterans’ Affairs Central Office, Washington, DC
Shantini D. Gamage
Affiliation:
National Infectious Diseases Service, Specialty Care Services, Veterans’ Affairs Central Office, Washington, DC Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio
Stephen M. Kralovic
Affiliation:
National Infectious Diseases Service, Specialty Care Services, Veterans’ Affairs Central Office, Washington, DC Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio Cincinnati Veterans’ Affairs Medical Center, Cincinnati, Ohio
Gary A. Roselle
Affiliation:
National Infectious Diseases Service, Specialty Care Services, Veterans’ Affairs Central Office, Washington, DC Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio Cincinnati Veterans’ Affairs Medical Center, Cincinnati, Ohio
*
Author for correspondence: Brian P. McCauley, E-mail: brian.mccauley@va.gov

Abstract

Clostridioidesdifficile infection rates from 7 facilities that used nucleic acid amplification testing (NAAT) alone for 12 months then switched to NAAT plus toxin enzyme immunoassay (EIA) and reported the latter result for 12 months were compared to 70 facilities that used NAAT alone for all 24 months. There was no significant difference in rates between facility groups over the first 12 months (P = .21, linear regression), but we detected a decrease in rates for the facilities that changed to NAAT+EIA (P < .0001).

Type
Concise Communication
Copyright
© 2020 by The Society for Healthcare Epidemiology of America. All rights reserved.

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References

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