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Detection of Hepatitis C Virus Antibody and RNA in Hemostatic Gauze Used for Dentistry

Published online by Cambridge University Press:  02 January 2015

Hiromasa Hasegawa
Department of Pathology, Nihon University School of Medicine, Tokyo Department of Oral Pathology, Matsumoto Dental University School of Dentistry, Nagano
Tetsuo Yamada
Division of Oral and Maxillofacial Surgery, Aizawa Hospital, Nagano, Japan
Mariko Esumi*
Department of Pathology, Nihon University School of Medicine, Tokyo
Nihon University School of Medicine, Department of Pathology, 30-1, Ooyaguchikami-machi, Itabashi-ku, Tokyo 173-8610, Japan


We investigated whether the presence of hepatitis C virus (HCV) infection can be detected in hemostatic gauze used during oral treatments. We were able to detect both antibody to HCV and HCV RNA in samples from patients serologically proven to have HCV and also in gauze used for these patients that was left at room temperature even for as long as 24 hours. Thus, this method is useful for the screening of HCV infection in situations in which blood sampling is not feasible.

Concise Communications
Copyright © The Society for Healthcare Epidemiology of America 2003

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1.Brind, AM, Watson, JP, James, OF, Bassendine, MF. Hepatitis C virus infection in the elderly. QJM 1996;89:291296.CrossRefGoogle ScholarPubMed
2.Mizuno, M, Higuchi, T, Kanmatsuse, K, Esumi, M. Genetic and serological evidence for multiple instances of unrecognized transmission of hepatitis C virus in hemodialysis units. J Clin Microbiol 1998;36:29262931.CrossRefGoogle ScholarPubMed
3.Rooney, G, Gilson, RJ. Sexual transmission of hepatitis C virus infection. Sex Transm Infect 1998;74:399404.Google Scholar
4.Zanetti, AR, Tanzi, E, Romano, L, et al. A prospective study on mother-to-infant transmission of hepatitis C virus. Intervirology 1998;41:208212.Google Scholar
5.Piazza, M, Borgia, G, Picciotto, L, Nappa, S, Cicciarello, S, Orlando, R. Detection of hepatitis C virus-RNAby polymerase chain reaction in dental surgeries. J Med Virol 1995;45:4042.CrossRefGoogle ScholarPubMed
6.Porter, SR, Lodi, G. Hepatitis C virus (HCV): an occupational risk to dentists? Br Dent J 1996;180:473474.Google Scholar
7.Thomas, DL, Gruninger, SE, Siew, C, Joy, ED, Quinn, TC. Occupational risk of hepatitis C infections among general dentists and oral surgeons in North America. Am J Med 1996;100:4145.Google Scholar
8.Sugano, M, Hayashi, Y, Yoon, S, et al. Quantitation of hepatitis C viral RNA in liver and serum samples using competitive polymerase chain reaction. J Clin Pathol 1995;48:820825.Google Scholar
9.Chen, M, Yun, ZB, Sallberg, M, et al. Detection of hepatitis C virus RNA in the cell fraction of saliva before and after oral surgery. J Med Virol 1995;45:223226.CrossRefGoogle ScholarPubMed
10.Enomoto, A, Yoshino, S, Hasegawa, H, et al. Phylogenetic investigation for the risk of hepatitis C virus transmission to surgical and dental patients. J Viral Hepat 2001;8:148153.CrossRefGoogle ScholarPubMed