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Clearance Rate of Carbapenemase-Producing Enterobacteriaceae Carriage Among Hospitalized Patients

Published online by Cambridge University Press:  15 July 2015

Kyu-Ri Kim
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Jeong-Young Lee
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Hee-Youn Park
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Sun-Hee Kwak
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Young-Ju Lim
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Min-Jee Hong
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Sun-Kyung Kim
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
So-Yeon Park
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Hyeon-Jeong Kim
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Hye-Suk Choi
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea
Mi-Na Kim
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea Department of Laboratory Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
Hye-Ran Choi
Affiliation:
Department of Clinical Nursing, University of Ulsan College of Medicine, Seoul, Republic of Korea
Jae-Sim Jeong
Affiliation:
Department of Nursing, University of Ulsan, Seoul, Republic of Korea
Sang-Ho Choi*
Affiliation:
Office for Infection Control, Asan Medical Center, Seoul, Republic of Korea Department of Infectious Diseases, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
*
Address correspondence to Sang-Ho Choi, MD, PhD, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 138-736, Republic of Korea (sangho@amc.seoul.kr).

Abstract

During the past decade, carbapenemase-producing Enterobacteriaceae (CPE) has emerged and spread across the world.1 The major carbapenemase enzymes currently being reported are KPC, NDM-1, VIM, IMP, and OXA.2 Because carbapenemase can be effectively transmitted via mobile genetic elements, and current therapeutic options for CPE infections are extremely limited, CPE may be one of the most serious contemporary threats to public health. However, very little is known about the characteristics of CPE carriage during hospitalization. The aims of this study were to investigate the clearance rate of CPE carriage and determine the number of consecutive negative cultures required to confirm CPE clearance. We also examined CPE transmission among hospitalized patients.

Infect. Control Hosp. Epidemiol. 2015;36(11):1361–1362

Type
Research Briefs
Copyright
© 2015 by The Society for Healthcare Epidemiology of America. All rights reserved 

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Footnotes

K.-R.K. and J.-Y.L. contributed equally to this article

Presented in part: Society for Healthcare Epidemiology of America (SHEA) Spring 2015 Conference; Orlando, Florida; May 15, 2015 (Abstract 7102).

References

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