Skip to main content Accessibility help
×
Home
Hostname: page-component-59b7f5684b-7j4dq Total loading time: 0.639 Render date: 2022-10-02T18:30:15.632Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "useRatesEcommerce": false, "displayNetworkTab": true, "displayNetworkMapGraph": false, "useSa": true } hasContentIssue true

Benefit and cost of repeating a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) polymerase chain reaction (PCR) test after the second day of hospitalization in five hospitals during various community prevalences and vaccination rates

Published online by Cambridge University Press:  16 June 2022

Rene Bulnes
Affiliation:
Medicine Department, Rochester Regional Health, Rochester, New York
Mina Said
Affiliation:
Medicine Department, Rochester Regional Health, Rochester, New York
Melissa Bronstein
Affiliation:
Quality and Safety Department, Rochester Regional Health, Rochester, New York
Jennifer Gutowski
Affiliation:
Quality and Safety Department, Rochester Regional Health, Rochester, New York
Karan Alag
Affiliation:
Health Informatics, Rochester Regional Health, Rochester, New York
Jonathan Bress
Affiliation:
Medicine Department, Rochester Regional Health, Rochester, New York
Amber Dellefave
Affiliation:
Quality and Safety Department, Rochester Regional Health, Rochester, New York
Dawn Riedy
Affiliation:
Pathology Department, Rochester Regional Health, Rochester, New York
Jose Alcantara
Affiliation:
Health Informatics, Rochester Regional Health, Rochester, New York
Hiloni Bhavsar
Affiliation:
Quality and Safety Department, Rochester Regional Health, Rochester, New York
Bryan Gargano
Affiliation:
Executive Leadership, Rochester Regional Health, Rochester, New York
Emil Lesho*
Affiliation:
Infectious Diseases Department, Rochester Regional Health, Rochester, New York
*
Author for correspondence: Emil Lesho, E-mail: carolinelesho@yahoo.com

Abstract

At our hospital, universal severe acute respiratory coronavirus virus 2 (SARS-CoV-2) polymerase chain reaction (PCR) testing was performed upon admission and again after 2 inpatient days. As community-wide prevalence, admission, and vaccination rates varied, the number needed to benefit fluctuated between 16 and 769 and the cost per additional detection fluctuated between $800 and $29,400. These 2 metrics were negatively associated with new hospital admissions. No other community indicator was associated with the number needed to benefit and cost per additional detection.

Type
Concise Communication
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Elkrief, A, Desilets, A, Papneja, N, et al. High mortality among hospital-acquired COVID-19 infection in patients with cancer: a multicentre observational cohort study. Eur J Cancer 2020;139:181187.CrossRefGoogle ScholarPubMed
Khonyongwa, K, Taori, SK, Soares, A, et al. Incidence and outcomes of healthcare-associated COVID-19 infections: significance of delayed diagnosis and correlation with staff absence. J Hosp Infect 2020;106:663672.CrossRefGoogle ScholarPubMed
Lessells, R, Moosa, Y, de Oliveira, T. Report into a nosocomial outbreak of coronavirus disease 2019 (COVID-19) at Netcare St. Augustine’s Hospital. University of Kwazulu-Natal website. https://www.groundup.org.za/media/uploads/documents/staugustineshospitaloutbreakinvestigation_finalreport_15may2020.pdf. Published May 2020. Accessed January 26, 2021.Google Scholar
Pfoh, ER, Hariri, EH, Misra-Hebert, AD, Deshpande, A, Jehi, L, Rothberg, MB. Late diagnosis of COVID-19 in patients admitted to the hospital. J Gen Intern Med 2020;35:28292831.CrossRefGoogle ScholarPubMed
Kucirka, LM, Lauer, SA, Laeyendecker, O, Boon, D, Lessler, J. Variation in false-negative rate of reverse transcriptase polymerase chain reaction-based SARS-CoV-2 tests by time since exposure. Ann Intern Med 2020;173:262267.CrossRefGoogle ScholarPubMed
Lesho, E, Walsh, E, Gutowski, J, et al. A cluster-control approach to a SARS-CoV-2 outbreak on a stroke ward with infection control considerations for dementia and vascular units. Infect Control Hosp Epidemiol 2021;42:13331339.CrossRefGoogle ScholarPubMed
Rhee, C, Baker, M, Vaidya, V, et al. Incidence of nosocomial COVID-19 in patients hospitalized at a large US academic medical center. JAMA Netw Open 2020;3:e2020498.CrossRefGoogle Scholar
Lesho, E, Reno, L, Newhart, D, et al. Temporal, spatial, and epidemiologic relationships of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gene cycle thresholds: a pragmatic ambidirectional observation. Clin Infect Dis 2020;ciaa1248.CrossRefGoogle Scholar
In COVID-19 testing, what does yield mean? University of North Carolina website. https://gillingscovid19.unc.edu/coronavirus-questions/covid-19-testing-yield. Accessed December 8, 2021.Google Scholar
Honorio, MR, Benzon, HT, Molloy, RE. Membrane stablizers, in essentials of pain medicine and regional anesthesia, second edition. Science Direct website. https://www.sciencedirect.com/topics/medicine-and-dentistry/numbers-needed-to-treat. Published 2005. Accessed December 8, 2021.Google Scholar
Supplementary material: Image

Bulnes et al. supplementary material

Bulnes et al. supplementary material

Download Bulnes et al. supplementary material(Image)
Image 300 KB

Save article to Kindle

To save this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Benefit and cost of repeating a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) polymerase chain reaction (PCR) test after the second day of hospitalization in five hospitals during various community prevalences and vaccination rates
Available formats
×

Save article to Dropbox

To save this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you used this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about saving content to Dropbox.

Benefit and cost of repeating a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) polymerase chain reaction (PCR) test after the second day of hospitalization in five hospitals during various community prevalences and vaccination rates
Available formats
×

Save article to Google Drive

To save this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you used this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about saving content to Google Drive.

Benefit and cost of repeating a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) polymerase chain reaction (PCR) test after the second day of hospitalization in five hospitals during various community prevalences and vaccination rates
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *