We present results of our ongoing observing program on search and studies of massive stars (O and WR type) in binary systems in our neighbor galaxies, the Magellanic Clouds. Radial velocity orbits are presented for two new binaries, one in the Small Magellanic Cloud and another in the Large Magellanic Cloud, and improved orbits for previously known systems. We compare orbital parameters of selected binaries containing O and WR type components. We also discuss the present status of knowledge for massive binary stars in the Magellanic Clouds and the problems encountered in their orbital studies such as stellar winds the ubiquitous tendency to be born in multiple systems.