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A sex-linked coat-colour mutation in the mouse non-transmissible through the female

Published online by Cambridge University Press:  14 April 2009

Jean-Louis Guenet
Jean-Louis Guenet
Affiliation:
Unité de Génétique cellulaire du Collège de France et de l'Institut Pasteur, 25 rue du Dr. Roux, 75015 Paris, France
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Summary

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A sex-linked mutation with a phenotype similar to that of an allele of the Mottled series has been discovered in a mosaic male. This mutation can be normally transmitted through the sperm of the original male but not through the oocytes. Several interpretations of this abnormal transmission are discussed.

Type
Research Article
Information
Genetics Research , Volume 33 , Issue 2 , April 1979 , pp. 163 - 167
Copyright
Copyright © Cambridge University Press 1979

References

REFERENCES

Auerbach, C., Falconer, D. S. & Isaacson, J. H. (1962). Test for sex-linked lethals in irradiated mice. Genetical Research 3, 444–447.CrossRefGoogle Scholar
Cattanach, B. M. & Williams, C. E. (1972). Evidence of non-random X chromosome activity in the mouse. Genetical Research 19, 229–240.CrossRefGoogle ScholarPubMed
Dickie, M. M. (1954). The tortoise shell house mouse. Journal of Heredity 45, 158 and 190.CrossRefGoogle Scholar
Edwards, R. G. & Fowler, R. E. (1959). Fetal mortality in adult mice after superovulation with gonadotrophins. Journal of Experimental Zoology 141, 299–322.CrossRefGoogle ScholarPubMed
Fraser, A. S., Sobey, S. & Spicer, C. C. (1953). Mottled a sex modified lethal in the house mouse. Journal of Genetics. 51, 217–221.CrossRefGoogle Scholar
Grahn, D., Leslie, W. P., Verley, F. A. & Lea, R. A. (1972). Determination of the radiation-induced mutation rate for sex-linked lethals and detrimentals in the mouse. Mutation Research 15, 331–347.CrossRefGoogle ScholarPubMed
Hunt, D. M. (1976). A study of copper treatment and tissue copper levels in the murine congenital copper deficiency mottled. Life Sciences 19, 1913–1920.CrossRefGoogle ScholarPubMed
Johnson, D. R. (1974). Hairpin tail: a case of post reduction gene action in the mouse egg? Genetics, 76, 795–805.CrossRefGoogle Scholar
Johnson, D. R. (1975). Further observations on the hairpin-tail (T Hp) mutation in the mouse. Genetical Research 24, 207–213.CrossRefGoogle Scholar
Lyon, M. F. (1960). A further mutation of the mottled type in the house mouse. Journal of Heredity 51, 116–121.CrossRefGoogle Scholar
Lyon, M. F. (1961). Gene action in the X chromosome of the mouse (Mus musculus L). Nature 190, 372–373.CrossRefGoogle ScholarPubMed
Lyon, M. F. (1972). X-chromosome inactivation and developmental patterns in mammals. Biological Reviews 47, 1–35.CrossRefGoogle ScholarPubMed
Phillips, R. J. S. (1961). ‘Dappled’, a new allele at the mottled locus in the house mouse. Genetical Research 2, 290–295.CrossRefGoogle Scholar
Phillips, R. J. S. (1963). Striated, a new sex linked gene in the house mouse. Genet. Res. 4, 151–153.CrossRefGoogle Scholar
Schböder, J. H. (1971). A search for radiation induced recessive sex-linked lethal and detrimental mutation in. immature germ cells of the house mouse. (Mus musculus). Genetics 68, 35–57.CrossRefGoogle Scholar
Searle, A. G. (1968). Comparative Genetics of Coat Colour in Mammals. London and New York: Academic Press Ltd.Google Scholar
Searle, A. G. (1973). Mutation induction in mice. Advances in Radiation Biology 4, 131–207.CrossRefGoogle Scholar
Tagaki, N. & Sasaki, M. (1972). Preferential inactivation of the paternally derived X chromosome in the extra embryonic membranes of the mouse. Nature 256, 640–642.CrossRefGoogle Scholar
West, J. D., Frels, W. I., Chapman, V. M. & Papaioannou, V. E. (1977). Preferential expression of the maternally derived X chromosome in the mouse yolk sac. Cell 12, 873–882.CrossRefGoogle ScholarPubMed