Hostname: page-component-848d4c4894-jbqgn Total loading time: 0 Render date: 2024-06-30T08:48:40.486Z Has data issue: false hasContentIssue false
  • English
  • Français

Major urinary protein and immunoglobulin allotypes of recombinant inbred mouse strains

Published online by Cambridge University Press:  14 April 2009

M. Potter ,
J. S. Finlayson ,
D. W. Bailey ,
E. B. Mushinski ,
B. L. Reamer  and
J. L. Walters
M. Potter
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
J. S. Finlayson
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
D. W. Bailey
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
E. B. Mushinski
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
B. L. Reamer
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
J. L. Walters
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Serum and urine samples from seven recombinant inbred mouse strains, derived from a cross between BALB/c and C57BL/6, were examined to determine the immunoglobulin heavy chain (IgCH) and the major urinary protein (MUP) allotypes. CXBG and CXBJ exhibited the same IgCH alleles as did BALB/c; the others resembled C57BL/6, thus providing no evidence of crossover types. Comparison of the Mup and brown coat colour (b) alleles (both on linkage group VIII) revealed that three of the strains resemble BALB/c and two resemble C57BL/6, whereas the CXBE and CXBI strains are crossover types.

Type
Short Papers
Information
Genetics Research , Volume 22 , Issue 3 , December 1973 , pp. 325 - 328
Copyright
Copyright © Cambridge University Press 1973

References

REFERENCES

Bailey, D. W. (1971). Recombinant-inbred strains. An aid to finding identity, linkage, and function of histocompatibility and other genes. Transplantation 11, 325–327.CrossRefGoogle ScholarPubMed
Finlayson, J. S., Hudson, D. M. & Armstrong, B. L. (1969). Location of the Mup-a locus on mouse linkage group VIII. Genetical Research 14, 329–331.CrossRefGoogle Scholar
Finlayson, J. S., Potter, M. & Runner, C. C. (1963). Electrophoretic variation and sex dimorphism of the major urinary protein complex in inbred mice: a new genetic marker. Journal of the National Cancer Institute 31, 91–107.Google ScholarPubMed
Herzenberg, L. A., McDevitt, H. O. & Herzenberg, L. A. (1968). Genetics of antibodies. Annual Review of Genetics 2, 209–244.CrossRefGoogle Scholar
Hoffman, H. A. (1970). Starch-gel electrophoresis of murine major urinary protein. Proceedings of the Society for Experimental Biology and Medicine 135, 81–83.CrossRefGoogle Scholar
Hudson, D. M., Finlayson, J. S. & Potter, M. (1967). Linkage of one component of the major urinary protein complex of mice to the brown coat color locus. Genetical Research 10, 195–198.CrossRefGoogle Scholar
Minna, J. D., Iverson, G. M. & Herzenberg, L. A. (1967). Identification of a gene locus for γG1 immunoglobulin H chains and its linkage to the H chain chromosome region in the mouse. Proceedings of the National Academy of Sciences, U.S.A. 58, 188–194.CrossRefGoogle Scholar
Potter, M. (1972). Immunoglobulin-producing tumors and myeloma proteins of mice. Physiological Reviews 52, 631–719.CrossRefGoogle ScholarPubMed
Potter, M. & Lieberman, R. (1967). Genetic studies of immunoglobulins in mice. Cold Spring Harbor Symposia on Quantitative Biology 32, 187–202.CrossRefGoogle Scholar
Reuter, A. M., Kennes, F., Leonard, A. & Sassen, A. (1968). Variations of the prealbumin in serum and urine of mice, according to strain and sex. Comparative Biochemistry and Physiology 25, 921–928.CrossRefGoogle ScholarPubMed