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Major urinary protein and immunoglobulin allotypes of recombinant inbred mouse strains

Published online by Cambridge University Press:  14 April 2009

M. Potter ,
J. S. Finlayson ,
D. W. Bailey ,
E. B. Mushinski ,
B. L. Reamer  and
J. L. Walters
M. Potter
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
J. S. Finlayson
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
D. W. Bailey
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
E. B. Mushinski
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
B. L. Reamer
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.
J. L. Walters
Affiliation:
Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland, 20014; Bureau of Biologics, Food and Drug Administration, Bethesda, Maryland, 20014; and The Jackson Laboratory, Bar Harbor, Maine, 04609, U.S.A.

Summary

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Serum and urine samples from seven recombinant inbred mouse strains, derived from a cross between BALB/c and C57BL/6, were examined to determine the immunoglobulin heavy chain (IgCH) and the major urinary protein (MUP) allotypes. CXBG and CXBJ exhibited the same IgCH alleles as did BALB/c; the others resembled C57BL/6, thus providing no evidence of crossover types. Comparison of the Mup and brown coat colour (b) alleles (both on linkage group VIII) revealed that three of the strains resemble BALB/c and two resemble C57BL/6, whereas the CXBE and CXBI strains are crossover types.

Type
Short Papers
Information
Genetics Research , Volume 22 , Issue 3 , December 1973 , pp. 325 - 328
Copyright
Copyright © Cambridge University Press 1973

References

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