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The genetics of Sleek: a possible regulatory mutation of the tabby-crinkled-downless syndrome

  • Mark Crocker (a1) and Bruce M. Cattanach (a1)

Summary

A new mutation, Sleek, similar in appearance to mutations at the Ta, cr and dl loci, has been investigated. It is inherited as an autosomal dominant and maps very close to dl on chromosome 13. Allelism with dl seems probable since Sleek interacts with dl but not with cr. The unusual occurrence of dominant and recessive alleles at the same locus which produce a similar mutant phenotype suggests that the locus might either code for a multimeric protein or a regulatory product.

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References

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Beckwith, J. & Rossow, P. (1974). Analysis of genetic regulatory mechanisms. Annual Review of Genetics 9, 113.
Britten, R. J. & Davidson, E. H. (1969). Gene regulation for higher cells: a theory. Science 165, 349357.
Cattanach, B. M. (1975). Mouse News Letter 53, 29.
Dun, R. B. & Fraser, A. S. (1959). Selection for an invariant character, vibrissa number in the house mouse. Australian Journal of Biological Science 12, 506523.
Falconer, D. S. (1953). Total sex linkage in the house mouse. Zeitschrift für induktive Abstammungs- und Vererbungslehre 85, 210219.
Falconer, D. S., Fraser, A. S. & King, J. W. B. (1951). The genetics and development of ‘crinkled’ a new mutant in the house mouse. Journal of Genetics 50, 324344.
Hagen, D. C., Lipton, P. J. & Magasanik, B. (1974). Isolation of a raws-dominant histidasenegative mutant of Salmonella typhimurium. Journal of Bacteriology 120, 906916.
Grüneburg, H. (1971). The tabby syndrome in the mouse. Proceedings of the Royal Society of London B 179, 139156.
Kacser, H. & Burns, J. A. (1973). The control of flux. In Rate control of Biological Processes. Symposium of the Society for Experimental Biology, no. XXVII, pp. 65–104.
Kindred, B. (1967). Some observations on the skin and hair of Tabby mice. Journal of Heredity 58, 197199.
Phillips, R. J. S. (1960.) Private communication. Mouse News Letter 23, 29.
Sofaer, J. A. (1969 a). Aspects of the tabby–crinkled–downless syndrome. I. The development of tabby teeth. Journal of Embryology and Experimental Morphology 22, 181205.
Sofaer, J. A. (1969 b). Aspects of the tabby–crinkled–downless syndrome. II. Observations on the reaction to changes of genetic background. Journal of Embryology and Experimental Morphology 22, 207227.
Sofaer, J. A. (1977). The teeth of the ‘Sleek’ mouse. Archives of oral Biology 22, 299301.

The genetics of Sleek: a possible regulatory mutation of the tabby-crinkled-downless syndrome

  • Mark Crocker (a1) and Bruce M. Cattanach (a1)

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