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Cytoplasmic isocitrate dehydrogenase variation within the C3H inbred strain

Published online by Cambridge University Press:  14 April 2009

Anne McLaren  and
Andrew Taita
Anne McLaren
Affiliation:
Institute of Animal Genetics, Edinburgh 9
Andrew Taita
Affiliation:
Institute of Animal Genetics, Edinburgh 9

Extract

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Two allelic forms of the supernatant NADP isocitrate dehydrogenase (IDH) are found in inbred strains of mice (Henderson, 1965). The five C3H substrains tested, namely C3H/HeJ, C3H/Re-sl, C3H/N-wJ+, C3H/J-WX+ and C3HeB/FeJ, all proved to be of the Id-la/Id-la genetic constitution. (For the nomenclature of inbred strains and substrains of mice see Staats, Committee on Standardized Nomenclature for Inbred Strains of Mice, Cancer Res. 24 (1964), 147–168.) All these substrains were obtained from E. S. Russell at the Jackson Memorial Laboratory, Bar Harbor, Maine, and were presumably all derived from C3H/He mice.

Type
Short Papers
Information
Genetics Research , Volume 14 , Issue 1 , August 1969 , pp. 93 - 94
Copyright
Copyright © Cambridge University Press 1969

References

REFERENCES

Festing, M. F. W. (1969). Inbred mice in research. Nature, Lond. 221, 716.CrossRefGoogle ScholarPubMed
Fine, T. H. & Costello, L. A. (1963). The use of starch electrophoresis in dehydrogenase studies. Methods Enzymol. 6, 958–972.CrossRefGoogle Scholar
Green, E. L. (1953). A skeletal difference between sublines of the C3H strain of mice. Science, N.Y. 117, 81–82.CrossRefGoogle ScholarPubMed
Henderson, N. S. (1965). Isozymes of isocitrate dehydrogenase: subunit structure and intracellular location. J. exp. Zool. 158, 263–274.CrossRefGoogle ScholarPubMed
McLaren, A. & Michie, D. (1954). Factors affecting vertebral variation in mice. I. Variation within an inbred strain. J. Embryol. exp. Morph. 2, 149–160.Google Scholar