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Chromosomal localisation of the mouse and human peripherin genes

Published online by Cambridge University Press:  14 April 2009

Anne Moncla
Affiliation:
Centre de Génétique médicale, Institut National de la Santé et de la Recherche Médicale U242, Hôpital d'enfants de la Timone, F-13385 Marseille Cedex, France
Françoise Landon
Affiliation:
Laboratoire de Biochimie Cellulaire, Collège de France, 11 place Marcellin Berthelot, F-75231 Paris Cedex 5
Marie-Genevieve Mattei
Affiliation:
Centre de Génétique médicale, Institut National de la Santé et de la Recherche Médicale U242, Hôpital d'enfants de la Timone, F-13385 Marseille Cedex, France
Marie-Madeleine Portier*
Affiliation:
Laboratoire de Biochimie Cellulaire, Collège de France, 11 place Marcellin Berthelot, F-75231 Paris Cedex 5
*
* Corresponding author.
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Using a mouse cDNA probe encoding for the major part of peripherin, a type III intermediate filament protein, we have assigned, by in situ hybridization, the mouse and human peripherin genes, Prph, to the E–F region of chromosome 15 and to the q12–q13 region of chromosome 12, respectively. These regions are known as homologous chromosomal segments containing other intermediate filament genes (keratins) and also other genes which could be co-ordinately regulated.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1992

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