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Aeruginocin tolerant mutants of Pseudomonas aeruginosa

Published online by Cambridge University Press:  14 April 2009

B. W. Holloway ,
Heidi Rossiter ,
Diana Burgess  and
Judy Dodge
B. W. Holloway
Affiliation:
Department of Genetics, Monash University, Clayton, Victoria 3168, Australia
Heidi Rossiter
Affiliation:
Department of Genetics, Monash University, Clayton, Victoria 3168, Australia
Diana Burgess
Affiliation:
Department of Genetics, Monash University, Clayton, Victoria 3168, Australia
Judy Dodge
Affiliation:
Department of Genetics, Monash University, Clayton, Victoria 3168, Australia

Summary

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Mutants of Pseudomonas aeruginosa tolerant to the action of trypsinsensitive aeruginocins can be readily isolated. They are found to be heterogeneous for a range of phenotypic characteristics (including the pattern of membrane protein components in polyacrylamide gel electrophoresis), response to bacteriophages (including both plaque formation and the ability to be lysogenized), sensitivity to various toxic agents, colonial morphology, and cellular morphology. The nature of these changes strongly supports the view that the mutants examined have undergone alteration in membrane structure. A limited genetic analysis indicates that at least two chromosomal regions are involved.

Type
Research Article
Information
Genetics Research , Volume 22 , Issue 3 , December 1973 , pp. 239 - 253
Copyright
Copyright © Cambridge University Press 1973

References

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