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The role of uterine prostaglandins in the initiation and maintenace of labour

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  01 May 1999

Jocelynn L Cook  and
David M Olson
Jocelynn L Cook
Affiliation:
The Perinatal Research Centre, Departments of Obstetrics and Gynaecology, Pediatrics and Physiology, The University of Alberta, Edmonton, Alberta, Canada
David M Olson
Affiliation:
The Perinatal Research Centre, Departments of Obstetrics and Gynaecology, Pediatrics and Physiology, The University of Alberta, Edmonton, Alberta, Canada
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Abstract

This review will focus largely on the prostaglandins (PGs) in relation to term and preterm birth and highlight some of the newer concepts in this field including the pathways of maternal and fetal PG synthesis, metabolism and receptors. Data from studies in women or from experiments utilizing human gestational tissues will be combined with knowledge gained from animal experiments. An attempt will be made to provide a straightforward, updated view of the role of PGs in these processes. Potential therapeutic strategies for delaying preterm birth and prolonging pregnancy will also be discussed.

Type
Research Article
Information
Fetal and Maternal Medicine Review , Volume 11 , Issue 2 , May 1999 , pp. 69 - 78
Copyright
© 1999 Cambridge University Press

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