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GENETICS OF HYPOPLASTIC LEFT HEART SYNDROME

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  01 May 2007

HELEN COX  and
DAVID I WILSON
HELEN COX*
Affiliation:
Clinical Genetics Unit, Birmingham Women's Hospital, Birmingham
DAVID I WILSON
Affiliation:
Human Genetics, The Duthie Building (MP808) Southampton General Hospital, Tremona Road, Southampton SO16 6YD
*
Helen Cox, Clinical Genetics Unit, Birmingham Women's Hospital, Metchley Park Road, Edgbaston, Birmingham B15 2TG.
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Extract

The aetiology of hypoplastic left heart syndrome (HLH) is complex and involves both genetic and environmental factors. Hypoplastic left heart syndrome accounts for 1.4–3.8% of all congenital heart defects but up to 25% of neonatal deaths. As well as having a high mortality, HLH is a very significant cause of morbidity and therefore justifies aetiological investigation.

Type
Research Article
Information
Fetal and Maternal Medicine Review , Volume 18 , Issue 2 , May 2007 , pp. 103 - 119
Copyright
Copyright © Cambridge University Press 2007

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