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Volumetric change of the lateral ventricles in the human brain following glucose loading

  • B. K. Puri (a1), H. J. Lewis (a1), N. Saeed (a1) and N. J. Davey (a2)

Abstract

Lateral ventricular volumes were monitored and quantified using accurately registered magnetic resonance images (MRIs) in six healthy individuals 30 min before and up to 4 h after ingestion of a glucose drink. The volume of the lateral ventricles increased by an average (± S.E.M.) of 2Σ4 ± 0Σ4 % as blood glucose levels rose from 4Σ8 ± 0Σ2 mmol l-1 to 8Σ4 ± 0Σ4 mmol l-1. This was followed by a peak decrease of 5Σ99 ± 3Σ3 % below initial fasting volumes as blood glucose levels fell to 5Σ0 ± 0Σ3 mmol l-1. We suggest that the secondary volume decrease demonstrates a homeostatic process of brain volume regulation for which the mechanism remains uncertain.

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Volumetric change of the lateral ventricles in the human brain following glucose loading

  • B. K. Puri (a1), H. J. Lewis (a1), N. Saeed (a1) and N. J. Davey (a2)

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