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Validation of the modified mini- mental state examination (3ms) in a German population

Published online by Cambridge University Press:  16 April 2020

P. Alexopoulos ,
K. Nadler ,
B. Cramer ,
S. Herpertz  and
A. Kurz
P. Alexopoulos
Affiliation:
Department of Psychiatry and Psychotherapy, Universitaet Rostock, Rostock, Germany Department of Psychiatry and Psychotherapy, Universitaet Erlangen- Nuernberg, Erlangen, Germany
K. Nadler
Affiliation:
Department of Psychiatry and Psychotherapy, Universitaet Rostock, Rostock, Germany
B. Cramer
Affiliation:
Department of Psychiatry and Psychotherapy, Technische Universitaet Muenchen, Muenchen, Germany
S. Herpertz
Affiliation:
Department of Psychiatry and Psychotherapy, Universitaet Rostock, Rostock, Germany
A. Kurz
Affiliation:
Department of Psychiatry and Psychotherapy, Technische Universitaet Muenchen, Muenchen, Germany

Abstract

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Background:

The Modified Mini- Mental State Examination (3MS) is a brief cognitive testbattery designed to detect cognitive impairment.

Objective:

To adapt the 3MS in German and to assess the effectiveness of the 3MS in identifying Alzheimer's disease (AD) in comparison with the conventional Mini- Mental State Examination (MMSE) in a German population.

Subjects:

A clinical group composed of 31 patients with early AD and 5 patients with moderate dementia of AD etiology was compared with 46 cognitively normal participants matched for gender and age. The 3MS scores were adjusted for educational attainment.

Method:

The 3MS and MMSE were validated against an expert diagnosis based on a comprehensive diagnostic work- up. Statistical analysis was performed using the Receiver Operating Characteristics (ROC)

Results:

ROC curves demonstrated the superiority of the 3MS over the MMSE in identifying AD. The optimal cut- off score for the 3MS for detecting dementia was 88, which had a sensitivity of 98% and a specificity of 94%.

Conclusion:

The German version of the 3MS is a short and practical but accurate test battery for the identification of AD.

Type
Poster Session 2: Organic Mental Disorders and Memory and Cognitive Dysfunctions
Information
European Psychiatry , Volume 22 , Issue S1: 15th AEP Congress - Abstract book - 15th AEP Congress , March 2007 , pp. S295
Copyright
Copyright © European Psychiatric Association 2007
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