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Sustained and selective attention deficits as vulnerability markers to psychosis

Published online by Cambridge University Press:  16 April 2020

B. Mulet ,
J. Valero ,
A. Gutiérrez-Zotes ,
C. Montserrat ,
M.J. Cortés ,
M. Jariod ,
L. Martorell ,
E. Vilella  and
A. Labad
B. Mulet*
Affiliation:
Departament de Formació i Investigació, Hospital Psiquià tric Universitari Institut Pere Mata, Ctra. de l'Institut, s/n, 43206 Reus, Tarragona, Spain
J. Valero
Affiliation:
Departament de Formació i Investigació, Hospital Psiquià tric Universitari Institut Pere Mata, Ctra. de l'Institut, s/n, 43206 Reus, Tarragona, Spain Unitat de Psiquiatria i Psicologia Mèdica, Departament de Medicina i Cirurgia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Sant Llorenç, 21, 43201Reus, Spain
A. Gutiérrez-Zotes
Affiliation:
Departament de Formació i Investigació, Hospital Psiquià tric Universitari Institut Pere Mata, Ctra. de l'Institut, s/n, 43206 Reus, Tarragona, Spain Unitat de Psiquiatria i Psicologia Mèdica, Departament de Medicina i Cirurgia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Sant Llorenç, 21, 43201Reus, Spain
C. Montserrat
Affiliation:
Departament de Formació i Investigació, Hospital Psiquià tric Universitari Institut Pere Mata, Ctra. de l'Institut, s/n, 43206 Reus, Tarragona, Spain
M.J. Cortés
Affiliation:
Unitat de Psiquiatria i Psicologia Mèdica, Departament de Medicina i Cirurgia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Sant Llorenç, 21, 43201Reus, Spain
M. Jariod
Affiliation:
Unitat de Psiquiatria i Psicologia Mèdica, Departament de Medicina i Cirurgia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Sant Llorenç, 21, 43201Reus, Spain
L. Martorell
Affiliation:
Departament de Formació i Investigació, Hospital Psiquià tric Universitari Institut Pere Mata, Ctra. de l'Institut, s/n, 43206 Reus, Tarragona, Spain
E. Vilella
Affiliation:
Departament de Formació i Investigació, Hospital Psiquià tric Universitari Institut Pere Mata, Ctra. de l'Institut, s/n, 43206 Reus, Tarragona, Spain Unitat de Psiquiatria i Psicologia Mèdica, Departament de Medicina i Cirurgia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Sant Llorenç, 21, 43201Reus, Spain
A. Labad
Affiliation:
Departament de Formació i Investigació, Hospital Psiquià tric Universitari Institut Pere Mata, Ctra. de l'Institut, s/n, 43206 Reus, Tarragona, Spain Unitat de Psiquiatria i Psicologia Mèdica, Departament de Medicina i Cirurgia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Sant Llorenç, 21, 43201Reus, Spain
*
*Corresponding author. Tel.: +34 977 33 85 65x208; fax: +34 977 31 0021. E-mail address:muletb@peremata.com (B. Mulet).
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Abstract

The first descriptions of schizophrenia emphasized attention problems patients with schizophrenia have but recent results evidence that other psychotic disorders share them.

We compared the performance in sustained and selective attention between psychotic patients (P), their healthy first degree relatives (R) and healthy volunteers (C) to prove whether these alterations could be an endophenotype of vulnerability to psychosis. We also compared the performance of schizophrenic patients (SZP) and that of patients with other functional psychoses (OP) in order to prove whether these alterations are specific of any psychotic disorder.

Seventy-six P, 70 R and 39 C were included in the study. A selective attention index, comprising TMT A and B and Stroop Test, and a sustained attention index comprising the Continuous Performance Test were calculated. We conducted an univariant general linear model to compare three group performances in these indexes, with age, sex and years of education as a covariables.

We found significant differences between the indexes when we compared P, R and C. No differences in performance were found between SZP and OP. Our data showed that sustained and selective attention alterations could be a vulnerability factor to psychotic disorders in general, but they were not specific of schizophrenia.

Keywords

AttentionCognitionEndophenotypeNeuropsychologyPsychosisVigilance
Type
Schizophrenia and Psychotic Disorder
Information
European Psychiatry , Volume 22 , Issue 3 , April 2007 , pp. 171 - 176
Copyright
Copyright © Elsevier Masson SAS 2007

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