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Performance of the Mood Disorder Questionnaire (MDQ) according to bipolar subtype and symptom severity

Published online by Cambridge University Press:  16 April 2020

Nicola Gervasoni ,
Béatrice Weber Rouget ,
Mélissa Miguez ,
Vesselin Dubuis ,
Vera Bizzini ,
Marianne Gex-Fabry ,
Guido Bondolfi  and
Jean-Michel Aubry
Nicola Gervasoni
Affiliation:
Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland
Béatrice Weber Rouget
Affiliation:
Bipolar Program, Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland
Mélissa Miguez
Affiliation:
Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland
Vesselin Dubuis
Affiliation:
Bipolar Program, Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland
Vera Bizzini
Affiliation:
Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland
Marianne Gex-Fabry
Affiliation:
Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland
Guido Bondolfi
Affiliation:
Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland
Jean-Michel Aubry*
Affiliation:
Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland Bipolar Program, Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Switzerland
*
*Corresponding author. Bipolar Program, Service of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, 6-8, rue du 31-Décembre, 1207 Genève, Switzerland. Tel.: +41 22 718 45 38; fax: +41 22 718 45 99. E-mail address: jean-michel.aubry@hcuge.ch (J.-M. Aubry).
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Abstract

Objective

To evaluate the performance of the French version of the Mood Disorder Questionnaire (MDQ) in patients attending a general psychiatric outpatient service as well as whether MDQ scores are independent of patient mood state at time of completion.

Method

183 patients completed the MDQ and were assessed with the MADRS and YMRS scales, before being interviewed with the SCID (time 1). MDQ, MADRS and YMRS assessment was repeated four to six weeks later (time 2).

Results

According to the SCID, 44 patients were suffering from bipolar spectrum disorder and 102 from unipolar disorder (37 patients dropped out). The MDQ provided high specificity (83.3%). Sensitivity was 63.6%, with better identification of bipolar I (85.0%) than bipolar II patients (45.8%). In the whole sample, test-retest reliability was satisfactory (kappa = 0.64). Modest correlations were observed between the number of endorsed MDQ items and YMRS scores at time 1 (Spearman r = 0.19; p = 0.021) and time 2 (r = 0.26; p = 0.002).

Conclusions

Despite some fluctuations over time and a discrete influence of symptom severity, the screening algorithm can be used reliably, whether in the acute or remission phase of a depressive episode.

Keywords

Bipolar disorderDiagnosisQuestionnairesDepressionHypomania
Type
Original article
Information
European Psychiatry , Volume 24 , Issue 5 , June 2009 , pp. 341 - 344
Copyright
Copyright © Elsevier Masson SAS 2009

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