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Cognitive functioning in schizophrenic patients and their siblings

Published online by Cambridge University Press:  16 April 2020

A.M. Zaharie
Affiliation:
Psychiatric Hospital Nr. 2, Cluj-Napoca, Romania
I.V. Miclutia
Affiliation:
University of Medicine and Pharmacy “Iuliu Hatieganu”, Cluj-Napoca, Romania
C.A. Popescu
Affiliation:
Psychiatric Hospital Nr. 2, Cluj-Napoca, Romania
M. Stanculete
Affiliation:
University of Medicine and Pharmacy “Iuliu Hatieganu”, Cluj-Napoca, Romania

Abstract

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Background:

Recent years have seen a particular attention towards the research of particularities of cognitive processes in schizophrenia.

Objectives:

This study aims to investigate neuropsychological impairment in schizophrenia patients and their siblings.

Method:

Cognitive functioning in 30 schizophrenia patients, 30 unaffected siblings and 30 unrelated healthy controls was assessed using verbal fluency tests (letters and categories) and several computerized memory and executive function tests.

Results:

The patients performed significantly poorer than controls on all cognitive tests. Unaffected siblings demonstrated better performance than patients on some measures of spatial memory and executive function, but the performance was worse then controls. Patients and siblings demonstrated impaired verbal fluency performance.

Conclusions:

Patients with schizophrenia and theirs unaffected siblings shared a deficit in verbal fluency.

Type
Poster Session 1: Schizophrenia and Other Psychosis
Copyright
Copyright © European Psychiatric Association 2007
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