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The influence of temperament on symptoms and functional outcome in people with psychosis in the Northern Finland 1966 Birth Cohort

Published online by Cambridge University Press:  16 April 2020

L. Poustka
Affiliation:
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, J5, 68159Mannheim, Germany
G.K. Murray
Affiliation:
Department of Psychiatry, University of Cambridge, UK Behavioural and Clinical Neuroscience Institute, University of Cambridge, UK
E. Jääskeläinen
Affiliation:
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland
J. Veijola
Affiliation:
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland Academy of Finland, Helsinki, Finland
P. Jones
Affiliation:
Department of Psychiatry, University of Cambridge, UK
M. Isohanni
Affiliation:
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland Institute of Health Sciences, University of Oulu, and Department of Child and Adolescent Health, National Public Health Institute, and Unit of General Practice, Oulu University Hospital, Oulu, Finland
J. Miettunen
Affiliation:
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland
Corresponding
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Abstract

Objective

To describe symptom expression and functional outcome in psychotic disorders in relation with temperament traits assessed with the Temperament and Character Inventory (TCI) in a population-based sample.

Method

As part of the 31-year follow-up survey of the Northern Finland 1966 Birth Cohort, TCI temperament items were filled in by 4349 members of the cohort. In individuals with psychotic disorders, also positive and negative symptoms and outcome variables were assessed in a 35-year follow-up. Information of TCI and outcomes were available for altogether 41 individuals with psychosis.

Result

Reward dependence (RD) (rho = −0.45) and Persistence (P) (rho = −0.52) were significantly correlated with Positive and Negative Syndrome Scale (PANSS) negative symptoms. Higher P scores predicted higher social and occupational functioning (as measured by Social and Occupational Functioning Assessment Scale [SOFAS]), and higher Harm avoidance (HA) predicted a higher likelihood of being on a disability pension.

Conclusion

Results indicate that understanding of personality dimensions support better understanding of outcome and symptom expressions in psychotic disorders.

Type
Original articles
Copyright
Copyright © Elsevier Masson SAS 2010

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References

Ando, J., Ono, Y., Yoshimura, K.The genetic structure of Cloningers seven factor model of temperament and Character. J Pers 2002;70:583609.Google Scholar
Bleuler, E., Zinkin, J.Dementia Praecox or the Group of Schizophrenias. New York; International University Press; 1950.Google Scholar
Boeker, H., Kleiser, M., Lehmann, D., Jaenke, L., Bogerts, B., Northoff, G.Executive dysfunction, self and ego pathology in schizophrenia: an exploratory study of neuropsychology and personality. Compr Psychiatry 2006 47(1)719.CrossRefGoogle Scholar
Buchanan, R.W., Javitt, D.C., Marder, S.R., Schooler, N.R., Gold, J.M., McMahon, R.P.et al. The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments. Am J Psychiatry 2007 164(10)15931602.CrossRefGoogle ScholarPubMed
Cloninger, C.R.Temperament and personality. Curr Opin Neurobiol 1994;4:266273.CrossRefGoogle Scholar
Cloninger, C.R.The genetics and psychobiology of the seven factor model of personality. Silk, K.R.Biology of personality disorders. Washington (DC): American Psychiatric Press; 1998. 6392.Google Scholar
Cloninger, C.R., Przybeck, T.R., Svrakic, D.M., Wetzel, R.D.The Temperament and Character Inventory (TCI): A Guide to its development and use. Saint-Luis: Centre for Psychobiology and Personality; 1994.Google Scholar
Cloninger, C.R., Svrakic, D.M.Integrative psychobiological approach to assessment and treatment. Psychiatry 1997;60:120141.CrossRefGoogle ScholarPubMed
Cloninger, C.R., Svrakic, D.M., Przybeck, T.R.A psychobiological model of temperament and character. Arch Gen Psychiatry 1993;50:975990.CrossRefGoogle ScholarPubMed
Costa, P.T., McCrae, R.R. Jr.The Neo-Personality Inventory Manual. Odessa: Psychological Assessment Resources; 1985.Google Scholar
Dinzeo, T.J., Docherty, N.M.Normal Personality Characteristics in Schizophrenia: A review of the literature involving the FFM. J Nerv Ment Dis 2007 (5)421429.Google ScholarPubMed
Ekelund, J., Lichtermann, D., Järvelin, M.R., Peltonen, L.Association between novelty seeking and the type 4 dopamine receptor gene in a large finish cohort sample. Am J Psychiatry 1999;156:14531455.Google Scholar
Eklund, M., Hansson, L., Bengtsson-Tops, A.The influence of temperament and character on functioning and aspects of psychological health among people with schizophrenia. Eur Psychiatry 2004;19:3441.CrossRefGoogle ScholarPubMed
Eysenck, H.J., Eysenck, S.B.G.Manual of the Eysenck Personality Questionnaire. London: Hodder and Stoughton; 1975.Google Scholar
Fassino, S., Abbate-Daga, G., Amianto, F., Leombruni, P., Boggio, S., Rovera, G.Temperament and Character Profile of Eating Disorders: A Controlled Study with the Temperament and Character Inventory. Int J Eat Disord 2002;32:412425.CrossRefGoogle ScholarPubMed
Guillem, F., Bicu, M., Semkovska, M., Debruille, B.The dimensional symptom structure of schizophrenia and its association with temperament and character. Schizophr Res 2002;56:137147.CrossRefGoogle ScholarPubMed
Haapea, M., Miettunen, J., Läärä, E., Joukamaa, M.I., Järvelin, M.R., Isohanni, M.K.et al. Non-participation in a field survey with respect to psychiatric disorders. Scand J Public Health 2008;36:728736.CrossRefGoogle Scholar
Haapea, M., Miettunen, J., Veijola, J., Lauronen, E., Tanskanen, P.Isohanni. Non-participation may bias the results of a psychiatric survey. An analysis from the survey including magnetic resonance imaging within the Northern Finland 1966 Birth Cohort. Soc Psychiatry Psychiatr Epidemiol 2007;42:403409.CrossRefGoogle ScholarPubMed
Hansenne, M.P300 and personality: an investigation with the Cloninger´s Model. Biol Psychiatry 1999;50:143155.CrossRefGoogle ScholarPubMed
Hansenne, M., Reggers, J., Pinto, E., Kjiri, K., Ajamier, A., Ansseau, M.Temperament and character inventory (TCI) and depression. J Psychiatr Res 1999 33(1)3136.CrossRefGoogle ScholarPubMed
Hansson, L., Eklund, M., Bengtsson-Tops, A.The relationship of personality dimensions as measured by the TCI and quality of life in individuals with schizophrenia or schizoaffective disorder living in the community. Qual Life Res 2001;10:133139.CrossRefGoogle ScholarPubMed
Hellerstein, D.J., Kocsis, J.H., Chapman, D., Stewart, J.W., Harrison, W.Double-blind versus comparison of sertraline, imipramine, and placebo in the treatment of dysthymia: effects on personality. Am J Psychiatry 2000;157:14361444.CrossRefGoogle Scholar
Heresco-Levy, U., Javitt, D.C., Ermilov, M., Mordel, C., Silipo, G., Lichtenstein, M.Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999 56(1)2936.CrossRefGoogle ScholarPubMed
Herrán, A., Sierra-Biddle, D., Cuesta, M.J., Sandoya, M., Vázquez-Barquero, J.L.Can personality traits help us explain disability in chronic schizopnernia?. Psychiatry Clin Neurosci 2006 60(5)538545.CrossRefGoogle Scholar
Hettema, J.M., Prescott, C.A., Kendler, K.S.Genetic and environmental sources of covariation between generalized anxiety disorder and neuroticism. Am J Psychiatry 2004;161:15811587.CrossRefGoogle ScholarPubMed
Hori, H., Noguchi, H., Hashimoto, R., Nakabayashi, T., Saitoh, O., Murray, R.M.et al. Personality in schizophrenia assessed with the Temperament and Character Inventory (TCI). Psychiatry Res 2008 160(2)175183.CrossRefGoogle Scholar
Huppert, J.D., Smith, T.E., Apfeldorf, W.J.Use of self-report measures of anxiety and depression in outpatients with schizophrenia: reliability and validity. J Psychopathol Behave Assess 2002;24:275283.CrossRefGoogle Scholar
Isohanni, M., Jones, P.B., Moilanen, K., Rantakallio, P., Veijola Oja, H., Koiranen, M.et al. Early developmental milestones in adult schizophrenia and other psychoses. A 31-year follow-up of the Northern Finland 1966 Birth Cohort. Schizophr Res 2001;52:119.CrossRefGoogle ScholarPubMed
Kay, S.R., Fiszbein, A., Opler, L.A.The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1998;13:261276.CrossRefGoogle Scholar
Kendler, K.S., Kuhn, J., Prescott, C.A.The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depression. Am J Psychiatry 2004;161:631636.CrossRefGoogle ScholarPubMed
Kentros, M., Smith, T.E., Hull, J., McKee, M., Terkelsen, K., Capalbo, C.Stability of personality traits in schizophrenia and schizoaffective disorder: A pilot project. J Nerv Ment Dis 1997;185:549555.CrossRefGoogle ScholarPubMed
Kentros, M., Terkelsen, K., Hull, J., Smith, T.E., Goodman, M.The relationship between personality and quality of life in persons with schizoaffective disorder and schizophrenia. Qual Life Res 1997;6:118122.CrossRefGoogle Scholar
Kirkpatrick, B., Buchanan, R.W., Ross, D.E., Carpenter, W.T. Jr.A separate disease within the syndrome of schizophrenia. Arch Gen Psychiatry 2001;58:165171.CrossRefGoogle ScholarPubMed
Kirmayer, J.L., Robbins, J.M., Paris, J.Somatoform disorders: personality and the social matrix of somatic distress. J Abnorm Psychol 1994;103:125136.CrossRefGoogle ScholarPubMed
Lauronen, E., Koskinen, J., Veijola, J., Miettunen, J., Jones, P.B., Fenton, W.S.et al. Recovery from schizophrenic psychoses within the Northern Finland 1966 Birth Cohort. J Clin Psychiatry 2005;66:375383.CrossRefGoogle ScholarPubMed
Lauronen, E., Miettunen, J., Veijola, J., Karhu, M., Jones, P.B., Isohanni, M.Outcome and its predictors in schizophrenia within the Northern Finland 1966 Birth Cohort. Eur Psychiatry 2007;22:129136.CrossRefGoogle ScholarPubMed
Lichtermann, D., Ekelund, J., Peltonen, L., Järvelin, M.R.Genetic Architecture of temperament. Am J Psychiatry 2001;158:1339.CrossRefGoogle ScholarPubMed
Lysaker, P.H., Bell, M.D., Kaplan, E., Bryson, G.Personality and psychosocial dysfunction in schizophrenia: the association of extraversion and neuroticism to deficits in work performance. Psychiatry Res 1998;27:6168.CrossRefGoogle Scholar
Lysaker, P.H., Bell, D.B., Kaplan, E., Greigt, T.C., Bryson, G.Personality and psychosocial dysfunction in schizophrenia: The association between personality traits and symptoms. Psychiatry 1999;62:3648.CrossRefGoogle Scholar
Lysaker, P.H., Taylor, A.Personality dimensions in schizophrenia. Associations with symptoms and coping concurrently and 12 months later. Psychopathology 2007;40:338344.CrossRefGoogle ScholarPubMed
Lysaker, P.H., Wilt, M.A., Plascak-Hallberg, C.D., Brenner, C.A., Clements, C.A.Personality dimensions in schizophrenia: associations with symptoms and coping. J Nerv Ment Dis 2003;191:8086.CrossRefGoogle ScholarPubMed
Miettunen, J., Kantojarvi, L., Ekelund, J., Veijola, J., Karvonen, J.T., Peltonen, L.et al. A large population cohort provides normative data for investigation of temperament. Acta Psychiatr Scand 2004;110:150157.CrossRefGoogle ScholarPubMed
Milev, P., Ho, B.C., Arndt, S., Andreasen, N.C.Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up. Am J Psychiatry 2005;162:495506.CrossRefGoogle ScholarPubMed
Ram, R., Bromet, E.J., Eaton, W.W., Pato, C., Schwarzt, J.E.The natural course of schizophrenia: a review of first admission studies. Schizophr Bull 1992;18:185207.CrossRefGoogle ScholarPubMed
Ridler, K., Veijola, J., Tanskanen, P., Haapea, M., Miettunen, J., Pyhtinen, J.et al. Infant motor development, adult cognition and fronto-cerebellar circuitry: different developmental trajectories in normals and schizophrenic persons within the Northern Finland 1966 Birth Cohort. Proc Natl Acad Sci U S A 2006 17(103)1565115656.CrossRefGoogle Scholar
Roberts, S.B., Kendler, K.S.Neuroticism and self-esteem as indices of the vulnerability to major depression in women. Psychol Med 1999;29:11011109.CrossRefGoogle ScholarPubMed
Spitzer, RL, Gibbon, M, Endicott, J.Global Assessment Scale (GAS), Global Assessment of Functioning (GAF) scale, Social and Occupational Functioning Assessment Scale (SOFAS). In: American Psychiatric Association. Handbook of psychiatric measures. Washington: American Psychiatric Association, 2000.Google Scholar
Spitzer, R.L., Williams, J.B.W., Gibbon, M.et al. Structured Clinical Interview for DSM-III-R Patient Edition (SCID-P, 9/1/89 Version). New York, NY: Biometrics Research Department, New York State Psychiatric Institute; 1989.Google Scholar
Stompe, T., Willinger, U., Fischer, G., Meszaros, K., Berger, P., Strobl, R.et al. The unified biosocial model of personality in schizophrenia families and controls. Psychopathology 1998;31:4551.CrossRefGoogle ScholarPubMed
Sugiura, M., Kawashima, R., Nakagawa, M., Okada, K., Sato, T., Goto, R.et al. Correlation between human personality and neural activity in cerebral cortex. Neuroimage 2000;11:541546.CrossRefGoogle ScholarPubMed
Svrakic, D.M., Draganic, K., Hill, C., Bayon, T.R., Przybeck, T.R., Cloninger, C.R.Temperament, Character, and personality disorders: etiologic, diagnostic and treatment issues. Acta Psychiatrica Scandinavica 2002;3:189195.CrossRefGoogle Scholar
Tanskanen, P., Veijola, J., Piippo, U., Haapea, M., Miettunen, J., Pyhtinen, J.et al. Hippocampus and amygdala volumes in schizophrenia and other psychoses in the Northern Finland 1966 Birth Cohort. Schizophr Res 2005;75:283294.CrossRefGoogle ScholarPubMed
Torgalsboen, A.K.Comorbidity in schizophrenia: a prognostic study of personality disorder in recovered and non-recovered schizophrenia patients. Scand J Psychol 1999;40:147152.CrossRefGoogle ScholarPubMed
Van Ammers, E.C., Sellman, J.D., Mulder, R.T.Temperament and substance abuse in schizophrenia: is there a relationship?. J Nerv Ment Dis 1997;185:283288.CrossRefGoogle ScholarPubMed
Van Os, J., Jones, P.B.Neuroticism as a risk factor for schizophrenia. Psychol Med 2001;31:11291134.CrossRefGoogle Scholar
Zuckerman, M.Good and bad humors: Biochemical base of personality and its disorders. Psychol Sci 1995;6:325332.CrossRefGoogle Scholar
Zuckerman, M., Cloninger, C.R.The relationship between Cloninger's. Zuckerman's and Eysenck's dimensions of personality. Person individual Diff 1996;21:283285.CrossRefGoogle Scholar
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