Skip to main content Accessibility help
×
Home

Article contents

1694 – Treatment Of Psychotic Episode In Epilepsy - Olanzapine Vs Risperidone

Published online by Cambridge University Press:  15 April 2020


D. Ravanic
Affiliation:
Psyciatric Clinic, Serbia
S. Djukic Dejanovic
Affiliation:
Psyciatric Clinic, Serbia
D. Ristic Ignjatovic
Affiliation:
Psyciatric Clinic, Serbia
M. Ilic
Affiliation:
Pathology, Medical Faculty, Serbia
M. Borovcanin
Affiliation:
Psyciatric Clinic, Serbia
S. Babic
Affiliation:
Psyciatric Clinic, Clinical Center Kragujevac, Kragujevac, Serbia
M. Jovanovic
Affiliation:
Psyciatric Clinic, Serbia

Get access

Abstract

Purpose

It is known that antipsychotic lower seizure threshold, cause EEG abnormalities and put the patients in the risk for additional seizures. Due to changes in organic substrate, psychosis is very common comorbidity in epilepsy. There is no consensus about treatment options. The purpose of this research was to compare effects of risperidone and olanzapine in treatment of psychotic episode in verified Grand-mall epilepsy. Treatment with bout antipsychotic was parallel.

Methods

Psychotic episode in 100 adults (67 males) with epilepsy, Grand-mall type, were measured with BPRS scale. History of diagnosis of epilepsy, Grand-mall type was verified clinically and by EEG. Subject were treated either with olanzapine (n=53) 14.7±2.4 mg per day or with risperidone (n=47) 8.6±3.8 mg per day, orally.

Results

The total BPRS scores in olanzapine group at baseline, in 1st, 2nd and 3rd week were 139.6±34.2, 91.3±21.4, 81.5±19.8, and 72.3±11.1, respectively (p< 0.05). The total BPRS scores in risperidone group at baseline, in 1st, 2nd and 3rd week were 137.1±32.4, 101.6±30.9, 98.4±26.6, and 90.3±19.1, respectively (p< 0.05).

Conclusions

Results of our research showed that risperidone is more effective and comfortable drug than olanzapine in the treatment of psychotic episodes in epilepsy.


Type
Other
Copyright
Copyright © European Psychiatric Association 2013

Access options

Get access to the full version of this content by using one of the access options below.
Submit a response

Comments

No Comments have been published for this article.

Full text views

Full text views reflects PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.

Total number of HTML views: 0
Total number of PDF views: 1 *
View data table for this chart

* Views captured on Cambridge Core between 15th April 2020 - 3rd December 2020. This data will be updated every 24 hours.

Hostname: page-component-79f79cbf67-b9sxz Total loading time: 0.246 Render date: 2020-12-03T02:12:55.217Z Query parameters: { "hasAccess": "0", "openAccess": "0", "isLogged": "0", "lang": "en" } Feature Flags last update: Thu Dec 03 2020 02:07:24 GMT+0000 (Coordinated Universal Time) Feature Flags: { "metrics": true, "metricsAbstractViews": false, "peerReview": true, "crossMark": true, "comments": true, "relatedCommentaries": true, "subject": true, "clr": false, "languageSwitch": true }

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

1694 – Treatment Of Psychotic Episode In Epilepsy - Olanzapine Vs Risperidone
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

1694 – Treatment Of Psychotic Episode In Epilepsy - Olanzapine Vs Risperidone
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

1694 – Treatment Of Psychotic Episode In Epilepsy - Olanzapine Vs Risperidone
Available formats
×
×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *