Skip to main content Accessibility help
×
Home

The effect of lidocaine and sufentanil in preventing intraocular pressure increase due to succinylcholine and endotracheal intubation

  • H. A. Moeini (a1), H. A. Soltani (a2), A. R. Gholami (a2) and H. Masoudpour (a1)

Abstract

Summary

Background and objective: Succinylcholine administration, laryngoscopy and tracheal intubation are followed by increased intraocular pressure. Various premedications have been advocated for preventing increases in intraocular pressure, especially in patients undergoing surgical repair of open globe due to penetrating eye trauma. Results of studies in this area have been controversial. Methods: In this double-blind study, three groups of 70 patients receiving sufentanil, lidocaine and placebo 90 s prior to intubation were evaluated and compared for intraocular pressure changes following succinylcholine administration, laryngoscopy and tracheal intubation. Results: Mean intraocular pressure measured 2 and 3 min after succinylcholine administration in groups receiving sufentanil and lidocaine was significantly lower than in the placebo group. Mean intraocular pressure changes in the three groups were −1.84, −2.03 and +2.82 mmHg, respectively in minute 2; −4.78, −4.73 and +1.35 mmHg, respectively in minute 5. There was a significant intraocular pressure decrease in the sufentanil and lidocaine groups, compared to the placebo group. The eye surgeons' satisfaction was also significantly higher with the sufentanil and lidocaine groups. Conclusion: Previous studies have yielded controversial results as to the effect of sufentanil and lidocaine in preventing intraocular pressure following succinylcholine administration, laryngoscopy and tracheal intubation. The present study affirms the preventive effect of these drugs on intraocular pressure increase.

Copyright

Corresponding author

Correspondence to: Hassan Masoudpour, N 12, Dr Masoudpour alley, Jomhori Square, Isfahan, Iran. E-mail: Masoudpour@yahoo.com; Tel: +98 311 3357769; Fax: +98 311 3358628

References

Hide All

References

Miller RD. Miller's Anesthesia, 6th edn.Churchill Livingstone, 2005, Chapter 65: 490491; 25312537.
Cunningham AJ, Barry P. Intraocular pressure-physiology and implications for anaesthetic management. Can J Anaesth 1986; 33: 195.
Wynands JF, Cromwell DF. Intra-ocular tension in association with succinylcholine and endotracheal intubation. Can Anaesth Soc J 1960; 7: 3943.
Donlon JrJV. Anesthesia for ophthalmic surgery. In: Barash P, ed. ASA Refresher Course Lectures, Vol. 16.Philadelphia: JB Lippincott, 1988: 81.
Murphy DF. Anesthesia and intraocular pressure. Anesth Analg 1985; 64 (5): 520530.
Hall SC, Lerman J. Should succinylcholine be used in the child with an open eye injury and full stomach? Anesth Rev 1993; 20 (3): 98.
Badrinath SK, Braverman B, Ivankovich AD. Alfentanil and sufentanil prevent the increase in IOP from succinylcholine and intubation. Anesth Analg 1988; 67: S5.
Ghignone M, Noe C, Calvillo Oet al. Anesthesia for ophthalmic surgery in the elderly: the effects of clonidine on intraocular pressure, perioperative hemodynamics, and anesthetic requirement. Anesthesiology 1988; 68 (5): 707716.
Mahajan RP, Grover V, Sharma SL, Singh H. Intranasal nitroglycerin and intraocular pressure during general anesthesia. Anesth Analg 1988; 67 (7): 631636.
Smith RB, Babinski M, Leano N. The effect of lidocaine on succinylcholine-induced rise in intraocular pressure. Can Anaesth Soc J 1979; 26 (6): 482483.
Kruger AE, Roelofse JA. Precautions against intra-ocular pressure changes during endotracheal intubation – a comparison of pretreatment with intravenous lignocaine and diazepam. S Afr Med J 1983; 63 (23): 887888.
Lerman J, Kiskis AA. Lidocaine attenuates the intraocular pressure response to rapid intubation in children. Can Anaesth Soc J 1985; 32 (4): 339345.
Murphy DF, Eustace P, Unwin A, Magner JB. Intravenous lignocaine pretreatment to prevent intraocular pressure rise following suxamethonium and tracheal intubation. Br J Ophthalmol 1986; 70 (8): 596598.
Grover VK, Lata K, Sharma S, Kaushik S, Gupta A. Efficacy of lignocaine in the suppression of the intra-ocular pressure response to suxamethonium and tracheal intubation. Anaesthesia 1989; 44 (1): 2225.
Abdulla WY, Flaifil HA. Intraocular pressure changes in response to endotracheal intubation facilitated by atracurium or succinylcholine with or without lidocaine. Acta Anaesthesiol Belg 1992; 43 (2): 91101.
Nunez M, Figueira Aet al. Comparative study of clonidine and lidocaine on the attenuation of the intraocular pressure increase associated with laryngoscopy and endotracheal intubation. Rev Esp Anestesiol Reanim 1995; 42 (8): 312315.
Jantzen JP. [Anesthesia and intraocular pressure]. Anaesthesist 1988 August; 37 (8): 458469 (Review), German.
Kay B, Nolan D, Mayall R, Healy TE. The effect of sufentanil on the cardiovascular responses to tracheal intubation. Anaesthesia 1987; 42 (4): 382386.
Polarz H, Bohrer H, Fleischer Fet al. Effects of thiopentone/suxamethonium on intraocular pressure after pretreatment with alfentanil. Eur J Clin Pharmacol 1992; 43 (3): 311313.
Polarz H, Böhrer H, Martin Eet al. Oral clonidine premedication prevents the rise in intraocular pressure following succinylcholine administration. Ger J Ophthalmol 1993; 2 (2): 9799.
Kovac AL, Bennets PS, Ohara Set al. Effect of esmolol on hemodynamics and intraocular pressure response to succinylcholine and intubation following low-dose alfentanil premedication. J Clin Anesth 1992; 4 (4): 315320.
Indu B, Batra YK, Puri GDet al. Nifedipine attenuates the intraocular pressure response to intubation following succinylcholine. Can J Anaesth 1989; 36: 269272.
Alexander R, Hill R, Lipham WJ, Weatherwax KJ, El-Moalem HE. Remifentanil prevents an increase in intraocular pressure after succinylcholine and tracheal intubation. Br J Anaesth 1998; 81: 606607.
Zimmerman AA, Funk KJ, Tidwell JL. Propofol and alfentanil prevent the increase in intraocular pressure caused by succinylcholine and endotracheal intubation during a rapid sequence induction of anesthesia. Anesth Analg 1996; 83 (4): 814817.

Keywords

Related content

Powered by UNSILO

The effect of lidocaine and sufentanil in preventing intraocular pressure increase due to succinylcholine and endotracheal intubation

  • H. A. Moeini (a1), H. A. Soltani (a2), A. R. Gholami (a2) and H. Masoudpour (a1)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.