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Effect of intra-operative mechanical ventilation using 50% inspired oxygen on pulmonary oxygenation

Published online by Cambridge University Press:  16 August 2006

C. Lentschener
Affiliation:
Department of Anaesthesiology, Hôpital Antoine B´clère, Universit´ Paris Sud, 157, rue de la Porte de Trivaux, 92141 Clamart Cedex, France
D. Benhamou
Affiliation:
Department of Anaesthesiology, Hôpital Antoine B´clère, Universit´ Paris Sud, 157, rue de la Porte de Trivaux, 92141 Clamart Cedex, France
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Abstract

Forty-three ASA Grade I patients scheduled for elective abdominal surgery received at random either 25% or 50% inspired oxygen for intra-operative mechanical ventilation lasting 4–6 h. Pulse oximetry was monitored continuously. Venous admixture was assessed from the PaO2/FIO2 ratio and was measured twice intra-operatively: at the time of incision, and during surgical wound closure. PaO2 was measured 1 h after extubation having breathed room air for 10 min, if tolerated. The patients in the two groups were similar in regard to general characteristics, and had similar operations. Patients given oxygen 50% had operations that lasted longer, which made the trial more sensitive. The inspired oxygen did not affect pulmonary gas exchange either within each group or between groups under the conditions of the study. In no patient did pulse oximetry record an oxygen saturation below 95% intra-operatively.

Type
Original Article
Copyright
1997 European Society of Anaesthesiology

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