Addington, J, Coldham, EL, Jones, B, Ko, T and Addington, D (2003) The first episode of psychosis: the experience of relatives. Acta Psychiatrica Scandinavia 108, 285–289.
Alvarez-Jiménez, M, Gleeson, JF, Cotton, SM, Wade, D, Crisp, K, Yap, MB, McGorry, PD (2010) Differential predictors of critical comments and emotional over-involvement in first-episode psychosis. Psychological Medicine 40, 63–72.
Awad, AG and Voruganti, LNP (2008) The burden of schizophrenia on caregivers – a review. Pharmacoeconomics 26, 149–162.
Barrowclough, C and Hooley, JM (2003) Attributions and expressed emotion: a review. Clinical Psychology Review 23, 849–880.
Bebbington, P and Kuipers, L (1994) The predictive utility of EE in schizophrenia: an aggregate analysis. Psychological Medicine 24, 707–718.
Bendall, S, Alvarez-Jimenez, M, Hulbert, CA, McGorry, PD and Jackson, HJ (2012) Childhood trauma increases the risk of posttraumatic stress disorder in response to first-episode psychosis. Australian and New Zealand Journal of Psychiatry 46, 35–39.
Bentsen, H, Notland, TH, Boye, B, Munkvold, OG, Bjorge, H, Lersbryggen, AB, Uren, G, Oskarsson, KH, Berg-Larsen, R, Lingjaerde, O and Malt, UF (1998) Criticism and hostility in relatives of patients with schizophrenia or related psychoses: demographic and clinical predictors. Acta Psychiatrica Scandinavica 97, 76–85.
Bifulco, A, Brown, GW and Harris, TO (1994) The childhood experience of care and abuse. Journal of Child Psychology and Psychiatry 35, 1419–1435.
Boydell, J, Onwumere, J, Dutta, R, Bhavsar, V, Hill, N, Morgan, C, Dazzan, P, Morgan, K, Pararajan, M, Kuipers, E, Jones, P, Murray, R and Fearon, P (2014) Caregiving in first-episode psychosis: social characteristics associated with perceived ‘burden’ and associations with compulsory treatment. Early Intervention in Psychiatry 8, 122–129.
Brown, S and Birtwistle, J (1998) People with schizophrenia and their families. Fifteen-year outcome. British Journal of Psychiatry 173, 139–144.
Burns, T and Firn, M (2002) Assertive Outreach in Mental Health. A Manual for Practitioners. Oxford: Oxford University Press.
Campbell, MK, Piaggio, G, Elbourne, DR, Altman, DG and CONSORT Group (2012) Consort 2010 statement: extension to cluster randomised trials. BMJ 345, e5661.
Cechnicki, A, Bielańska, A, Hanuszkiewicz, I and Daren, A (2013) The predictive validity of Expressed Emotions (EE) In schizophrenia. A 20-year prospective study. Journal of Psychiatric Research 47, 208–214.
Chandra Kashyap, G and Kant Sing, S (2017) Reliability and validity of general health questionnaire (GHQ12) for male tannery workers: a study carried out in Kanpur, India. BMC Psychiatry 17, 102.
Cole, JD and Kazarian, SS (1988) The level of expressed emotion scale. A new measure of expressed emotion. Journal of Clinical Psychology 44, 392–397.
Cole, JD and Kazarian, SS (1993) Predictive validity of the Level of Expressed Emotion (LEE) Scale: readmission follow-up data for 1, 2, and 5-year periods. Journal of Clinical Psychology 49, 216–218.
Cotton, SM, McCann, TV, Gleeson, JF, Crisp, K, Murphy, BP and Lubman, DI (2013) Coping strategies in carers of young people with first episode psychosis. Schizophrenia Research 146, 118–124.
Domínguez-Martínez, T, Medina-Pradas, C, Kwapil, TR and Barrantes-Vidal, N (2014) Relatives’ illness attributions mediate the association of expressed emotion with early psychosis symptoms and functioning. Psychiatry Research 218, 48–53.
Ferrannini, L, Ghio, L, Gibertoni, D, Lora, A, Tibaldi, G, Neri, G, Piazza, A and Italian Mental Health Data Group (2014) Thirty-five years of community psychiatry in Italy. The Journal of Nervous and Mental Disease 202, 432–439.
Fleischhacker, WW, Arango, C, Arteel, P, Barnes, TRE, Carpenter, W, Duckworth, K, Galderisi, S, Halper, L, Knapp, M, Marden, SR, Moller, M, Sartorius, N and Woodruff, P (2014) Schizophrenia – time to commit to policy change. Schizophrenia Bulletin 40(Suppl. 3),S165–S194 doi: 10.1093/schbul/sbu00.
Galletly, C, Castle, D, Dark, F, Humberstone, V, Jablensky, A, Killackey, E, Kulkarni, J, McGorry, P, Nielssen, O and Tran, N (2016) Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the management of schizophrenia and related disorders. Australian and New Zealand Journal of Psychiatry 50, 410–472.
Garety, P and Rigg, A (2001) Early psychosis in the inner city: a survey to inform service planning. Social Psychiatry and Psychiatric Epidemiology 36, 537–544.
Garety, PA, Fowler, DG, Freeman, D, Bebbington, P, Dunn, G and Kuipers, E (2008) Cognitive behavioural therapy and family intervention for relapse prevention and symptom reduction in psychosis: randomised controlled trial. British Journal of Psychiatry 192, 412–423.
Goldberg, D and Williams, P (1988) A User's Guide to the General Health Questionnaire. Windsor, UK: NFER-Nelson.
Goldberg, DP, Gater, R, Sartorius, N, Ustun, TB, Piccinelli, M, Gureje, O and Rutter, C. (1997) The validity of two versions of the GHQ in the WHO study of mental illness in general health care. Psychological Medicine 27, 191–197.
Gonclaves-pereira, M, Xavier, M, van Wijngaarden, B, Papoila, AL, Schene, AH and Caldas-de-Almedia, JM (2013) Impact of psychosis on Portuguese caregivers: a cross cultural explanation of burden, distress, positive aspects and clinical-functional correlates. Social Psychiatry and Psychiatric Epidemiology 48, 325–335.
Graetz, B (1991) Multidimensional properties of the General Health Questionnaire. Social Psychiatry and Psychiatric Epidemiology 26, 132–138.
Gupta, S, Isherwood, G, Jones, K and Van Impe, K (2015) Assessing health status in informal schizophrenia caregivers compared with health status in non-caregivers and caregivers of other conditions. BMC Psychiatry 15, 162.
Haidl, T, Rosen, M, Schultze-Lutter, F, Nieman, D, Eggers, S, Heinimaa, M, Juckel, G, Heinz, A, Morrison, A, Linszen, D, Salokangas, R, Klosterkötter, J, Birchwood, M, Patterson, P, Ruhrmann, S; European Prediction of Psychosis Study (EPOS) Group (2018) Expressed emotion as a predictor of the first psychotic episode - Results of the European prediction of psychosis study. Schizophrenia Research 199, 346–352.
Harvey, C, Lewis, J and Farhall, J (2018) Receipt and targeting of evidence-based psychosocial interventions for people living with psychoses: findings from the second Australian national survey of psychosis. Epidemiology and Psychiatric Sciences. doi: 10.1017/S2045796018000288.
Hayes, L, Hawthorne, G, Farhall, J, O'Hanlon, B and Harvey, C (2015) Quality of life and social isolation among caregivers of adults with schizophrenia: policy and outcomes. Community Mental Health Journal 51, 591–597.
Hesse, K, Kriston, L, Mehl, S, Wittorf, A, Wiedemann, W, Wolwer, W and Klingberg, S (2016) The vicious cycle of family atmosphere, interpersonal self-concepts and paranoia in schizophrenia- a longitudinal study. Schizophrenia Bulletin 41, 1403–1412.
Jansen, JE, Gleeson, J and Cotton, S (2015 a) Towards a better understanding of caregiver distress in early psychosis: a systematic review of the psychological factors involved. Clinical Psychology Review 35, 56–66.
Jansen, JE, Haahr, UH, Harder, S, Trauelsen, AM, Lyse, HG, Pedersen, MB and Simonsen, E (2015 b) Caregiver distress in first-episode psychosis: the role of subjective appraisal, over-involvement and symptomatology. Social Psychiatry Psychiatric Epidemiology 50, 371–378.
Kay, SR, Fiszbein, A and Opler, LA (1987) The positive and negative syndrome scale for schizophrenia. Schizophrenia Bulletin 13, 261–276.
Kirkbride, JB, Errazuriz, A, Croudace, TJ, Morgan, C, Jackson, D, McCrone, P and Murray, RM (2012) Systematic review of the incidence and prevalence of schizophrenia and other psychoses in England. Department of Health Policy Research Programme.
Koutra, K, Trilivac, S, Roumeliotaki, T, Basta, M, Simos, P, Lionis, C and Vgontzas, AN (2015) Impaired family functioning in psychosis and its relevance to relapse: a two-year follow-up study. Comprehensive Psychiatry 62, 1–12.
Kraemer, HC, Wilson, GT, Fairburn, CG and Agras, WS (2002) Mediators and moderators of treatment effects in randomized clinical trials. Archives of General Psychiatry 59, 877–883.
Kreyenbuhl, J, Buchanan, RW, Dickerson, FB and Dixon, LB (2010) The Schizophrenia Patient Outcomes Research Team (PORT): updated treatment recommendations 2009. Schizophrenia Bulletin 36, 94–103.
Kuipers, E and Bebbington, P (2005) Research on Burden and Coping Strategies in families of people with mental disorders: problems and perspectives. Chapter 10, pp. 217–234. In Sartorius, N, Leff, J, L'opez-Ibor, JJ, Maj, M & Okasha, A (eds), Families and Mental Disorders: From Burden to Empowerment. London: John Wiley & Sons.
Kuipers, E and Raune, D (2000) The early development of expressed emotion and burden in the families of first onset psychosis. In Birchwood, M, Fowler, D and Jackson, C (eds), Early Intervention in Psychosis. Chichester: Wiley, pp. 128–140.
Kuipers, E, Fowler, D, Garety, P, Chisolm, D, Freeman, D, Dunn, G, Bebbington, P and Hadley, C (1998) London-east Anglia randomised controlled trial of cognitive-behavioural therapy for psychosis. III: follow-up and economic evaluation at 18 months. British Journal of Psychiatry 173, 61–68.
Kuipers, E, Leff, J and Lam, D (2002) Family Work for Schizophrenia: A Practical Guide. London: Gaskell.
Lasalvia, A, Bonetto, C, Lenzi, J, Rucci, P, Lozzino, L, Cellini, M et al. (2017) Predictors and moderators of treatment outcome in patients receiving multi-element psychosocial intervention for early psychosis. Results from the Get UP pragmatic cluster randomized controlled trial. The British Journal of Psychiatry 210, 342–349.
Lavis, A, Lester, H, Everard, L, Freemantle, N, Amos, T, Fowler, D, Hodgekins, J, Jones, P, Marshall, M, Sharma, V, Larsen, J, McCrone, P, Singh, S, Smith, J and Birchwood, M (2015) Layers of listening: qualitative analysis of the impact of early intervention services for first episode psychosis on carers’ experiences. The British Journal of Psychiatry 207, 135–142.
Lee, G, Barrowclough, C and Lobban, F (2014) Positive affect in the family environment protects against relapse in first-episode psychosis. Social Psychiatry and Psychiatric Epidemiology 49, 367–376.
Lobban, F, Postlethwaite, A, Glentworth, D, Pinfold, V, Wainwright, L, Dunn, G, Clancy, A and Haddock, G (2013) A systematic review of randomised controlled trials of interventions reporting outcomes for relatives of people with psychosis. Clinical Psychology Review 33, 372–382.
Marwaha, S, Thompson, A, Upthegrove, R and Broome, MR (2016) Fifteen years on- early intervention for a new generation. The British Journal of Psychiatry 209, 186–188.
McCann, TV, Lubman, DI and Clark, E (2011) First-time primary caregivers’ experience of caring for young adults with first-episode psychosis. Schizophrenia Bulletin 37, 381–388.
McNab, C, Haslam, N and Burnett, P (2007) Expressed emotion, attributions, utility beliefs and distress in parents of young people with first episode psychosis. Psychiatry Research 15, 97–106.
Mueser, KT, Penn, DL, Addington, J, Brunette, MF, Gingerich, S, Glynn, SM, Lynde, DW, Gottlieb, JD, Meyer-Kalos, P, McGurk, SR, Cather, C, Saade, S, Robinson, DG, Schooler, NR, Rosenheck, RA and Kane, JM (2015) The NAVIGATE program for first episode psychosis: rationale, overview and description of psychosocial components. Psychiatry Services 66, 680–690.
National Institute for Health and Care Excellence (2014) Psychosis and Schizophrenia in Adults: Treatment and Management. . London: NICE.
Norman, RMG, Malla, AK, Manchanda, R, Harricharan, R, Takhar, J and Northcott, SS (2005) Social support and three-year symptom and admission outcomes for first episode psychosis. Schizophr Research 80, 227–234.
Norman, R, Lecomte, T, Addington, D and Anderson, E (2017) Canadian treatment guidelines on psychosocial treatment of schizophrenia in adults. Canadian Journal of Psychiatry/La Revue Canadienne de Psychiatrie 62, 617–623.
Onwumere, J, Kuipers, E, Bebbington, P, Dunn, G, Fowler, D, Freeman, D, Watson, P and Garety, P (2008) Care-giving and illness beliefs in the course of psychotic illness. Canadian Journal of Psychiatry 53, 460–468.
Onwumere, J, Kuipers, E, Bebbington, P, Dunn, G, Freeman, D, Fowler, D and Garety, P (2009) Patient perceptions of caregiver criticism in psychosis: links with patient and caregiver functioning. The Journal of Nervous and Mental Disease 197, 85–91.
Onwumere, J, Lotey, G, Schulz, J, James, G, Afsharzadegan, R, Harvey, R, Chu Man, L, Kuipers, E and Raune, D (2017) Burnout in early course psychosis caregivers: the role of illness beliefs and coping styles. Early Intervention in Psychiatry 11, 237–243.
Parker, G, Tupling, H and Brown, LB (1979) A parental bonding instrument. British Journal of Medical Psychology 52, 1–10.
Patel, M, Chawla, R, Krynicki, CR, Rankin, P and Upthgrove, R (2014) Health beliefs and carer burden in first episode psychosis. BMC Psychiatry 14, 171. doi: 10.1186/1471-244X-14-171.
Patterson, P, Birchwood, M and Cochrane, R (2005) Expressed emotion as an adaptation to loss – prospective study in first-episode psychosis. British Journal of Psychiatry 187(Suppl. 48), S59–S64.
Penn, DL, Waldheter, EJ, Perkins, DO, Mueser, KT and Lieberman, JA (2005) Psychosocial treatment for first episode psychosis: a research update. American Journal of Psychiatry 162, 2220–2232.
Politi, PL, Piccinelli, M and Wilkinson, G (1994) Reliability, validity and factor structure of the 12-item General Health Questionnaire among young males in Italy. Acta Psychiatrica Scandinavica 90, 432–437.
Poon, AW, Harvey, C, Mackinnon, A and Joubert, L (2016) A longitudinal population-based study of carers of people with psychosis. Epidemiology and Psychiatric Sciences 5, 1–11.
Ran, MS, Chui, CHK, Wong, IY-L, Mao, WJ, Lin, FR, Liu, B and Chan, CLW (2016) Family caregivers and outcome of people with schizophrenia in rural China: 14 year follow up study. Social Psychiatry and Psychiatric Epidemiology 51, 513–520.
Raune, D, Kuipers, E and Bebbington, P (2004) Expressed emotion at first episode psychosis: investigating a carer appraisal model. British Journal of Psychiatry 184, 321–326.
Revier, CJ, Reininghaus, U, Dutta, R, Fearon, P, Murray, R, Doody, GA, Croudace, T, Dazzan, P, Heslin, M, Onyejiaka, A, Kravariti, E, Lappin, J, Lomas, B, Kirkbride, JB, Donoghue, K, Morgan, C and Jones, PB (2015) Ten-year outcomes of first-episode psychoses in the MRC AESOP-10 study. The Journal of Nervous and Mental Disease 203, 379–386.
Robinson, D, Woerner, MG, Alvir, JM, Bilder, R, Goldman, R, Geisler, S, Koreen, A, Sheitman, B, Chakos, M, Mayerhoff, D and Lieberman, JA (1999) Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Archives of General Psychiatry 56, 241–247.
Ruggeri, M, Bonetto, C, Lasalvia, A, De Girolamo, G, Fioritti, A, Rucci, P et al. (2012) A multi-element psychosocial intervention for early psychosis (GET UP PIANO TRIAL) conducted in a catchment area of 10 million inhabitants: study protocol for a pragmatic cluster randomized controlled trial. Trials 13, 73.
Ruggeri, M, Bonetto, C, Lasalvia, A, Fioritti, A, de Girolamo, G, Santonastaso, P et al. (2015) Feasibility and effectiveness of a multi-element psychosocial intervention for first-episode psychosis: results from the cluster-randomized controlled GET UP PIANO trial in a Catchment Area of 10 Million Inhabitants. Schizophrenia Bulletin 4, 1192–1203.
Ruggeri, M, Lasalvia, A, Santonastaso, P, Pileggi, F, Leuci, E, Miceli, M et al. (2017) Family burden, emotional distress and service satisfaction in first episode psychosis: a nine month follow up study comparing TAU and a multi element integrated intervention. Data from the Get UP Trial. Frontiers in Psychology 8, 721.
Sadath, A, Muralidhar, D, Varambally, S, Gangadhar, BN and Jose, JP (2017) Do stress and support matter for caring? The role of perceived stress and social support on expressed emotion of carers of persons with first episode psychosis. Asian Journal of Psychiatry 25, 163–168.
Stata Corp (2013) Stata Statistical Software: Release 13. College Station, TX: StataCorp LP.
Stowkowy, J, Addington, D, Liu, L, Hollowell, B and Addington, J (2012) Predictors of disengagement from treatment in an early psychosis program. Schizophrenia Research 136, 7–12.
Treanor, L, Lobban, F and Barrowclough, C (2013) Relatives responses to psychosis: an exploratory investigation of low expressed emotion relatives. Psychology and Psychotherapy 86, 197–211.
van Wijngaarden, B, Schene, AH, Koeter, MA, Vazquez-Barquero, JL, Knudsen, HC, Lasalvia, A, Mcrone, P and the Epsilon Study Group (2000) Caregiving in schizophrenia: development, internal consistency and reliability of the involvement evaluation questionnaire – European version. British Journal of Psychiatry 177, s21–s27.
Vasconcelos, ESD, Wearden, A and Barrowclough, C (2013) Expressed emotion, types of behavioural control and controllability attributions in relatives of people with recent-onset psychosis. Social Psychiatry and Psychiatric Epidemiology 48, 1377–1388.
Vaughn, CE and Leff, JP (1976) The measurement of expressed emotion in the families of psychiatric patients. British Journal of Social and Clinical Psychology 15, 157–165.
Velthorst, E, Fett, AKJ, Reichenberg, A, Perlman, G, van OS, J, Bromet, EJ and Kotov, R (2017) The 20 year longitudinal trajectories of social functioning in individuals with psychotic disorders. American Journal of Psychiatry 174, 1075–1085 Dx.doi.org/10.1176/appi.ajp.2016.15111419.
Von Polier, GG, Meng, H, Lambert, M, Strauss, M, Zarotti, G, Karle, M, Dubois, R, Stark, FM, Neidhart, S, Zollinger, R, Burgin, D, Felder, W, Resch, F, Koch, E, Schulte-Markwort, M and Schimmelmann, BG (2014) Patterns and correlates of expressed emotion, perceived criticism and rearing style in first admitted early onset schizophrenia spectrum disorders. The Journal of Nervous and Mental Disease 202, 783–787.
Werneke, U, Goldberg, DP, Yalcin, I and Ustun, BT (2000) The stability of the factor structure of the General Health Questionnaire. Psychological Medicine 30, 823–829.
World Health Organisation (1992) Schedules for Clinical Assessment in Neuropsychiatry (SCAN), Version 1.0. Geneva: World Health Organisation.