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Longitudinal imaging studies in schizophrenia: the relationship between brain morphology and outcome measures

Published online by Cambridge University Press:  11 April 2011

Marcella Bellani ,
Nicola Dusi  and
Paolo Brambilla
Marcella Bellani*
Affiliation:
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Verona (Italy) Inter-University Centre for Behavioural Neurosciences (ICBN), University of Verona, Verona and DPMSC, Section of Psychiatry, University of Udine, Udine (Italy)
Nicola Dusi
Affiliation:
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Verona (Italy) Inter-University Centre for Behavioural Neurosciences (ICBN), University of Verona, Verona and DPMSC, Section of Psychiatry, University of Udine, Udine (Italy)
Paolo Brambilla
Affiliation:
Inter-University Centre for Behavioural Neurosciences (ICBN), University of Verona, Verona and DPMSC, Section of Psychiatry, University of Udine, Udine (Italy) Scientific Institute ‘E. Medea’, Udine (Italy)
*
Address for correspondence: Dr. M. Bellani, Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, PiazzaleL. A. Scuro 10, 37134 Verona (Italy). Fax: +39–045–8027498 E-mail: marcella.bellani@univr.it
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Abstract

Imaging studies have tried to identify morphological outcome measures of schizophrenia in the last two decades. In particular, longitudinal studies have reported a correlation between larger ventricles, decreased prefrontal volumes and worse outcome. This would potentially allow to isolate subtypes of schizophrenia patients with a worse prognosis and more evident biological impairments, ultimately helping in designing specific rehabilitation interventions.

Keywords

outcome assessmentschizophrenialongitudinal studiesmagnetic resonance.
Type
Neurobiology of Psychosis. Clinical and Psychosocial Implications
Information
Epidemiology and Psychiatric Sciences , Volume 19 , Issue 3 , September 2010 , pp. 207 - 210
Copyright
Copyright © Cambridge University Press 2010

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References

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