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Symptoms and social functioning features in chronic schizophrenia are aggregate in a tripartite structure

Published online by Cambridge University Press:  11 October 2011

Vittorio Di Michele
Affiliation:
Azienda USL di Pescara, Dipartimento di Salute Mentale, Centro di Salute Mentale di Pescara, Pescara
Francesca Bolino
Affiliation:
Azienda USL di Pescara, Dipartimento di Salute Mentale, Centro di Salute Mentale di Pescara, Pescara
Gabriella Di Zio
Affiliation:
Azienda USL di Pescara, Dipartimento di Salute Mentale, Centro di Salute Mentale di Pescara, Pescara
Paola Pincini
Affiliation:
Azienda USL di Pescara, Dipartimento di Salute Mentale, Centro di Salute Mentale di Pescara, Pescara
Corresponding
E-mail address:

Summary

Objective – To verify the association between schizophrenic symptoms and multidimensional variables of social functioning and to look for a possible classification based on an empirical classification outcome oriented. Design – Forthy chronic schizophrenic patients, with a diagnosis ascertained through clinical interview and diagnostic criteria were enrolled in the study. Setting – All patients were followed in a State Mental Health center and were assessed in a stabilized phase of illness. Principal outcome measures – Psychopathological assessment was made with PANSS and CGI. Psychosocial assessment was made with Life Skills Profile and Global Functioning Scale. Results – A pervasive correlation among symptoms and psychosocial variables emerged suggesting a unitary concept of behavior related to diagnosis. Factor analysis revealed 2 main components able to explain the 79% of variance. Cluster analysis separated the patients in 3 different groups showing that clinical symptoms are aggregated with specific variables of social functioning. Conclusion – Schizophrenic symptoms and social functioning are organized in a tripartite structure. It suggests the existence of three different syndromes that are outcome oriented, and compatible with an unitary concept of schizophrenia.

Riassunto

Scopo – Verificare l'esistenza di correlazioni fra sintomatologia schizofrenica e variabili multidimensionali del funzionamento sociale e se tali correlazioni possano condurre ad una precisazione classificativa orientata sull'esito attraverso una metodica empirica. Disegno – Quaranta pazienti affetti da schizofrenia cronica con diagnosi accertata clinicamente e attraverso criteri diagnostici sono stati arruolati. SettingI pazienti erano in carico ad un Centro di Salute Mentale ed erano in fase stabilizzata di malattia definita con criteri operativi. Principali misure utilizzate – Per la valutazione psicopatologica è stata utilizzata la Positive And Negative Syndrome Scale e la Clinical Global Impression. Il funzionamento sociale è stato valutato con la Life Skills Profile e la Scala di Valutazione del Funzionamento Globale. Risultati – Esiste una correlazione fra variabili sintomatologiche e psicosociali che suggerisce un costrutto unitario. A tali variabili soggiaciono 2 fattori principali in grado di spiegare il 79% della varianza che consentono di differenziare il campione in tre gruppi sulla base della Cluster analysis. Sia i sintomi positivi che negativi risultano embricati con alcune aspetti del funzionamento sociale, ma non con tutti. Conclusioni – I sintomi e le variabili psicosociali dei pazienti si aggregano in una struttura omogenea tripartitica. Tale dato suggerisce l'esistenza, nell'ambito di un concetto unitario, di una differenziazione sindromica derivabile con criteri empirici e orientata prognosticamente.

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Articles
Copyright
Copyright © Cambridge University Press 2001

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