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Variations in the Virulence of Different Strains of Bacillus diptheriae

Published online by Cambridge University Press:  15 May 2009

J. A. Arkwright
J. A. Arkwright
Affiliation:
(From the Bacteriological Department, Lister Institute)
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The occurrence of non-virulent strains of bacilli, which are indistinguishable except by animal experiment from virulent diphtheria bacilli, makes it especially interesting to investigate the varying pathogenicity of this bacillus. Owing to their complete lack of pathogenicity for laboratory animals, the exact relationship of the non-virulent types of B. diphtheriae to the virulent forms of this organism, cannot yet be considered as settled, although Arkwright (1910) has succeeded in obtaining a slight but very definite development of antitoxin in the blood of a horse immunised with non-virulent strains.

Type
Research Article
Information
Journal of Hygiene , Volume 11 , Issue 3 , October 1911 , pp. 409 - 422
Copyright
Copyright © Cambridge University Press 1911

References

Arkwright, J. A. (1910). On the Production of Antitoxin by the injection of Filtrates of cultures of non-virulent diphtheria bacilli. Journal of Hygiene, IX. 409.Google Scholar
Arkwright, J. A. (1908). Observations on the Bacteriology of an epidemic of Diphtheria in a school. Journal of Hygiene, VIII. 48.Google Scholar
Bardach, J. (1895). Études sur la Diphtérie. Ann. de l'inst. Pasteur, IX. 40.Google Scholar
Cobbett, L. (1901). The result of 950 bacteriological examinations for Diphtheria bacilli during an outbreak of Diphtheria at Cambridge in the Spring of 1901. Journal of Hygiene, I. 235.Google Scholar
Dean, G. (1908). In The Bacteriology of Diphtheria, by Nuttall and Graham-Smith, Cambridge, p. 462.Google Scholar
Graham-Smith, G. S. (1904). A Study of the Virulence of the Diphtheria bacilli isolated from 113 persons, and of 11 Species of Diphtheria-like organisms, together with the Measures taken to check an outbreak of Diphtheria at Cambridge, 1903. Journal of Hygiene, IV. 258.Google Scholar
Graham-Smith, G. S. (1908). In The Bacteriology of Diphtheria, by Nuttall and Graham-Smith, Cambridge, 1908, p. 173.Google Scholar
Madsen, T. (1907). Handbuch der Technik und Methodik der Immunitäts-forschung, I. p. 42.Google Scholar
Martin, L. (1898). Production de la toxine diphtérique. Ann. de l'inst. Pasteur, XII. 26.Google Scholar
Nuttall, G. H. F. and Graham-Smith, G. S. (1908). The Bacteriology of Diphtheria, Cambridge, pp. 174, 177.Google Scholar
Park, W. H. and Williams, A. W. (1896). The Production of Diphtheria Toxin. Journ. of Exper. Medicine, I. 164.Google Scholar
Pennington, M. E. (1907). The Virulence of diphtheria organisms in the throats of well school-children and Diphtheria convalescents. Journ. of Infect. Diseases, IV. 36.Google Scholar
Smith, Th. and Walker, E. (1896). A comparative study of the toxin production of Diphtheria bacilli. 28th Ann. Rept. State Board of Health of Mass., p. 649.Google Scholar