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Trends in rotavirus from 2001 to 2015 in two paediatric hospitals in Atlanta, Georgia

  • B. K. Sederdahl (a1) (a2), J. Yi (a1), R. C. Jerris (a1) (a3) (a4), S. E. Gillespie (a1), L. F. Westblade (a3) (a4), C. S. Kraft (a3) (a5), A. L. Shane (a1) (a2) (a4) and E. J. Anderson (a1) (a5)...

Abstract

We compared rotavirus detection patterns before (2001–2006) and after (2008–2015) rotavirus vaccine introduction. We also compared rotavirus detection patterns in odd (2009, 2011, 2013, 2015) and even (2008, 2010, 2012, 2014) years post-vaccine separately. Results of stool rotavirus antigen testing from inpatient, outpatient and emergency department encounters from July 2000 to July 2015 at two paediatric hospital laboratories in Atlanta, Georgia were reviewed. Post-vaccine, rotavirus detection declined (30.2% vs. 13.7% (overall 54.6% decline, P <0.001)), occurred more frequently outside the rotavirus season (19.8% vs. 3.5%; P < 0.001), and was more common among older children (26 vs. 13 median months of age; P < 0.001). During odd years post-vaccine, rotavirus detection was significantly higher than even years (20.2% vs. 6.4%; P < 0.001). Rotavirus detection declined substantially and developed a biennial pattern in the post-vaccine era. The intensity and temporality of rotavirus detection in odd years post-vaccine resembled that observed pre-vaccine, although considerably reduced in magnitude.

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Copyright

Corresponding author

Author for correspondence: Evan J. Anderson, MD, E-mail: evanderson@emory.edu

References

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1. Leshem, E, et al. (2015) Acute gastroenteritis hospitalizations among US children following implementation of the rotavirus vaccine. Journal of the American Medical Association 313(22), 22822284.
2. Hill, HA, et al. (2015) National, state, and selected local area vaccination coverage Among children aged 19–35 months – United States, 2014. Morbidity and Mortality Weekly Report 64(33), 889896.
3. Desai, R, et al. (2012) All-cause gastroenteritis and rotavirus-coded hospitalizations among US children, 2000–2009. Clinical Infectious Diseases 55(4), e28e34.
4. Tate, JE, et al. (2013) Trends in national rotavirus activity before and after introduction of rotavirus vaccine into the national immunization program in the United States, 2000 to 2012. The Pediatric Infectious Disease Journal 32(7), 741744.
5. Elam-Evans, LD, Yankey, D, Singleton, JA and Kolasa, M, Centers for Disease C, Prevention (2014) National, state, and selected local area vaccination coverage among children aged 19–35 months – United States, 2013. Morbidity and Mortality Weekly Report 63(34), 741748.
6. Panozzo, CA, Stockman, LJ, Curns, AT and Anderson, LJ (2010) Use of respiratory syncytial virus surveillance data to optimize the timing of immunoprophylaxis. Pediatrics 126(1), e116e123.
7. Gastanaduy, PA, Curns, AT, Parashar, UD and Lopman, BA (2013) Gastroenteritis hospitalizations in older children and adults in the United States before and after implementation of infant rotavirus vaccination. Journal of the American Medical Association 310(8), 851853.
8. Payne, DC, et al. (2011) Direct and indirect effects of rotavirus vaccination upon childhood hospitalizations in 3 US counties, 2006–2009. Clinical Infectious Diseases 53(3), 245253.
9. Hungerford, D, et al. (2016) Early impact of rotavirus vaccination in a large paediatric hospital in the UK. Journal of Hospital Infection 93(2), 117120.
10. Fletcher, S, et al. (2015) Descriptive epidemiology of infectious gastrointestinal illnesses in Sydney, Australia, 2007–2010. Western Pacific Surveillance Response Journal 6(4), 716.
11. Tate, JE, et al. (2013) Comparison of 2 assays for diagnosing rotavirus and evaluating vaccine effectiveness in children with gastroenteritis. Emerging Infectious Diseases 19(8), 12451252.
12. Rota Test: SA Scientific Inc. [cited 2014 11 December]. Available from: http://www.sascientific.com.
13. Remel X/pect Rotavirus: Thermo Scientific [cited 2014 11 December]. Available from: http://www.remel.com.
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Trends in rotavirus from 2001 to 2015 in two paediatric hospitals in Atlanta, Georgia

  • B. K. Sederdahl (a1) (a2), J. Yi (a1), R. C. Jerris (a1) (a3) (a4), S. E. Gillespie (a1), L. F. Westblade (a3) (a4), C. S. Kraft (a3) (a5), A. L. Shane (a1) (a2) (a4) and E. J. Anderson (a1) (a5)...

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