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Transmission of infectious drug resistance from animals to man

  • D. M. Wells (a1) and O. B. James (a1)

Summary

The antibiotic resistance patterns of coliforms in faecal specimens from pigs and their human contacts were studied. The ability of the resistant coliforms to transfer their resistance in vitro to antibiotic-sensitive recipients was examined. The results showed that pigs which had received antibiotics carried more multiply-resistant, R-factor bearing coliforms than pigs which had not been given antibiotics. Human contacts of the antibiotic-treated pigs had a higher incidence of antibiotic-resistant coliforms with R-factors than human contacts of pigs which had not been given antibiotics. It is concluded that antibiotic treatment of farm, animals may lead to acquisition of antibiotic resistance by gut coliforms of man.

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References

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Anderson, E. S. & Lewis, M. J. (1965 a). Drug resistance and its transfer. Nature, Lond. 206, 579–83.
Anderson, E. S. & Lewis, M. J. (1965 b). Characterisation of a transfer factor associated with drug transfer in Salmonella typhimurium. Nature, Lond. 208, 9.
Anderson, E. S. (1968). The ecology of transferable drug resistance in the Enterobacteria. Annual Review of Microbiology, 22, 131–80.
Bauer, A. W., Kirby, W. M. M., Sherris, J. C. & Turck, M. (1966). Antibiotic sensitivity testing by a standardized single disc method. American Journal of Clinical Pathology 45, 493–6.
Datta, N. (1962). Transmissible drug resistance in an epidemic strain of Salmonella typhimurium. Journal of Hygiene 60, 301–10.
Falkow, S., Citarella, J. A., Wohlheiter, J. A. & Watanabe, T. (1966). The molecular nature of R-factors. Journal of Molecular Biology 17, 102–16.
Mann, P. G. & Gebedou, M. (1966). Infectious transfer of drug resistance between intestinal bacteria. Ethiopian Medical Journal 4, 181–8.
Maré, I. J. & Coetzee, J. N. (1965). The isolation of Enterobacteriaceae possessing the property of transmissible multiple-drug resistance. South African Medical Journal 39, 864–5.
Moorehouse, E. C., O'Grady, M. F. & O'Connor, H. (1969). Isolation from sausages of antibiotic-resistant Escherichia coli with R-factors. Lancet ii, 50–2.
Ochiai, K., Yamanaxa, T., Kimura, K. & Sawada, O. (1959). Nippon Iji Shimpo 1861, 34–46. Quoted by Watanabe T. (1963). Infective heredity of multiple drug resistance in bacteria. Bacteriological Reviews 27, 87115.
Schroeder, S., Terry, P. & Bennett, J. V. (1968). Antibiotic resistance and transfer factor in Salmonella, United States, 1967. Journal of the American Medical Association 205, 903–6.
Smith, H. W. (1966). The incidence of infective drug resistance in strains of Escherichia coli isolated from diseased human beings and domestic animals. Journal of Hygiene 64, 465–74.
Smith, H. W. (1969 a). Transfer of antibiotic resistance from animal and human strains of Escherichia coli in the alimentary tract of man. Veterinary Record 85, 31–3.
Smith, H. W. (1969 b). Transfer of antibiotic resistance from animal and human strains of Escherichia coli in the alimentary tract of man. Lancet i, 1174–6.
Walton, J. R. (1966). Infectious drug resistance in Escherichia coli isolated from healthy farm animals. Lancet ii, 1300–2.

Transmission of infectious drug resistance from animals to man

  • D. M. Wells (a1) and O. B. James (a1)

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