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A survey of enteroviruses and adenoviruses in the faeces of normal children aged 0–4 years: A report of the Public Health Laboratory Service and the Society of Medical Officers of Health*

Published online by Cambridge University Press:  15 May 2009

N. S. Galbraith
N. S. Galbraith
Affiliation:
Epidemiological Research Laboratory, Central Public Health Laboratory, London, N. W. 9
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In a survey of enterovirus and adenovirus excretion in normal children in 1961–62, 25,600 faecal specimens were examined, 25,589 of them in cell culture and 17,596 in newborn mice.

Polioviruses were isolated from 156 (0·86%) specimens before Sabin vaccination was introduced in February 1962 and from 389 (5·27%) specimens after this. Coxsackie A viruses were isolated from 894 (5·08%) specimens, Coxsackie B viruses from 196 (0·77%), echoviruses from 278 (1·09%) and adenoviruses from 128 (0·50%).

The isolation rates of these viruses varied with sex, age, geographical area, type of local authority area and season.

The isolation rate of polioviruses before the introduction of Sabin vaccination was the same as in a previous survey carried out in 1957–58, although the rate was lower in Salk vaccinated children than in unvaccinated children. After Sabin vaccination began the isolation rate increased and Type 3 virus replaced Type 1 virus as the most prevalent virus type.

Type
Research Article
Information
Journal of Hygiene , Volume 63 , Issue 4 , December 1965 , pp. 441 - 455
Copyright
Copyright © Cambridge University Press 1965

References

Cole, R. M., Bell, J. A., Beeman, E. A. & Huebner, R. J. (1951). Studies of Coxsackie viruses. Observations on epidemiological aspects of group A viruses. Am. J. publ. Hlth, 41, 1342.CrossRefGoogle ScholarPubMed
Dalldorf, G. & Albrecht, R. (1955). Chronologic association of poliomyelitis and Coxsackie virus infections. Proc. natn. Acad. Sci. U.S.A. 41, 978.CrossRefGoogle ScholarPubMed
Dalldorf, G. & Weigand, H. (1958). Poliomvelitis as a complex infection. J. exp. Med. 108, 605.CrossRefGoogle Scholar
Dane, D. S. (1964). The future of inactivated poliomyelitis vaccines. Proc. R. Soc. Med. 57, 462.Google ScholarPubMed
Dick, G. W. A., Dane, D. S., McAlister, J., Briggs, M., Nelson, R. & Field, C. M. B. (1961). Vaccination against poliomyelitis with live virus vaccines. Effect of previous Salk vaccination on virus excretion. Br. med. J. ii, 266.CrossRefGoogle Scholar
Dömök, I., Molnár, E., Jancsó, A. & Dániel, M. (1962). Enterovirus survey in children after mass vaccination with live attenuated polioviruses. Br. med. J. i, 743.CrossRefGoogle Scholar
Fox, J. P., Gelfand, H. M., LeBlanc, D. R. & Rowan, D. F. (1958). The influence of natural and artificially induced immunity on alimentary infections with polioviruses. Am. J. publ. Hlth, 48, 1181.CrossRefGoogle ScholarPubMed
Galbraith, N. S. (1963). Poliomyelitis surveillance in England and Wales 1962. Proceedings of the 9th Symposium of the European Association against Poliomyelitis and Allied Diseases,Stockholm,September 1963.Google Scholar
Galbraith, N. S. (1964). A survey of poliovirus excretion in normal children. England and Wales 1961–1962. Proceedings of the 10th Symposium of the European Association against Poliomyelitis and Allied Diseases,Warsaw,October 1964.Google Scholar
Gamble, D. R. (1962). Isolation of Coxsackie viruses from normal children aged 0–5 years. Br. med. J. i, 16.CrossRefGoogle Scholar
Gard, S. (1961). Exit poliomyelitis—what next. Yale J. Biol. Med. 34, 277.Google ScholarPubMed
Gard, S. (1964). Proceedings of the 10th Symposium of the European Association against Poliomyelitis and Allied Diseases,Warsaw,October 1964.Google Scholar
Gelfand, H. M. (1959). The incidence of certain endemic enteric virus infections in Southern Louisiana. Sth. med. J., Nashville, 52, 819.CrossRefGoogle ScholarPubMed
Gelfand, H. M. (1961). The occurrence in nature of the Coxsackie and ECHO viruses. Prog, med. Virol. 3, 193.Google ScholarPubMed
Gelfand, H. M., Holguin, A. H., Marchetti, G. E. & Feorino, P. M. (1963). A continuing surveillance of enterovirus infections in healthy children in six United States cities. Viruses isolated during 1960 and 1961. Am. J. Hyg. 78, 358.Google ScholarPubMed
Henry, J. L., Jaikaran, E. S., da vies, J. R., Tomlinson, A. J. H., Mason, P. J., Barnes, J. M. & Beale, A. J. (1963). The responses of infants to quadruple vaccine administered at two, three and four months assessed by antibody titre and challenge with attenuated type 1 virus. Proceedings of the 9th Symposium of the European Association against Poliomyelitis and Allied Diseases,Stockholm,September 1963.Google Scholar
Honig, E. I., Melnick, J. L., Isaoson, P., Parr, R., Myers, I. L. & Walton, M. (1956). An endemiological study of enteric virus infections. Poliomyelitis, Coxsackie and orphan (ECHO) viruses isolated from normal children in two socio-economic groups. J. exp. Med. 103, 247.CrossRefGoogle Scholar
Howe, H. A. (1962). The quantitation of poliomyelitis virus in the human alimentary tract with reference to co-existing levels of homologous serum neutralizing antibody. Am. J. Hyg. 75, 1.Google Scholar
Marine, W. M., Chin, T. D. Y. & Gravelle, C. R. (1962). Limitation of fecal and pharyngeal poliovirus excretion in Salk-vaccinated children. A family study during a type 1 poliomyelitis epidemic. Am. J. Hyg. 76, 173.Google ScholarPubMed
Meers, P. D. (1965). Paralysis after oral poliomyelitis vaccine. A complex infection. Jl R. Army med. Cps, 111, 62.Google Scholar
Melnick, J. L., Walton, M., Isacson, P. & Cardwell, W. (1957). Environmental studies of endemic enteric virus infections. Community seroimmune patterns and poliovirus infection rates. Am. J. Hyg. 65, 1.Google ScholarPubMed
Peckham, C. S. (1964). Echo virus infections in England and Wales 1959–63. Mon. Bull. Minist. Hlih, 23, 217.Google ScholarPubMed
Pereira, H. G. (1959). Adenoviruses. Br. med. Bull. 15, 225.CrossRefGoogle ScholarPubMed
Perkins, F. T., Yetts, R. & Gaisford, W. (1963). Response of 3-months-old infants to 3 doses of trivalent oral poliomyelitis vaccine. Br. med. J. i, 1573.CrossRefGoogle Scholar
Report (1958). The incidence of poliomyelitis virus in normal children under 5 years. Mon. Bull. Minist. Hlth, 17, 231.Google Scholar
Report (1961). Rep. Minist. Hlth, Lond., Part II, 44.Google Scholar
Report (1962). Comparative trial of British and American oral poliomyelitis vaccines. Br. med. J. ii, 142.Google Scholar
Spicer, C. C. (1961). The incidence of poliomyelitis virus in normal children aged 0–5 years. J. Hyg., Camb., 59, 143.CrossRefGoogle ScholarPubMed
Stickle, G. (1964). Observed and expected poliomyelitis in the United States, 1958–1961. Am. J. publ. Hlth, 54, 1222.CrossRefGoogle ScholarPubMed
Vernon, E. (1964). Coxsackie virus infections in the United Kingdom 1958–1962. Mon. Bull. Minist. Hlth, 23, 210.Google ScholarPubMed
ŽÁček, K., Adam, E., Adamová, V., Burian, V., ŘezÁčovÁ, D., SkřìdlovskÁ, E., Vaněč-kovÁ, N. & Vonka, V. (1962). Mass oral (Sabin) poliomyelitis vaccination. Virological and serological surveillance in Czechoslovakia, 1958–9 and 1960. Br. med. J. i, 1091.Google Scholar