Hostname: page-component-848d4c4894-8bljj Total loading time: 0 Render date: 2024-06-29T08:23:30.012Z Has data issue: false hasContentIssue false
  • English
  • Français

The serum opacity reaction of Streptococcus pyogenes: frequency of production of streptococcal lipoproteinase by strains of different serological types and the relationship to M protein production*

Published online by Cambridge University Press:  15 May 2009

Franklin H. Top Jr  and
Lewis W. Wannamaker
Franklin H. Top Jr
Affiliation:
Departments of Pediatrics and Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota, U.S.A.
Lewis W. Wannamaker
Affiliation:
Departments of Pediatrics and Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota, U.S.A.
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The serum opacity reaction (SOR) is produced by some streptococci of group A, but not by streptococci of groups B, C, D, F and G. The production of this reaction was found to be closely related to serotype as determined by M and T antigens. The SOR of an individual strain was found to be consistently stable over a period of time both in strains maintained in the laboratory and in strains isolated sequentially from individual patients following streptococcal infections. Strains for which the demonstration of an M-antigen by the precipitin method was difficult or impossible in general produced a SOR, while strains more easily typable generally failed to produce this reaction. Laboratory selected variants of type 12 strains showed an inverse relationship between M protein and lipoproteinase production, whereas M positive and M negative variants of other serotypes showed no variability with respect to lipoproteinase production.

Type
Research Article
Information
Journal of Hygiene , Volume 66 , Issue 1 , March 1968 , pp. 49 - 58
Copyright
Copyright © Cambridge University Press 1968

References

REFERENCES

Anthony, B. F., Perlman, L. V. & Wannamaker, L. W. (1967). Skin infections and acute nephritis in American Indian children. Pediatrics, Springfield 39, 263.CrossRefGoogle ScholarPubMed
Gooder, H. (1961). Association of a serum opacity reaction with serological type in. Streptococcus pyogenes. J. gen. Microbiol. 25, 347.CrossRefGoogle ScholarPubMed
Hill, M. J. & Wannamaker, L. W. (1968). The serum opacity reaction of Streptococcus pyogenes: general properties of the streptococcal factor and of the reaction in aged serum. J. Hyg., Camb. 66, 37.CrossRefGoogle ScholarPubMed
Köhler, W. (1963). Serum-Opazitäts-Reaktion (SOR) und die Bildung des M-antigens durch Streptococcus pyogenes. Zentbl. Bakt. ParasitKde. Abt. 1, Orig. 189, 275.Google Scholar
Krumwiede, E. (1954). Studies on a lipoproteinase of group A streptococci. J. exp. Med. 100, 629.CrossRefGoogle ScholarPubMed
Lancefield, R. C. (1957). Differentiation of group A streptococci with a common R antigen into three serological types with special reference to the bactericidal test. J. exp. Med. 106, 525.CrossRefGoogle Scholar
Maxted, W. R. (1956). The indirect bactericidal test as a means of identifying antibody to the M antigen of Streptococcus pyogenes. Br. J. exp. Path. 37, 415.Google Scholar
Rowen, R. & Martin, J. (1963). Enhancement of cholesterol esteriflcation in serum by an extract of a group A streptococcus. Biochim. biophys. Acta 70, 396.CrossRefGoogle Scholar
Swift, H. F., Wilson, A. T. & Lancefield, R. C. (1943). Typing of group A hemolytic streptococci by M precipitin reactions in capillary pipettes. J. exp. Med. 78, 127.CrossRefGoogle Scholar
Top, F. H. Jr., Wannamaker, L. W., Maxted, W. R. & Anthony, B. F. (1967). M antigens among group A streptococci isolated from skin lesions. J. exp. Med. 126, 667.CrossRefGoogle Scholar
Ward, H. K. & Rudd, G. V. (1938). Studies on haemolytic streptococci from human sources. Aust. J. exp. Biol. med. Sci. 16, 181.CrossRefGoogle Scholar
Williams, R. E. O. (1958). Laboratory diagnosis of streptococcal infections. Bull. Wld Hlth Org. 19, 153.Google ScholarPubMed
Williams, R. E. O. & Maxted, W. R. (1953). The type classification of Streptococcus pyogenes. Sixth Int. Gongr. Microbiol. Roma.Google Scholar