Skip to main content Accessibility help
×
Home

Seroprevalence of leptospirosis in a rural flood prone district of Bangladesh

  • M. G. Morshed (a1), H. Konishi (a1), Y. Terada (a1), Y. Arimitsu (a2) and T. Nakazawa (a1)...

Summary

Leptospirosis is a worldwide zoonotic disease. In the present investigation, a total of 89 human sera from a flood prone district of Bangladesh was screened by a one-point microscapsule agglutination test (MCAT). MCAT-positive and-doubtful sera were further tested by microscopic agglutination test (MAT) against 16 reference serovars of Leptospira interrogans. and the antibody titres determined. In MCAT, 34 sera were positive and 22 were doubtful. Among those positive and doubtful sera. 33 and 20. respectively were tested by MAT. Thirty-four out of 53 MCAT-screened samples were MAT-positive. The titres ranged from 20 to 1600 with antibodies to serovars copenhageni, australis, cynopteri and icterohaemorrhagiae being the most prevalent. Eleven MCAT-positive samples failed to react with any strains used by MAT, suggesting the presence of new or untested serovars. Among the MAT-positive samples, the presence of antibody against two or more serovars was more common than that of a single serovar. The present study suggests that rural people in Bangladesh are at high risk to leptospiral infection.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Seroprevalence of leptospirosis in a rural flood prone district of Bangladesh
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Seroprevalence of leptospirosis in a rural flood prone district of Bangladesh
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Seroprevalence of leptospirosis in a rural flood prone district of Bangladesh
      Available formats
      ×

Copyright

Corresponding author

* Corresponding author and reprints request to: H. Konishi, Department of Microbiology. Yamaguchi University School of Medicine. 1144 Kogushi. Ube. Yamaguchi 755. Japan.

References

Hide All
1.Faine, S. Guidelines for the control of leptospirosis. Geneva: World Health Organisation, 1982: WHO offset publication no. 67.
2.Ratnam, S, Venugopal, K, Kathiravan, V. Evidence of leptospiral infections in human samples in Madras city. Indian J Med Res 1987: 85: 516–18.
3.Venkataraman, KS, Ramkrishna, J, Raghavan, N. Human leptospirosis: a recent study in Madras. India. Trans R Soc Trop Med Hyg 1991; 85: 304.
4.Ahmed, IP. Serological studies on leptospirosis in Pakistan. J Pakistan Med Assoc 1987; 37: 233–6.
5.Chan, OY, Chia, SE, Nadarajah, N, Sng, EH. Leptospirosis risk in public cleansing and sewer workers. Ann Acad Sci 1987: 16: 586–90.
6.Heisey, GB, Nimmanitya, S, Karnchanachetanee, C et al. , Epidemiology and characterisation of Leptospirosis at an urban and provincial site in Thailand. Southeast Asian J Trop Med Public Health 1988: 19: 317–22.
7.Laurena, P, Padre, P, Watt, G, Tuazon, ML, Gray, MR, Laughlin, W. A serologic survey of rice-field leptospirosis in central Luzon, Philippines. Southeast Asian J Trop Med Public Health 1988: 19: 197–9.
8.Seki, M, Sato, T, Arimitsu, Y, Matuhasi, T, Kobayashi, S. One-point method for serological diagnosis of leptospirosis: a microcapsule agglutination test. Epidemiol Infect 1987: 99: 399405.
9.Arimitsu, Y, Matuhasi, T, Kobayashi, T, Sato, T, Cui, JJ. Serodiagnosis of leptospirosis in China by one-point MCA method. Epidemiol Infect 1987; 99: 393–8.
10.Arimitsu, Y, Cui, JJ, Cho, MK et al. Detection of antibodies to human leptospirosis in China. Korea and Italy using one-point microcapsule agglutination test. In: Kobayashi, Y. ed. Proceedings of the Leptospirosis Research Conference 1990. Matsuyama, Japan: Japanese Leptospirosis Research Society. 1991: 141–50.
11.Nuti, M, Arnaddeo, D, Autorino, GL et al. , Seroprevalence of antibodies to Hantaviruses and Leptospires in selected Italian population groups. Eur J Epidemiol 1992; 8: 98102.
12.Galton, MM, Sulzer, CR, Santa, Rosa CA, Fields, MJ. Application of a micro-technique to the agglutination test for leptospirosis antibodies. Appl Microbiol 1965: 13: 81–5.
13.Ahl, AS, Miller, DA, Bartlett, PC. Leptospira serology in small ruminants on St. Croix. U.S. Virgin Islands. Ann NY Acad Sci 1992: 653: 168–71.

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed