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Serodiagnosis of leptospirosis in China by the one-point MCA method

Published online by Cambridge University Press:  19 October 2009

Y. Arimitsu*
Affiliation:
Department of Applied Immunology, National Institute of Health, Tokyo, Japan
T. Matuhasi
Affiliation:
Department of Applied Immunology, National Institute of Health, Tokyo, Japan
S. Kobayashi
Affiliation:
Asaka Research Laboratories, Fuji Photo Film Co. Ltd, Japan
T. Sato
Affiliation:
Department of Research, Japan Lyophilization Laboratories, Tokyo, Japan
J. J. Cui
Affiliation:
Chengdu Institute of Biological Products, China
*
*Correspondence should be addressed to Dr Y. Arimitsu, Department of Applied Immunology, National Institute of Health, Kamiosaki 2-10-35, Shinagawaku, Tokyo 141, Japan.
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Summary

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The one-point MCA method is very simple to perform nnd useful as a screening test in diagnosing leptospirosis in routine clinical laboratories.

The kit, sensitized with six serovars occurring in Japan, was also useful in detecting serum antibodies of patients with leptospirosis in China.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1987

References

REFERENCES

Arimitsu, Y., Kodayasiii, S., Akama, K. & Matuhasi, T. (1982). Development of a simple serological method for diagnosing leptospirosis: a microcapsule agglutination test. Journal of Clinical Microbiology 15, 835841.Google Scholar
Chen, T. (1985). Development and present status of leptospiral vaccine and technology of vaccine production in China. Japanese Journal of Bacteriology 40, 755762.Google ScholarPubMed
Galton, M. M., Sulzer, C. R., Santa Rosa, C. A. & Fields, M. J. (1965). Application of a micro-technique to the agglutination test for leptospirosis antibodies. Applied Microbiology 13, 8185.Google Scholar
Seki, M.Sato, T., Arimitsu, Y., Kobayashi, S. & Matuhasi, T. (1987). One-point method for serological diagnosis of leptospirosis: a microcapsule agglutination test. Epidemiology and Infection 99, 399405.Google Scholar