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Secretor status, smoking and carriage of Neisseria meningitidis

  • C. C. Blackwell (a1), D. M. Weir (a1), V. S. James (a1), W. T. A. Todd (a2), N. Banatvala (a2), A. K. R. Chaudhuri (a2), H. G. Gray (a3), E. J. Thomson (a4) and R. J. Fallon (a5)...

Summary

A survey of ABO blood groups, secretor status and smoking habits among 389 students and staff of a school in which there was an outbreak of meningococcal disease found no difference in the distribution of the ABO blood groups but a significantly higher proportion of non-secretors (37·6%) in the population examined compared with that reported for previous surveys of the neighbouring population in Glasgow (26·2%) (P < 0·0005). There was also a significantly higher proportion of non-secretors among carriers of meningococci (47%) compared with non-carriers (32%). Increased carriage of meningococci among non-secretors might contribute to the increased susceptibility of individuals with this genetic characteristic to meningococcal disease observed in previous studies. Although passive exposure to cigarette smoke has been associated with meningococcal disease, there was no association between passive smoking and carriage. There was, however, a significant association between active smoking and carriage.

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References

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Blackwell, CC, Jonsdottir, K, Hanson, M, et al. Non-secretion of ABO antigens predisposing to infection by Neisseria meningitidis and Streptococcus pneumoniae. Lancet 1986; ii: 284–5.
Blackwell, CC, Jonsdottir, K, Mohammed, I, Weir, DM. Non-secretion of blood group antigens – a genetic factor predisposing to infection by Neisseria meningitidis. In Poolman, JT ed., et al. , Gonococci and meningococci. Dordrecht: Kluwer Academic Publishers, 1988.
Blackwell, CC, Weir, DM, James, VS, Cartwright, KAV, Stuart, JM, Jones, DM. The Stonehouse study: secretor status and carriage of Neisseria species. Epidemiol Infect 1989; 102: 110.
Stuart, JM, Cartwright, KAV, Dawson, AJ, Rickard, J, Noah, ND. Risk factors for meningococcal disease: a case control study in Southwest England. Community Med 1988; 10: 139–46.
Haneberg, B, Tonjum, T, Rodahl, K, Gedde-Dahl, T. Factors preceding the onset of meningcococcal disease with special emphasis on passive smoking, stressful events, physical fitness and general symptoms of ill health. National Inst Public Health Annals 1983; 6: 169–74.
Kaiser, AB, Hennekens, CH, Saslaw, MS, Hayes, PS, Bennett, JV. Sero-epidemiology and chemoprophylaxis of disease due to sulphonamide resistant Neisseria meningitidis in a civilian population. J Infect. Dis 1974; 130: 217–24.
Farries, JS, Dickson, W, Greenwood, E, Malhotra, TR, Abbot, D, Jones, DM. Meningococcal infection in Bolton1971–1975. Lancet 1975; ii: 1821.
Nichol, KP, Cherry, JD. Bacterial-viral interrelations in respiratory infections of children. N Engl J Med 1967; 277: 667–72.
Eichenwald, K, Kotsevalov, O, Fasso, LA. Some effects of viral infection on ariel dissemination of staphylococci and on susceptibility to bacterial colonization. Bacteriol Rev 1961; 25: 274–81.
Krakinski, K, Nilson, JD, Butler, S, Laby, JP, Kusmiesz, H. Possible association of mycoplasma and viral respiratory infections with bacterial meningitis. J Epidemiol 1987; 125: 499508.
Kinane, DF, Blackwell, CC, Brettle, RP, Weir, DM, Winstanley, FP, Elton, RA. Blood group secretor state and susceptibility to recurrent urinary tract infections in women. Br Med J 1982; 285: 79.
MacSween, MP, Syme, UA. ABO blood groups and skin diseases. Brit J Dermatol 1965; 77: 30–4.
Cameron, JM. Blood groups in tumors of salivary tissue. Lancet 1958; i: 239–40.
Mourant, AE, Kopec, A, Domaniewska-Sobszak, K. The distribution of the human blood groups and other polymorphisms, 2nd ed.London:Oxford University Press, 1976.
Stuart, JM, Cartwright, KAV, Jones, DM, et al. An outbreak of meningococcal disease in Stonehouse: planning and execution of a large-scale survey. Epidemiol Infect 1987; 99: 579–89.
Cartwright, KavStuart, JM, Jones, DM, Noah, ND. The Stonehouse survey, nasopharyngeal carriage of meningococci and Neisseria lactamica. Epidemiol Infect 1987; 99: 591601.
Haverkorn, MJ, Goslings, WRO. Streptococci, ABO blood groups and secretor status. Amer J Human Genet 1969; 21: 360–75.
Burford-Mason, AP, Weber, JCP, Willoughby, JMT. Oral carriage of Candida albicans, ABO blood group and secretor status in healthy individuals. J Med Vet Mycol 1988; 26: 4956.
Blackwell, CC, Aly, FZM, Weir, DM, et al. Blood group, secretor status and oral carriage of yeasts among patients with diabetes mellitus.Diabetes Res. In press.
Wald, N, Kiryluk, S, Darby, S, Doll, R, Pike, M, Peto, R. UK smoking statistics. Oxford: Oxford University Press, 1988.
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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