Skip to main content Accessibility help
×
Home

Secretor status, smoking and carriage of Neisseria meningitidis

Published online by Cambridge University Press:  15 May 2009


C. C. Blackwell
Affiliation:
Department of Bacteriology, University of Edinburgh, Edinburgh
D. M. Weir
Affiliation:
Department of Bacteriology, University of Edinburgh, Edinburgh
V. S. James
Affiliation:
Department of Bacteriology, University of Edinburgh, Edinburgh
W. T. A. Todd
Affiliation:
Infectious Diseases Unit, Monklands District General Hospital, Airdrie
N. Banatvala
Affiliation:
Infectious Diseases Unit, Monklands District General Hospital, Airdrie
A. K. R. Chaudhuri
Affiliation:
Infectious Diseases Unit, Monklands District General Hospital, Airdrie
H. G. Gray
Affiliation:
Department of Community Medicine, Monklands Cumbernauld District, Lanarkshire Health Board, Airdrie
E. J. Thomson
Affiliation:
Microbiology Laboratory, Monklands District General Hospital, Airdrie
R. J. Fallon
Affiliation:
Meningococcus (Scotland) Reference Laboratory, Ruchill Hospital, Glasgow

Summary

A survey of ABO blood groups, secretor status and smoking habits among 389 students and staff of a school in which there was an outbreak of meningococcal disease found no difference in the distribution of the ABO blood groups but a significantly higher proportion of non-secretors (37·6%) in the population examined compared with that reported for previous surveys of the neighbouring population in Glasgow (26·2%) (P < 0·0005). There was also a significantly higher proportion of non-secretors among carriers of meningococci (47%) compared with non-carriers (32%). Increased carriage of meningococci among non-secretors might contribute to the increased susceptibility of individuals with this genetic characteristic to meningococcal disease observed in previous studies. Although passive exposure to cigarette smoke has been associated with meningococcal disease, there was no association between passive smoking and carriage. There was, however, a significant association between active smoking and carriage.


Type
Research Article
Copyright
Copyright © Cambridge University Press 1990

References

Blackwell, CC, Jonsdottir, K, Hanson, M, et al. Non-secretion of ABO antigens predisposing to infection by Neisseria meningitidis and Streptococcus pneumoniae. Lancet 1986; ii: 284–5.CrossRefGoogle Scholar
Blackwell, CC, Jonsdottir, K, Mohammed, I, Weir, DM. Non-secretion of blood group antigens – a genetic factor predisposing to infection by Neisseria meningitidis. In Poolman, JT ed., et al. , Gonococci and meningococci. Dordrecht: Kluwer Academic Publishers, 1988.Google Scholar
Blackwell, CC, Weir, DM, James, VS, Cartwright, KAV, Stuart, JM, Jones, DM. The Stonehouse study: secretor status and carriage of Neisseria species. Epidemiol Infect 1989; 102: 110.CrossRefGoogle ScholarPubMed
Stuart, JM, Cartwright, KAV, Dawson, AJ, Rickard, J, Noah, ND. Risk factors for meningococcal disease: a case control study in Southwest England. Community Med 1988; 10: 139–46.Google Scholar
Haneberg, B, Tonjum, T, Rodahl, K, Gedde-Dahl, T. Factors preceding the onset of meningcococcal disease with special emphasis on passive smoking, stressful events, physical fitness and general symptoms of ill health. National Inst Public Health Annals 1983; 6: 169–74.Google Scholar
Kaiser, AB, Hennekens, CH, Saslaw, MS, Hayes, PS, Bennett, JV. Sero-epidemiology and chemoprophylaxis of disease due to sulphonamide resistant Neisseria meningitidis in a civilian population. J Infect. Dis 1974; 130: 217–24.CrossRefGoogle Scholar
Farries, JS, Dickson, W, Greenwood, E, Malhotra, TR, Abbot, D, Jones, DM. Meningococcal infection in Bolton1971–1975. Lancet 1975; ii: 1821.Google Scholar
Nichol, KP, Cherry, JD. Bacterial-viral interrelations in respiratory infections of children. N Engl J Med 1967; 277: 667–72.CrossRefGoogle ScholarPubMed
Eichenwald, K, Kotsevalov, O, Fasso, LA. Some effects of viral infection on ariel dissemination of staphylococci and on susceptibility to bacterial colonization. Bacteriol Rev 1961; 25: 274–81.Google Scholar
Krakinski, K, Nilson, JD, Butler, S, Laby, JP, Kusmiesz, H. Possible association of mycoplasma and viral respiratory infections with bacterial meningitis. J Epidemiol 1987; 125: 499508.CrossRefGoogle Scholar
Kinane, DF, Blackwell, CC, Brettle, RP, Weir, DM, Winstanley, FP, Elton, RA. Blood group secretor state and susceptibility to recurrent urinary tract infections in women. Br Med J 1982; 285: 79.CrossRefGoogle ScholarPubMed
MacSween, MP, Syme, UA. ABO blood groups and skin diseases. Brit J Dermatol 1965; 77: 30–4.CrossRefGoogle ScholarPubMed
Cameron, JM. Blood groups in tumors of salivary tissue. Lancet 1958; i: 239–40.CrossRefGoogle Scholar
Mourant, AE, Kopec, A, Domaniewska-Sobszak, K. The distribution of the human blood groups and other polymorphisms, 2nd ed.London:Oxford University Press, 1976.Google Scholar
Stuart, JM, Cartwright, KAV, Jones, DM, et al. An outbreak of meningococcal disease in Stonehouse: planning and execution of a large-scale survey. Epidemiol Infect 1987; 99: 579–89.CrossRefGoogle ScholarPubMed
Cartwright, KavStuart, JM, Jones, DM, Noah, ND. The Stonehouse survey, nasopharyngeal carriage of meningococci and Neisseria lactamica. Epidemiol Infect 1987; 99: 591601.CrossRefGoogle ScholarPubMed
Haverkorn, MJ, Goslings, WRO. Streptococci, ABO blood groups and secretor status. Amer J Human Genet 1969; 21: 360–75.Google ScholarPubMed
Burford-Mason, AP, Weber, JCP, Willoughby, JMT. Oral carriage of Candida albicans, ABO blood group and secretor status in healthy individuals. J Med Vet Mycol 1988; 26: 4956.CrossRefGoogle Scholar
Blackwell, CC, Aly, FZM, Weir, DM, et al. Blood group, secretor status and oral carriage of yeasts among patients with diabetes mellitus.Diabetes Res. In press.Google Scholar
Wald, N, Kiryluk, S, Darby, S, Doll, R, Pike, M, Peto, R. UK smoking statistics. Oxford: Oxford University Press, 1988.Google Scholar

Full text views

Full text views reflects PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.

Total number of HTML views: 0
Total number of PDF views: 34 *
View data table for this chart

* Views captured on Cambridge Core between September 2016 - 25th November 2020. This data will be updated every 24 hours.

Access
Hostname: page-component-57c975d4c7-2h56n Total loading time: 0.582 Render date: 2020-11-25T21:07:05.035Z Query parameters: { "hasAccess": "1", "openAccess": "0", "isLogged": "0", "lang": "en" } Feature Flags last update: Wed Nov 25 2020 20:35:14 GMT+0000 (Coordinated Universal Time) Feature Flags: { "metrics": true, "metricsAbstractViews": false, "peerReview": true, "crossMark": true, "comments": false, "relatedCommentaries": false, "subject": true, "clr": false, "languageSwitch": false }

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Secretor status, smoking and carriage of Neisseria meningitidis
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Secretor status, smoking and carriage of Neisseria meningitidis
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Secretor status, smoking and carriage of Neisseria meningitidis
Available formats
×
×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *