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The routine serological investigation of cases and contacts of rubella

Published online by Cambridge University Press:  15 May 2009

J. R. Pattison
Affiliation:
Department of Virology, London Hospital Medical College, Turner Street, London E1 2AD
D. S. Dane
Affiliation:
Department of Virology, Middlesex Hospital Medical School, Riding House Street, London W1
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Summary

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The results of testing sera from 111 patients with rubella-like illnesses and 283 contacts of patients with rubella-like illnesses are described. A sensitive haemagglutination-inhibition test was used in conjunction with fractionation of serum proteins when this was indicated. It was concluded that the testing of serum protein fractions for IgM and IgG rubella antibody greatly increased the effectiveness of laboratory diagnosis. Evidence is presented that during the study period subclinical rubella was relatively uncommon in adults and that the accuracy of clinical diagnosis was high.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1975

References

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