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Plasmid-encoded trimethoprim resistance in salmonellas isolated in Britain between 1970 and 1981

  • E. J. Threlfall (a1), Jennifer A. Frost (a1), Hilary C. King (a1) and B. Rowe (a1)

Summary

Trimethoprim resistance was plasmid-encoded in all trimethoprim-resistant Salmonella typhimurium and in the majority of trimethoprim-resistant salmonellas of other serotypes isolated since 1970 from humans and food animals in Britain. In S. typhimurium, non-autotransferring plasmids of compatibility group 3 and autotransferring plasmids of group H2 predominated. The predominance of these plasmid types has resulted from the spread of clones of trimethoprim-resistant strains of phage types 18,170 and 204c. In other salmonellas, a variety of plasmid compatibility groups have been identified. Almost all plasmids which conferred resistance to trimethoprim also coded for sulphonamide resistance.

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References

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Plasmid-encoded trimethoprim resistance in salmonellas isolated in Britain between 1970 and 1981

  • E. J. Threlfall (a1), Jennifer A. Frost (a1), Hilary C. King (a1) and B. Rowe (a1)

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