Skip to main content Accessibility help
×
Home

Performance of a rapid human metapneumovirus antigen test during an outbreak in a long-term care facility

  • N. HAMADA (a1), K. HARA (a1), Y. MATSUO (a2), Y. IMAMURA (a1), T. KASHIWAGI (a1), Y. NAKAZONO (a1), K. GOTOH (a3), Y. OHTSU (a3), E. OHTAKI (a2), T. MOTOHIRO (a2) and H. WATANABE (a1)...

Summary

Using a newly developed rapid test, an outbreak of human metapneumovirus (HMPV) infection in a long-term care facility was detected within only 2 days after the onset of symptoms in a putative index case. The outbreak was almost under control within 8 days mainly by zoning patients, with the exception of two cases of HMPV that were diagnosed 16 and 17 days after the onset of the outbreak. According to an immunological diagnosis as well as the rapid test, it was eventually proven that 18 patients had HMPV infections. We suspected that even asymptomatic residents, who had not been completely separated from the facility population, were a source of infection. That suggested that all asymptomatic residents should be tested and that the separation of the infected patients should be absolute, if an outbreak of HMPV infection is suspected in such a facility.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Performance of a rapid human metapneumovirus antigen test during an outbreak in a long-term care facility
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Performance of a rapid human metapneumovirus antigen test during an outbreak in a long-term care facility
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Performance of a rapid human metapneumovirus antigen test during an outbreak in a long-term care facility
      Available formats
      ×

Copyright

Corresponding author

* Author for correspondence: Dr N. Hamada, Division of Infectious Disease, Department of Infectious Medicine, Kurume University School of Medicine, 67 Asahimachi, Kurume 830–0011, Japan. (Email: nhamada@med.kurume-u.ac.jp)

References

Hide All
1. Cane, PA, et al. Human metapneumovirus in a haematopoietic stem cell transplant recipient with fatal lower respiratory tract disease. Bone Marrow Transplantation 2003; 31: 309310.
2. Honda, H, et al. Outbreak of human metapneumovirus infection in elderly inpatients in Japan. Journal of the American Geriatrics Society 2006; 54: 177180.
3. Liao, RS, Appelgate, DM, Pelz, RK. An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility for the elderly in Oregon. Journal of Clinical Virology 2012; 53: 171173.
4. Thomas, RE, et al. Influenza vaccination for health-care workers who work with elderly people in institutions: a systematic review. Lancet Infectious Diseases 2006; 6: 273279.
5. Medici, MC, et al. An outbreak of norovirus infection in an Italian residential-care facility for the elderly. Clinical Microbiology and Infection 2009; 15: 97100.
6. Matsuzaki, Y, et al. Evaluation of a new rapid antigen test using immunochromatography for detection of human metapneumovirus in comparison with real-time PCR assay. Journal of Clinical Microbiology 2009; 47: 29812984.
7. Takao, S, et al. The first report of an epidemic of human metapneumovirus infection in Japan: clinical and epidemiological study [in Japanese]. Journal of the Japanese Association for Infectious Diseases 2004; 78: 129137.
8. Ebihara, T, et al. Seroprevalence of human metapneumovirus in Japan. Journal of Medical Virology 2003; 70: 281283.
9. Matsuzaki, Y, et al. Human metapneumovirus infection among family members. Epidemiology and Infection 2013; 141: 827832.
10. Schildgen, V, et al. Human metapneumovirus: lessons learned over the first decade. Clinical Microbiology Reviews 2011; 24: 734754.
11. Van den Hoogen, BG. Respiratory tract infection due to human metapneumovirus among elderly patients Clinical Infectious Diseases 2007; 44: 11591160.
12. Te Wierik, MJ, et al. An outbreak of severe respiratory tract infection caused by human metapneumovirus in a residential care facility for elderly in Utrecht, the Netherlands, January to March 2010. Eurosurveillance 2012; 17.

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed