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Laboratory tests of 5-p-chlorophenyl silatrane as a rodenticide*

  • J. H. Greaves (a1), R. Redfern (a1) and H. Tinworth (a1)

Summary

The properties of 5-p-chlorophenyl silatrane as a rodenticide against Rattus norvegicus and Mus musculus were investigated in the laboratory. The high oral toxicity of the compound was confirmed. When the compound was given to laboratory rats and mice by stomach tube at lethal dosages, signs of poisoning were observed within a minute. When caged wild rats and mice were given a choice between plain and poisoned baits the optimum rodenticidal concentration in the bait was about 0.5% for both species, producing 50% mortality in wild rats and 95% mortality in wild mice. The results are discussed in relation to safety in use and the probable effectiveness of the compound as a rodenticide in field conditions.

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Copyright

References

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Beiter, C. B., Schwarcz, M. & Cerbtree, G. (1970). New, single dose rodenticide. Soap and Chemical Specialities 46, 3867.
Bentley, E. W. & Greaves, J. H. (1960). Some properties of fluoroacetamide as a rodenticide. Journal of Hygiene 58, 125–32.
Greaves, J. H. (1966). Some laboratory observations on the toxicity and acceptability of norbormide to wild Rattus norvegicus and on feeding behaviour associated with sublethal dosing. Journal of Hygiene 64, 275–85.
Greaves, J. H. (1971). Resistance to anticoagulants in rodents. Pesticide Science 2, 276–9.
Rennison, B. D. (1974). Field trials of the rodenticide 5-p-chlorophenyl silatrane against wild rats (Rattus norvegicus Berk.). Journal of Hygiene 73, 45–8.
Rennison, B. D., Hammond, L. E. & Jones, G. L. (1968). A comparative trial of norbormide and zinc phosphide against Rattus norvegicus on farms. Journal of Hygiene 66, 147–58.
Rowe, F. P., Swinney, T. & Bradfield, A. (1974). Field trials of the rodenticide 5-p-chlorophenyl silatrane against wild house mice (Mus musculus L.). Journal of Hygiene, 73, 4952.

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