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Laboratory evaluation of bromadiolone as a rodenticide for use against warfarin-resistant and non-resistant rats and mice

Published online by Cambridge University Press:  15 May 2009

R. Redfern  and
J. E. Gill
R. Redfern
Affiliation:
Ministry of Agriculture, Fisheries and Food, Tolworth Laboratory, Hook Rise South, Tolworth, Surbiton, Surrey
J. E. Gill
Affiliation:
Ministry of Agriculture, Fisheries and Food, Tolworth Laboratory, Hook Rise South, Tolworth, Surbiton, Surrey
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Summary

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Laboratory feeding tests were carried out to determine the efficacy of the anticoagulant rodenticide bromadiolone against Rattus norvegicus, R. rattus and Mus musculus. Using 0·005% bromadiolone, complete kills of R. norvegicus and R. rattus not resistant to warfarin were obtained after exposure to the poison for 1 and 5 days respectively. Warfarin-resistant R. norvegicus were all killed in 4 days, and resistant M. musculus in 12 days. In general, the results resembled those obtained with difenacoum. Acceptance of bromadiolone was very good.

Type
Research Article
Information
Journal of Hygiene , Volume 84 , Issue 2 , April 1980 , pp. 263 - 268
Copyright
Copyright © Cambridge University Press 1980

References

REFERENCES

Boyle, C. M. (1960). Case of apparent resistance of Rattus norvegicus Berkenhout to anticoagulant poisons. Nature 188 (4749), 517.CrossRefGoogle Scholar
European and Mediterranean Plant Protection Organization (1975). Guide-lines for the development and biological evaluation of rodenticides. E.P.P.O. Bulletin 5 (1), 49 pp.Google Scholar
Grand, M. (1976). Experimental data on a new anticoagulant raticide: bromadiolone. Phytiatrie–Phytopharmacie 25, 69–88.Google Scholar
Greaves, J. H., Redfern, R. & King, R. E. (1974). Some properties of calciferol as a rodenticide. Journal of Hygiene 73, 341–5.CrossRefGoogle ScholarPubMed
Hadler, M. R., Redfern, R. & Rowe, F. P. (1975). Laboratory evaluation of difenacoum as a rodenticide. Journal of Hygiene 74, 441–8.CrossRefGoogle ScholarPubMed
Lund, M. (1977). New rodenticides against anticoagulant-resistant rats and mice. E.P.P.O. Bulletin 7 (2), 503–8.Google Scholar
Marsh, R. E. (1977). Bromadiolone, a new anticoagulant rodenticide. E.P.P.O. Bulletin 7 (2), 495–502.Google Scholar
Martin, A. D., Steed, L. C.Redfern, R., Gill, J. E. & Huson, L. W. (1979). Warfarin resistance genotype determination in the Norway rat. Laboratory Animals 13, 209–14.CrossRefGoogle ScholarPubMed
Meehan, A. P. (1978). Rodenticidal activity of bromadiolone–a new anticoagulant. Proceedings of the Eighth Vertebrate Pest Conference, Sacramento, 127–37.Google Scholar
Redfern, R. & GILL, J. E. (1978). The development and use of a test to identify resistance to the anticoagulant difenacoum in the Norway rat (Rattus norvegicus). Journal of Hygiene 81, 427–31.CrossRefGoogle Scholar
Redfern, R., Gill, J. E. & Hadler, M. R. (1976). Laboratory evaluation of WBA 8119 as a rodenticide for use against warfarin-resistant and non-resistant rats and mice. Journal of Hygiene 77, 419–26.CrossRefGoogle ScholarPubMed
Rowe, F. P. & Redfern, R. (1965). Toxicity tests on suspected warfarin-resistant house mice (Mus musculus L.). Journal of Hygiene 63, 417–25.CrossRefGoogle ScholarPubMed