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Investigations of Allerton-type herpes virus infection in East African game animals and cattle

Published online by Cambridge University Press:  15 May 2009

W. Plowright  and
D. M. Jessett
W. Plowright
Affiliation:
East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya
D. M. Jessett
Affiliation:
East African Veterinary Research Organization, Muguga, P.O. Kabete, Kenya
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Summary

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Neutralization tests with a strain (BA) of Allerton-type herpes virus, derived from a buffalo (Syncenis caffer) were carried out on 924 sera from 17 species of E. African game animals and on cattle sera from Tanzania (2001), Kenya (792) and Uganda (410).

Buffalo populations throughout E. Africa showed a very high rate of infection, with all animals over 2 years of age serologically positive. Antibody was present in some giraffe, waterbuck and hippopotamus sera and, less frequently, in impala, eland, bushbuck and oryx. Data are provided on the titres of positive samples; the mean titre of buffalo sera increased with age.

Cattle in many localities of N. Tanzania and S. Kenya showed a very high rate of infection, 85–95% of sera from animals more than 2-years old containing antibody; the titres recorded were lower than those in buffaloes. Very high infection rates were also found in Karamoja and Teso (Uganda) and also in some other areas of Kenya, whilst a considerably lower incidence of infection was detected in W. Nile Province of Uganda and in central Tanzania. Differences in infection rates may have been related to herd size and husbandry practices.

It was shown that a wave of infection was probably spreading through cattle in N. Tanzania at about the same time as an outbreak of disease occurred in buffaloes and it is suggested that virus transmission may have been by biting flies.

No clinical signs attributable to the virus were reported in cattle but mouth lesions similar to those recorded in buffaloes, or nasal lesions, could have passed undetected. Allerton-type virus probably produces a range of clinical syndromes in cattle, closely resembling those associated with some herpes viruses in primates but infection is seldom related in the field to either pseudo-lumpy skin disease, mammillitis or stomatitis.

Type
Research Article
Information
Journal of Hygiene , Volume 69 , Issue 2 , June 1971 , pp. 209 - 222
Copyright
Copyright © Cambridge University Press 1971

References

REFERENCES

Alexander, R. A., Plowright, W. & Haig, D. A. (1957). Cytopathogenic agents associated with lumpy-skin disease of cattle. Bulletin of Epizootic Diseases of Africa 5, 489.Google Scholar
Black, P. H., Hartley, J. W. & Rowe, W. P. (1963). Isolation of a cytomegalovirus from African green monkey. Proceedings of the Society for Experimental Biology and Medicine 112, 601.CrossRefGoogle ScholarPubMed
Capstick, P. B. (1959). Lumpy-skin disease—experimental infection. Bulletin of Epizootic Diseases of Africa 7, 51.Google Scholar
Clarkson, M. J., Thorpe, E. & McCarthy, K. (1967). A virus disease of captive vervet monkeys (Cercopithecus aethiops) caused by a new herpes virus. Archiv für die gesamte Virusforschung 22, 219.CrossRefGoogle Scholar
Daniel, M. D., Karpas, A., Melendez, L. V., King, N. W. & Hunt, R. D. (1967). Isolation of Herpes-T virus from a spontaneous disease in squirrel monkeys (Saimiri sciureus). Archiv für die gesamte Virusforschung 22, 324.CrossRefGoogle ScholarPubMed
Derbyshire, J. B. & Haig, D. A. (1969). Isolation of bovine mammillitis virus from skin gangrene of the bovine udder. Veterinary Record 85, 389.CrossRefGoogle ScholarPubMed
Dougherty, R. M. (1964). In Techniques in Experimental Virology. Ed. Harris, R. J. C.. London: Academic Press.Google Scholar
Dulbecco, R. & Vogt, M. (1954). Plaque formation and isolation of pure lines of poliomyelitis viruses. Journal of Experimental Medicine 99, 167.CrossRefGoogle ScholarPubMed
Toit, R. M. du & Weiss, K. E. (1960). Unpublished experiments. Quoted by Weiss, 1963.Google Scholar
Holmes, A. W., Devine, J. A., Nowkowski, E. & Deinhardt, F. (1966). The epidemiology of a herpes virus infection of New World monkeys. Journal of Immunology 96, 668.CrossRefGoogle ScholarPubMed
Huygelen, C., Thienpont, D. & Vandervelden, M. (1960). Isolation of a cytopathogenic agent from skin lesions in cattle. Nature, London 186, 979.CrossRefGoogle Scholar
Keeble, S. A., Christofinis, G. T. & Wood, W. (1958). Natural virus-B infection in rhesus monkeys. Journal of Pathology and Bacteriology 76, 189.CrossRefGoogle ScholarPubMed
Lepper, A. W. D., Haig, D. A. & Wilcox, J. (1969). Cellular pathology of calves experimentally infected with bovine herpes mammillitis virus. Journal of Comparative Pathology 79, 489.CrossRefGoogle ScholarPubMed
MacOwan, K. D. S. (1962). Annual Report 1961 Department of Veterinary Services, Kenya. p. 45. Nairobi: Government Printer.Google Scholar
Malherbe, H. & Harwin, R. (1958). Neurotropic virus in African monkeys. Lancet, ii, 530.CrossRefGoogle Scholar
Malherbe, H., Harwin, R. & Ulrich, M. (1963). The cytopathic effects of vervet monkey viruses. South African Medical Journal 37, 407.Google ScholarPubMed
Martin, W. B. & Gwynne, M. (1968). Antibodies to the group II lumpy-skin disease viruses in the sera of cattle in Kenya. Bulletin of Epizootic Diseases of Africa 16, 217.Google Scholar
Martin, W. B., Hay, D., Crawford, L. V., Bouvier, G. L. Le & Crawford, E. M. (1966). Characteristics of bovine mammillitis virus. Journal of General Microbiology 45, 325.CrossRefGoogle ScholarPubMed
Martin, W. B., James, , Helen, , Lauder, I. M., Murray, M. & Pirie, H. M. (1969). Pathogenesis of bovine mammillitis virus infection in cattle. American Journal of Veterinary Research 30, 2151.Google ScholarPubMed
Martin, W. B., Martin, B., Hay, D. & Lauder, I. M. (1966). Bovine ulcerative mammillitis caused by a herpes virus. Veterinary Record 78, 494.CrossRefGoogle Scholar
Martin, W. B., Martin, B. & Lauder, I. M. (1964). Ulceration of cows' teats caused by a virus. Veterinary Record 76, 15.Google Scholar
Melnick, J. L., Midulla, M., Wimberley, I., Barbera-oro, J. G. & Levy, B. M. (1964). A new member of the herpes virus group isolated from South American marmosets. Journal of Immunology 92, 596.CrossRefGoogle ScholarPubMed
Plowright, W. (1965). Malignant catarrhal fever in East Africa. I. Behaviour of the virus in free-living populations of blue wildebeest (Gorgon taurinus taurinus, Burcell). Research in Veterinary Science 6, 56.CrossRefGoogle Scholar
Plowright, W. (1967). Malignant catarrhal fever in East Africa. III. Neutralising antibody in free-living wildebeest. Research in Veterinary Science 8, 129.CrossRefGoogle Scholar
Plowright, W., Herniman, K. A. J. & Rampton, C. S. (1969). Studies on rinderpest culture vaccine. I. Some factors affecting virus production. Research in Veterinary Science 10, 373.CrossRefGoogle ScholarPubMed
Plowright, W., Laws, R. M. & Rampton, C. S. (1964). Serological evidence for the susceptibility of the hippopotamus (Hippopotamus amphibius Linnaeus) to natural infection with rinderpest virus. Journal of Hygiene 62, 329.CrossRefGoogle ScholarPubMed
Rweyemamu, M. M. (1969). Bovine herpes mammillitis and skin gangrene of the bovine udder. Veterinary Record 85, 697.Google Scholar
Rweyemamu, M. M., Johnson, R. H. & Laubillabd, R. E. (1969). Serological findings in bovine herpes mammillitis. British Veterinary Journal 125, 317.CrossRefGoogle ScholarPubMed
Rweyemamu, M. M., Johnson, R. H. & Tutt, J. B. (1966). Some observations on herpes virus mammillitis of bovine animals. Veterinary Record 79, 810.CrossRefGoogle ScholarPubMed
Schiemann, B., Plowright, W. & Jessett, D. M. To be published.Google Scholar
Weiss, K. E. (1963). Lumpy skin disease; in Emerging Diseases of Animals; pp. 179–201. Food and Agriculture Organization of the United Nations, Rome.Google Scholar