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The Inactivation of Bactericidal and Haemolytic Complement on standing

Published online by Cambridge University Press:  15 May 2009

J. Gordon  and
L. Hoyle
J. Gordon
Affiliation:
From the Department of Pathology and Bacteriology, University of Leeds
L. Hoyle
Affiliation:
From the Department of Pathology and Bacteriology, University of Leeds
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Hecht (1923) states that the haemolytic activity of serum complement disappears on standing, but that the activity can be restored by the addition of heated fresh serum. It has also been shown (Gordon and Wormall, 1928; Gordon, 1930;. Gordon and Carter, 1932) that the bactericidal action of serum involves the activity of a complement similar to haemolytic complement and that inactivation of the latter by dilute ammonia and congo red causes, at the same time, inactivation of the bactericidal complement. The experiments now to be described show that the similarity of the two complements is exhibited once again in the effect of long standing on serum.

Type
Research Article
Information
Journal of Hygiene , Volume 33 , Issue 3 , August 1933 , pp. 411 - 413
Copyright
Copyright © Cambridge University Press 1933

References

Gordon, J. (1930). J. Path. and Bact. 33, 47, 689.CrossRefGoogle Scholar
Gordon, J. and Carter, H. S. (1932). J. Path. and Bact. 35, 549.CrossRefGoogle Scholar
Gordon, J. and Wormall, A. (1928). J. Path. and Bact. 31, 753.CrossRefGoogle Scholar
Hecht, H. (1923). Z. Immun. Forsch. 63, 322.Google Scholar