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Hand-genital transmission of genital warts? An analysis of prevalence data

Published online by Cambridge University Press:  15 May 2009

C. K. Fairley ,
N. J. Gay ,
A. Forbes ,
M. Abramson  and
S. M. Garland
C. K. Fairley*
Affiliation:
The Department of Social and Preventive Medicine, Monash University, Alfred Hospital, Commercial Road, Prahran, Victoria 3181, Australia Immunisation Division, Public Health Laboratory Service Communicable Disease Surveillance Centre, 61 Colindale Avenue, London NW9 5EQ Department of Microbiology, The Royal Women's Hospital, 132 Grattan Street, Carlton, Victoria 3053, Australia
N. J. Gay
Affiliation:
Immunisation Division, Public Health Laboratory Service Communicable Disease Surveillance Centre, 61 Colindale Avenue, London NW9 5EQ
A. Forbes
Affiliation:
The Department of Social and Preventive Medicine, Monash University, Alfred Hospital, Commercial Road, Prahran, Victoria 3181, Australia
M. Abramson
Affiliation:
The Department of Social and Preventive Medicine, Monash University, Alfred Hospital, Commercial Road, Prahran, Victoria 3181, Australia
S. M. Garland
Affiliation:
Department of Microbiology, The Royal Women's Hospital, 132 Grattan Street, Carlton, Victoria 3053, Australia
*
* To whose correspondence and reprint requests should be addressed.
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Summary

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The role of hand-genital transmission in the aetiology of genital warts is unclear. However this route is suggested by a number of observations including the relatively high proportion of genital warts in children which contain HPV types 1–4 (15% for children and 2% for adults). We compared two transmission models; one which assumes that hand-genital transmission occurs and one that it does not, and determined the conditions in which each model can reflect the available prevalence data. Hand-genital transmission provides a simple explanation of the observed differences in the proportions of genital warts containing HPV types 1–4 and 6/11 in children and adults. If hand-genital transmission does not occur, the observed difference could only be explained by an eightfold greater probability of transmission to children of types 1–4 than types 6/11, or by an eightfold greater duration of infection with types 1–4. Our findings provide support for the view that genital warts may be transmitted by hand-genital contact.

Type
Research Article
Information
Epidemiology & Infection , Volume 115 , Issue 1 , August 1995 , pp. 169 - 176
Copyright
Copyright © Cambridge University Press 1995

References

1.Barrett, TJ, Silbar, JD, McGinley, JP. Genital warts - a venereal disease. JAMA 1954; 154: 333–4.CrossRefGoogle ScholarPubMed
2.Oriel, JD. Natural history of genital warts. Br J Vener Dis 1971; 47: 1–13.Google ScholarPubMed
3.Goldenring, JM. Condylomata acuminata in the evaluation of child sexual abuse. Arch Dermatol 1987; 123: 1265–6.CrossRefGoogle ScholarPubMed
4.Neinstein, LS, Goldenring, JM, Carpenter, S. Nonsexual transmission of sexually transmitted diseases: An infrequent occurrence. Pediatrics 1984; 74: 67–76.CrossRefGoogle ScholarPubMed
5.Oriel, JD. Sexually transmitted diseases in children: human papillomavirus infection. Genitourin Med 1992; 62: 80–3.Google Scholar
6.Cohen, BA, Honig, P, Androphy, EJ. Anogenital warts in children. Arch Dermatol 1990; 126: 1575–80.CrossRefGoogle ScholarPubMed
7.Herman-Giddes, ME, Gutman, LT, Berson, NL. Association of co-existing vaginal infections and multiple abusers in female children with genital warts. Sex Transm Dis 1988; 15: 63–7.CrossRefGoogle Scholar
8.de Villiers, EM, Schneider, A, Gross, G, zur Hausen, H. Analysis of benign and malignant urogenital tumours for human papillomavirus infection by labelling cellular DNA. Med Microbiol Immunol 1986; 174: 281–6.CrossRefGoogle ScholarPubMed
9.Androphy, EJ. Human papillomavirus. Arch Dermatol 1989; 125: 683–5.CrossRefGoogle ScholarPubMed
10.Anderson, RM, May, RM. Infectious diseases of humans: dynamics and control. Oxford: Oxford University Press, 1991.CrossRefGoogle Scholar
11.Hethcote, HW, Yorke, JA. Gonorrhea: transmission dynamics and control. Lect Notes Biomath 1984; 56: 1–105.CrossRefGoogle Scholar
12.Jacques, JA, Simon, CP, Koopman, J, Sattenspiel, L, Perry, T. Modelling and analysing HIV transmission: the effect of contact patterns. Math Biosci 1988; 92: 119–99.CrossRefGoogle Scholar
13.Koutsky, LA, Galloway, DA, Holmes, KK. Epidemiology of genital papillomavirus infection. Epidemiol Rev 1988; 10: 122–63.CrossRefGoogle Scholar
14.Padel, AF, Benning, VA, Evans, MF, Quantrill, AM, Fleming, KA. Human papilloma-viruses in anogenital warts in children: typing by in situ hybridization. BMJ 1990; 300: 1491–4.CrossRefGoogle Scholar
15.Gibson, PE, Gardner, SD, Best, SJ. Human papillomavirus types in anogenital warts of children. J Med Virol 1990; 30: 142–5.CrossRefGoogle ScholarPubMed
16.Rock, B, Naghashfar, Z, Barnett, N, Buscema, J, Woodruff, D, Shah, K. Genital tract papillomavirus infection in children. Arch Dermatol 1986; 122: 1129–32.CrossRefGoogle ScholarPubMed
17.Vallejos, H, Del Mistro, A, Kleinhaus, S, Braunstein, JD, Halwer, M, Koss, LG. Characterization of human papillomavirus types in condylomata acuminata in children by in situ hybridization. Lab Invest 1987; 56: 611–5.Google Scholar
18.Hanson, RM, Glasson, M, McCrossin, I, Rogers, M, Rose, B, Thompson, C. Anogenital warts in childhood. Child Abuse Neglect 1989; 13: 225–33.CrossRefGoogle ScholarPubMed
19.Benton, EC, MacKinlay, GA, Barr, BBB, Smith, IW. Characterization of human papillomavirus DNA from genital warts in children. Br J Dermatol 1989; 121 (suppl 34): 36.CrossRefGoogle Scholar
20.Venning, V, Padel, A, Fleming, K. Venereal and non-venereal human papillomavirus types in childhood genital warts. Br J Dermatol 1989; 121 (suppl 34): 35–6.CrossRefGoogle Scholar
21.Oranje, AP, de Waard-van der Spek, FB, Vuzevski, VD, Bilo, RAC. Condylomata acuminata in children. Int J STD AIDS 1990; 1: 250–5.CrossRefGoogle ScholarPubMed
22.Obalek, S, Jablonska, S, Favre, M, Walczak, L, Orth, G. Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts. J Am Acad Dermatol 1990; 23: 205–13.CrossRefGoogle ScholarPubMed
23.Fleming, KA, Venning, V, Evans, M. DNA typing of genital warts and diagnosis of sexual abuse in children. Lancet 1987; ii: 454.CrossRefGoogle Scholar
24.Fierlbeck, G, Rassner, G, Pfister, H. Condylomata acuminata in children - detection of HPV 6/11 and 2. Local therapy with interferon-betahydrogel. Hautarzt 1992; 43: 148–51.Google Scholar
25.East Anglian Branch of the Society of Medical Officers of Health. The incidence of warts and planter warts amongst school children in East Anglia. Med Offic 1955; 94: 55–9.Google Scholar
26.Finkel, ML, Finkel, DJ. Warts among meat handlers. Arch Dermatol 1985; 120: 1314–7.CrossRefGoogle Scholar
27.Rogo, KO, Nyansera, PN. Congenital condylomata acuminata with meconium staining of amniotic fluid and fetal hydrocephalus: case report. East African Med J 1989; 66: 411–3.Google ScholarPubMed
28.Handley, J, Dinsmore, W, Maw, R et al. , Anogenital warts in prepubertal children; sexual abuse or not? Int J STD AIDS 1993; 4: 271–9.CrossRefGoogle ScholarPubMed