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Epidemiology of group B streptococcus in Korean pregnant women

  • B. K. LEE (a1), Y. R. SONG (a1), M. Y. KIM (a2), J. H. YANG (a2), J. H. SHIN (a3), Y. S. SEO (a3), K. Y. OH (a1), H. R. YOON (a4), S. Y. PAI (a5), B. FOXMAN (a6) and M. KI (a5)...

Summary

Between January 2006 and May 2008, 2624 pregnant S. Korean women between 35–37 weeks gestation were screened for group B streptococcus (GBS). Resistance to antimicrobials was tested by disk diffusion and serotype determined using co-agglutination assays and microarray methods. Overall, 8% of pregnant women were colonized. Serotype III was the predominant serotype (43·8%), followed by serotypes V (20·3%), Ia (12·1%), and Ib (9·5%). GBS was frequently resistant to clindamycin (54·0%) and erythromycin (25·6%); 3·7% were resistant to cefazolin. More than three-quarters of serotype V were resistant to clindamycin or erythromycin or both, and 71% of serotype III were resistant to clindamycin but only 12% were resistant to erythromycin. GBS prevalence exceeded earlier reports by one-third. This is the first report of cefazolin resistance in Korea. These results underscore the need to establish screening measures and chemoprophylaxis guidelines regarding GBS infections in Korea.

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Copyright

Corresponding author

*Author for correspondence: Professor M. Ki, Department of Preventive Medicine, Eulji University School of Medicine, 143-5 Yongdu-dong, Jung-gu, Daejeon, 301-832, Korea. (Email: kimoran@eulji.ac.kr)

References

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Baker, C, et al. Selective Broth medium for isolation of group B streptococci. Applied and Environmental Microbiology 1973; 26: 884885.
Yoon, HK, et al. A case of neonatal group B streptococcal meningitis. Journal of Korean Pediatric Society 1984; 27: 10111017.
Wright Lott, J. Neonatal bacterial sepsis. Critical Care Nursing Clinics of North America 2003; 15: 3546.
Fischer, G, et al. From the National Institute of Allergy and Infectious Diseases. Summary of the National Institutes of Health workshop on group B streptococcal infection. Journal of Infectious Diseases 1983; 148: 163166.
Schrag, S, et al. Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC. MMWR Recommendations and Reports 2002; 51: 122.
Uh, Y, et al. Colonization rates and serotypes of group B streptococci isolated from pregnant women in a Korean tertiary hospital. European Journal of Clinical Microbiology & Infectious Diseases 1997; 16: 753756.
Kim, MW, et al. Group B streptococcal colonization rate in Korean pregnant women. Korean Journal of Obstetrics and Gynecology 2006; 49: 337344.
Choi, K, et al. Clinical significance of group B streptococcal infection in pregnant women. Korean Journal of Obstetrics and Gynecology 2002; 45: 811815.
Uh, Y, et al. Correlation of serotypes and genotypes of macrolide-resistant Streptococcus agalactiae. Yonsei Medical Journal 2005; 46: 480483.
DiPersio, L, DiPersio, J. High rates of erythromycin and clindamycin resistance among OBGYN isolates of group B streptococcus. Diagnostic Microbiology and Infectious Disease 2006; 54: 7982.
Shin, Y, et al. Epidemiology of neonatal sepsis in South Korea. Pediatrics International 2009; 51: 225232.
Sinha, A, et al. Epidemiology of neonatal infections: experience during and after hospitalization. Pediatric Infectious Disease Journal 2003; 22: 244251.
Foxman, B, Riley, L. Molecular epidemiology: focus on infection. American Journal of Epidemiology 2001; 153: 11351141.
Borchardt, SM, et al. Comparison of DNA dot blot hybridization and lancefield capillary precipitin methods for group B streptococcal capsular typing. Journal of Clinical Microbiology 2004; 42: 146150.
Zhang, L, et al. Library on a slide for bacterial comparative genomics. BMC Microbiology 2004; 4: 12.
Stoll, B, Schuchat, A. Maternal carriage of group B streptococci in developing countries. Pediatric Infectious Disease Journal 1998; 17: 499503.
Cheng, P, et al. Maternal anxiety about prenatal screening for group B streptococcus disease and impact of positive colonization results. European Journal of Obstetrics and Gynecology 2006; 128: 2933.
Matsubara, K, et al. Prevalence of group B streptococcal type VI capsular IgG antibodies in Japan. European Journal of Clinical Microbiology & Infectious Diseases 2003; 22: 453454.
Trijbels-Smeulders, MA, et al. Neonatal group B streptococcal infection: incidence and strategies for prevention in Europe. Pediatric Infectious Disease Journal 2004; 23: 172173.
Valkenburg-van den Berg, AW, et al. Prevalence of colonisation with group B Streptococci in pregnant women of a multi-ethnic population in The Netherlands. European Journal of Obstetrics & Gynecology and Reproductive Biology 2006; 124: 178183.
Davies, HD, et al. Multilocus sequence typing of serotype III group B streptococcus and correlation with pathogenic potential. Journal of Infectious Diseases 2004; 189: 10971102.
Edwards, MS, Baker, CJ. Group B streptococcal infections in elderly adults. Clinical Infectious Diseases 2005; 41: 839847.
Lachenauer, C, et al. Serotypes VI and VIII predominate among group B streptococci isolated from pregnant Japanese women. Journal of Infectious Diseases 1999; 179: 10301033.
Lee, K, et al. Trends in serotypes and antimicrobial susceptibility of group B streptococci isolated in Korea. Journal of Infection and Chemotherapy 2000; 6: 9397.
Fernandez, M, et al. Antimicrobial susceptibilities of group B streptococci isolated between 1992 and 1996 from patients with bacteremia or meningitis. Antimicrobial Agents and Chemotherapy 1998; 42: 15171519.
Morales, W, et al. Change in antibiotic resistance of group B streptococcus: impact on intrapartum management. American Journal of Obstetrics and Gynecology 1999; 181: 310314.
Uh, Y, et al. Emerging erythromycin resistance among group B streptococci in Korea. European Journal of Clinical Microbiology & Infectious Diseases 2001; 20: 5254.
Berkowitz, K, et al. Antibiotic resistance patterns of group B streptococci in pregnant women. Journal of Clinical Microbiology 1990; 28: 57.
Chohan, L, et al. Patterns of antibiotic resistance among group B streptococcus isolates: 2001–2004. Infectious Diseases in Obstetrics and Gynecology 2006; 2006: 57492.
Morikawa, Y, et al. Prevalence of cefotaxime resistance in group B streptococcus isolates from Osaka, Japan. Journal of Infection and Chemotherapy 2003; 9: 131133.
Manning, SD, et al. Correlates of antibiotic-resistant group B streptococcus isolated from pregnant women. Obstetrics & Gynecology 2003; 101: 7479.
Pettersson, K. Perinatal infection with Group B streptococci. Seminars in Fetal and Neonatal Medicine 2007; 12: 193197.

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