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Epidemiological features of influenza in Canadian adult intensive care unit patients

  • G. TAYLOR (a1), K. ABDESSELAM (a2), L. PELUDE (a2), R. FERNANDES (a2), R. MITCHELL (a2), A. McGEER (a3), C. FRENETTE (a4), K. N. SUH (a5), A. WONG (a6), K. KATZ (a7), K. WILKINSON (a2), T. MERSEREAU (a2), D. GRAVEL (a2) and the Canadian Nosocomial Infection Surveillance Program (CNISP)...

Summary

To identify predictive factors and mortality of patients with influenza admitted to intensive care units (ICU) we carried out a prospective cohort study of patients hospitalized with laboratory-confirmed influenza in adult ICUs in a network of Canadian hospitals between 2006 and 2012. There were 626 influenza-positive patients admitted to ICUs over the six influenza seasons, representing 17·9% of hospitalized influenza patients, 3·1/10 000 hospital admissions. Variability occurred in admission rate and proportion of hospital influenza patients who were admitted to ICUs (proportion range by year: 11·7–29·4%; 21·3% in the 2009–2010 pandemic). In logistic regression models ICU patients were younger during the pandemic and post-pandemic period, and more likely to be obese than hospital non-ICU patients. Influenza B accounted for 14·2% of all ICU cases and had a similar ICU admission rate as influenza A. Influenza-related mortality was 17·8% in ICU patients compared to 2·0% in non-ICU patients.

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Copyright

This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

Corresponding author

* Author for correspondence: Dr G. Taylor, 1-127 Clinical Sciences Building, University of Alberta, Edmonton Canada T6G 2G3. (Email: Geoff.taylor@ualberta.ca)

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Keywords

Epidemiological features of influenza in Canadian adult intensive care unit patients

  • G. TAYLOR (a1), K. ABDESSELAM (a2), L. PELUDE (a2), R. FERNANDES (a2), R. MITCHELL (a2), A. McGEER (a3), C. FRENETTE (a4), K. N. SUH (a5), A. WONG (a6), K. KATZ (a7), K. WILKINSON (a2), T. MERSEREAU (a2), D. GRAVEL (a2) and the Canadian Nosocomial Infection Surveillance Program (CNISP)...

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