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Effectiveness of a multidimensional approach for prevention of ventilator-associated pneumonia in 21 adult intensive-care units from 10 cities in India: findings of the International Nosocomial Infection Control Consortium (INICC)

  • Y. MEHTA (a1), N. JAGGI (a2), V. D. ROSENTHAL (a3), C. RODRIGUES (a4), S. K. TODI (a5), N. SAINI (a6), F. E. UDWADIA (a7), A. KARLEKAR (a8), V. KOTHARI (a9), S. N. MYATRA (a10), M. CHAKRAVARTHY (a11), S. SINGH (a12), A. DWIVEDY (a13), N. SEN (a14) and S. SAHU (a15)...

Summary

We report on the effect of the International Nosocomial Infection Control Consortium's (INICC) multidimensional approach for the reduction of ventilator-associated pneumonia (VAP) in adult patients hospitalized in 21 intensive-care units (ICUs), from 14 hospitals in 10 Indian cities. A quasi-experimental study was conducted, which was divided into baseline and intervention periods. During baseline, prospective surveillance of VAP was performed applying the Centers for Disease Control and Prevention/National Healthcare Safety Network definitions and INICC methods. During intervention, our approach in each ICU included a bundle of interventions, education, outcome and process surveillance, and feedback of VAP rates and performance. Crude stratified rates were calculated, and by using random-effects Poisson regression to allow for clustering by ICU, the incidence rate ratio for each time period compared with the 3-month baseline was determined. The VAP rate was 17·43/1000 mechanical ventilator days during baseline, and 10·81 for intervention, showing a 38% VAP rate reduction (relative risk 0·62, 95% confidence interval 0·5–0·78, P = 0·0001).

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Copyright

Corresponding author

*Author for correspondence: Dr V. D. Rosenthal, Corrientes Ave, no. 4580, Floor 12, Apt D. Buenos Aires, ZIP 1195, Argentina. (Email: victor_rosenthal@inicc.org)

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Members of the INICC are given in the Appendix.

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References

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Keywords

Effectiveness of a multidimensional approach for prevention of ventilator-associated pneumonia in 21 adult intensive-care units from 10 cities in India: findings of the International Nosocomial Infection Control Consortium (INICC)

  • Y. MEHTA (a1), N. JAGGI (a2), V. D. ROSENTHAL (a3), C. RODRIGUES (a4), S. K. TODI (a5), N. SAINI (a6), F. E. UDWADIA (a7), A. KARLEKAR (a8), V. KOTHARI (a9), S. N. MYATRA (a10), M. CHAKRAVARTHY (a11), S. SINGH (a12), A. DWIVEDY (a13), N. SEN (a14) and S. SAHU (a15)...

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