Skip to main content Accessibility help
×
Home

Bacteria–host interactions of Salmonella Paratyphi B dT+ in poultry

  • F. VAN IMMERSEEL (a1), L. MEULEMANS (a1), J. DE BUCK (a1), F. PASMANS (a1), P. VELGE (a2), E. BOTTREAU (a2), F. HAESEBROUCK (a1) and R. DUCATELLE (a1)...

Abstract

In recent years, a dramatic increase in incidence of the dextro-rotatory tartrate-positive variant (dT+) of Salmonella enterica subspecies enterica serovar Paratyphi B has been observed in poultry and poultry products. In the present study the interactions of this bacterium with the host were studied in vivo and in vitro in an attempt to explain the preferential association of this serotype with poultry. The ability of this organism to invade and multiply in chicken intestinal epithelial cells and the intracellular behaviour in chicken macrophages was studied in vitro using chicken cell lines. In vivo challenge experiments in specific pathogen-free chickens were carried out to determine the level of colonization of caeca and internal organs early after experimental infection. An in vivo trial with commercial broiler chickens, using a seeder model, was performed to determine whether S. Paratyphi B dT+ could persist and spread in broilers until slaughter. S. Paratyphi B dT+ invaded and multiplied in the chicken epithelial cell line and survived in a chicken macrophage cell line. The strain used colonized caeca and internal organs of chickens to a high extent 1 week after infection with a low-dose inoculum. Moreover, the strain was efficiently transmitted within a group of broilers and persisted until slaughter. It was concluded that S. Paratyphi B dT+ was well adapted to poultry and therefore it is suggested that specific control measures against this serotype should be considered.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Bacteria–host interactions of Salmonella Paratyphi B dT+ in poultry
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Bacteria–host interactions of Salmonella Paratyphi B dT+ in poultry
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Bacteria–host interactions of Salmonella Paratyphi B dT+ in poultry
      Available formats
      ×

Copyright

Corresponding author

F. Van Immerseel, Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium.

Bacteria–host interactions of Salmonella Paratyphi B dT+ in poultry

  • F. VAN IMMERSEEL (a1), L. MEULEMANS (a1), J. DE BUCK (a1), F. PASMANS (a1), P. VELGE (a2), E. BOTTREAU (a2), F. HAESEBROUCK (a1) and R. DUCATELLE (a1)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed