Bone, RC, et al.
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest
1992; 101: 1644–1655.
Martin, GS, et al.
The epidemiology of sepsis in the United States from 1979 through 2000. New England Journal of Medicine
2003; 348: 1546–1554.
Bochud, PY, et al.
Innate immunogenetics: a tool for exploring new frontiers of host defence. Lancet Infectious Diseases
2007; 7: 531–542.
Mosmann, TR. Properties and functions of interleukin-10. Advances in Immunology
1994; 56: 1–26.
Mosser, DM, Zhang, X. Interleukin-10: new perspectives on an old cytokine. Immunological Reviews
2008; 226: 205–218.
Neidhardt, R, et al.
Relationship of interleukin-10 plasma levels to severity of injury and clinical outcome in injured patients. Journal of Trauma
1997; 42: 863–870.
Maier, B, et al.
Early versus late onset of multiple organ failure is associated with differing patterns of plasma cytokine biomarker expression and outcome after severe trauma. Shock
2007; 28: 668–674.
McDaniel, DO, et al.
Molecular analysis of inflammatory markers in trauma patients at risk of postinjury complications. Journal of Trauma
2007; 63: 147–157.
Westendorp, RG, et al.
Genetic influence on cytokine production and fatal meningococcal disease. Lancet
1997; 349: 170–173.
Stewart, D, et al.
Genetic contribution to the septic response in a mouse model. Shock
2002; 18: 342–347.
Turner, DM, et al.
An investigation of polymorphism in the interleukin-10 gene promoter. European Journal of Immunogenetics
1997; 24: 1–8.
Baier, RJ, Loggins, J, Yanamandra, K. IL-10, IL-6 and CD14 polymorphisms and sepsis outcome in ventilated very low birth weight infants. BMC Medicine
2006; 4: 10.
Schaaf, BM, et al.
Pneumococcal septic shock is associated with the interleukin-10-1082 gene promoter polymorphism. American Journal of Respiratory and Critical Care Medicine
2003; 168: 476–480.
Jin, X, et al.
Association of interleukin-10-1082 G/G genotype with lower mortality of acute respiratory distress syndrome in a Chinese population. Genetic Testing and Molecular Biomarkers
2011; 15: 203–206.
Ouyang, L, et al.
Quantitative analysis of the association between interleukin-10 1082A/G polymorphism and susceptibility to sepsis. Molecular Biology Reports
2013; 40: 4327–4332.
Gu, W, et al.
Clinical relevance of 13 cytokine gene polymorphisms in Chinese major trauma patients. Intensive Care Medicine
2010; 36: 1261–1265.
Zeng, L, et al.
Clinical relevance of the interleukin 10 promoter polymorphisms in Chinese Han patients with major trauma: genetic association studies. Critical Care
2009; 13: R188.
Higgins, JP, et al.
Measuring inconsistency in meta-analyses. British Medical Journal
2003; 327: 557–560.
Egger, M, et al.
Bias in meta-analysis detected by a simple, graphical test. British Medical Journal
1997; 315: 629–634.
Shimada, T, et al.
Outcome prediction in sepsis combined use of genetic polymorphisms – a study in Japanese population. Cytokine
2011; 54: 79–84.
Davis, SM, et al.
The association of innate immune response gene polymorphisms and puerperal group A streptococcal sepsis. American Journal of Obstetrics and Gynecology
2010; 202: e301–308.
Huebinger, RM, et al.
IL-10 polymorphism associated with decreased risk for mortality after burn injury. Journal of Surgical Research
2010; 164: E141–E145.
Nakada, TA, et al.
Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients. Journal of Surgical Research
2005; 129: 322–328.
Balding, J, et al.
Genomic polymorphic profiles in an Irish population with meningococcaemia: is it possible to predict severity and outcome of disease?
Genes and Immunity
2003; 4: 533–540.
Lowe, PR, et al.
Influence of interleukin-10 polymorphisms on interleukin-10 expression and survival in critically ill patients. Critical Care Medicine
2003; 31: 34–38.
Shu, Q, et al.
IL-10 polymorphism is associated with increased incidence of severe sepsis. Chinese Medical Journal
2003; 116: 1756–1759.
Palumbo, AA, et al.
Analysis of IL-6, IL-10 and IL-17 genetic polymorphisms as risk factors for sepsis development in burned patients. Burns
2012; 38: 208–213.
Carregaro, F, et al.
Polymorphisms IL10-819 and TLR-2 are potentially associated with sepsis in Brazilian patients. Memorias do Instituto Oswaldo Cruz
2010; 105: 649–656.
Emonts, M, et al.
Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations. Shock
2010; 34: 17–22.
Abdel, H, et al.
Genetic polymorphisms of IL-6-174 and IL-10-1082 in full term neonates with late onset blood stream infections. Journal of Pediatric Infectious Diseases
2009; 4: 357–365.
McDaniel, DO, et al.
Molecular analysis of inflammatory markers in trauma patients at risk of postinjury complications. Journal of Trauma – Injury, Infection and Critical Care
2007; 63: 147–157.
Garnacho-Montero, J, et al.
Timing of adequate antibiotic therapy is a greater determinant of outcome than are TNF and IL-10 polymorphisms in patients with sepsis. Critical Care
2006; 10: R111.
Stanilova, SA, et al.
Interleukin-10-1082 promoter polymorphism in association with cytokine production and sepsis susceptibility. Intensive Care Medicine
2006; 32: 260–266.
Zhang, DL, et al.
Association of polymorphisms of IL and CD14 genes with acute severe pancreatitis and septic shock. World Journal of Gastroenterology
2005; 11: 4409–4413.
Jaber, BL, et al.
Cytokine gene promoter polymorphisms and mortality in acute renal failure. Cytokine
2004; 25: 212–219.
Treszl, A, et al.
Genetic variants of TNF-(alpha), IL-1(beta), IL-4 receptor (alpha)-chain, IL-6 and IL-10 genes are not risk factors for sepsis in low-birth-weight infants. Biology of the Neonate
2003; 83: 241–245.
Munafo, MR, et al.
Meta-analysis of genetic association studies. Trends in Genetics
2004; 20: 439–444.
Zintzaras, E. Impact of Hardy-Weinberg equilibrium deviation on allele-based risk effect of genetic association studies and meta-analysis. European Journal of Epidemiology
2010; 25: 553–560.
Thakkinstian, A, et al.
A method for meta-analysis of molecular association studies. Statistics in Medicine
2005; 24: 1291–1306.