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Using hypothetical product configurators to measure consumer preferences for nanoparticle size and concentration in sunscreens

  • Amanda S. Barnard (a1), Jordan J. Louviere (a2), Edward Wei (a3) and Leon Zadorin (a4)


Although nanoparticles have been shown to have clear technological advantages, their use in some consumer products remains controversial, particularly where these products come in direct contact with our bodies. There has been much discussion about using metal oxide nanoparticles in sunscreens, and numerous technology assessments aimed at predicting the type, size and concentration of nanoparticles and surface treatments that will be best for consumers. Yet, the optimal configuration is ultimately the one that people actually want and are willing to pay for, but until now consumer preferences have not been included in model predictions. We describe and discuss a proof of concept study in which we design and implement a hypothetical sunscreen product configurator to predict how people tradeoff sun protection factor (SPF), product transparency and potential toxicity from reactive oxygen species (ROS) in configuring their most preferred sunscreen. We also show that preferred nanoparticle sizes and concentrations vary across demographic groups. Our results suggest that while consumers choose to reduce or eliminate potential toxicity when possible, they do not automatically sacrifice high SPF and product transparency to avoid the possibility of toxicity from ROS. We discuss some advantages of using product configurators to study potential product designs and suggest some future research possibilities.

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Balbus, J. M., Maynard, A. D., Colvin, V. L., Castranova, V., Daston, G. P., Denison, R. A., Dreher, K. L., Goering, P. L., Goldberg, A. M. & Kulinowski, K. M. et al. 2007 Meeting report: hazard assessment for nanoparticles-report from an interdisciplinary workshop. Environmental Health Perspectives 115, 16541659.
Barker, P. J. & Branch, A. 2008 The interaction of modern sunscreen formulations with surface coatings. Progress in Organic Coatings 62, 313320.
Barnard, A. S. 2009a How can ab initio simulations address risks in nanotech? Nature Nanotechnology 4, 332335.
Barnard, A. S. 2009b Computational strategies for predicting the risks associated with nanotechnology. Nanoscale 1, 8995.
Barnard, A. S. 2010 One to one comparison of sunscreen efficacy, aesthetics and potential nanotoxicity. Nature Nanotechnology 5, 271274.
Burello, E. & Worth, A. 2011 Computational nanotoxicology: predicting toxicity of nanoparticles. Nature Nanotechnology 6, 138139.
Cutler, A. & Breiman, L. 1994 Archetypal analysis. Technometrics 36 (4), 338347.
Dellaert, G. C. & Stremersch, S. 2005 Marketing mass-customized products: striking a balance between utility and complexity benedict source. Journal of Marketing Research 42 (2), 219227.
Department of Industry, Innovation, Science, Research and Tertiary Education, Australian Government2012 Study of public attitudes towards sunscreens with nano particles.
Dinh, C. T., Nguyen, T. D., Kleitz, F. & Do, T. O. 2009 Shape controlled synthesis of highly crystalline titania nanocrystals. ACS Nano 3, 37373743.
Fiebig, D. G., Keane, M. P., Louviere, J. J. & Wasi, N. 2010 The generalized multinomial logit model: accounting for scale and coefficient heterogeneity. Marketing Science 29 (3), 393421.
Franke, N., Schreier, M. & Kaiser, U. 2010 The ‘I Designed It Myself’ effect in mass customization. Management Science 56 (1), 125140.
Frischknecht, B. D., Eckert, C., Geweke, J. & Louviere, J. J. 2014 A simple method for estimating preference parameters for individuals. International Journal of Research in Marketing 31 (1), 3548.
Hanson, K. M., Gratton, E. & Bardeen, C. J. 2006 Sunscreen enhancement of UV-induced reactive oxygen species in the skin. Free Radical Biology & Medicine 41, 12051212.
Hirakawa, T., Yawata, K. & Nosaka, Y. 2007 Photocatalytic reactivity for O_2 and OH_radical formation in anatase and rutile TiO2 suspension as the effect of H2O2 addition. Applied Catalyst A: General 325, 105111.
Kertesz, Z. S., Szikszai, Z. & Kiss, A. Z.2003–2004 Quality of skin as a barrier to ultrafine particles. Contribution of the IBA Group to the NANODERM EU5 Project.
Lancaster, K. A. 1966 New approach to consumer theory. Journal of Political Economy 74, 132157.
Li, X. L., Peng, Q., Yi, J. X., Wang, X. & Li, Y. 2006 Near monodisperse TiO2 nanoparticles and nanorods. Chemistry - A European Journal 12, 23832391.
Louviere, J. J. 2013 Modeling single individuals: the Journey from Psych Lab to the App Store. In Choice Modelling: The State of the Art and the State of Practice (ed. Hess, S. & Daly, A.). Chapter 1, Edward Elgar Publishers.
Louviere, J. J., Flynn, T. & Marley, A. A. J. 2015 Best-Worst Scaling: Theory, Methods and Applications. Cambridge University Press.
Louviere, J. J., Hensher, D. A. & Swait, J. 2000 Stated Choice Analysis: Methods and Analysis. Cambridge University Press.
Louviere, J. J. & Woodworth, G. G. 1983 Design and analysis of simulated consumer choice or allocation experiments. Journal of Marketing Research 20, 350367.
Magidson, J. & Vermunt, J. K. 2007 Removing the scale factor confound in multinomial logit choice models to obtain better estimates of preference. Sawtooth Software Conference Proceedings. Sawtooth Software, Inc.
Maynard, A. D. & Aitken, R. J. 2007 Assessing exposure to airborne nanomaterials: current abilities and future requirements. Nanotoxicology 1, 2641.
Maynard, A. D., Aitken, R. J., Butz, T., Colvin, V., Donaldson, K., Oberdorster, G., Philbert, M. A., Ryan, J., Seaton, A. & Stone, V. et al. 2006 Safe handling of nanotechnology. Nature 444, 267269.
McCall, M. J. 2011 Environmental, health and safety issues: nanoparticles in the real world. Nature Nanotechnology 6, 613614.
McFadden, D. 1974 Conditional logit analysis of qualitative choice behavior. In Frontiers in Econometrics (ed. Zarembka, P.), pp. 105142. Academic Press.
McFadden, D. & Train, K. 2000 Mixed MNL models for discrete response. Journal of Applied Economics 15, 447470.
Monteiro Riviere, N. A., Wiench, K., Landsiedel, R., Schulte, S., Inman, A. O. & Riviere, J. E. 2011 Safety evaluation of sunscreen formulations containing titanium dioxide and zinc oxide nanoparticles in UVB sunburned skin: an in vitro and in vivo study. Toxicology Science 123, 264280.
Nischwitz, V. & Goenaga Infante, H. 2012 Improved sample preparation and quality control for the characterisation of titanium dioxide nanoparticles in sunscreens using ow field ow fractionation online with inductively coupled plasma mass spectrometry. Journal of Analytical Atomic Spectrometry 27, 10841092.
Osmond, M. J. & McCall, M. J. 2010 Zinc oxide nanoparticles in modern sunscreens: an analysis of potential exposure and hazard. Nanotoxicology 4, 1541.
Puzyn, T., Leszczynska, D. & Leszczynski, J. 2009 Toward the development of ‘nanoQSARs’: advances and challenges. Small 5, 24942509.
Puzyn, T., Rasulev, B., Gajewicz, A., Hu, X., Dasari, T. P., Michalkova, A., Hwang, H. M., Toropov, A., Leszczynska, D. & Leszczynski, J. 2011 Using nanoQSAR to predict the cytotoxicity of metal oxide nanoparticles. Nature Nanotechnolology 6, 175178.
Samontha, A., Shiowatana, J. & Siripinyanond, A. 2011 Particle size characterization of titanium dioxide in sunscreen products using sedimentation field ow fractionation inductively coupled plasma mass spectrometry. Analytical and Bioanalytical Chemistry 399, 973978.
Sayes, C. M., Reed, K. L. & Warheit, D. B. 2011 Nanoparticle toxicology: measurements of pulmonary hazard effects following exposures to nanoparticles. Methods in Molecular Biology 726, 313324.
Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR), European Commission, Health & Consumer Protection Directorate General2005 The appropriateness of existing methodologies to assess the potential risks associated with engineered and adventitious products of nanotechnologies.
Seaton, A., Tran, L., Aitken, R. & Donaldson, K. 2010 Nanoparticles, human health hazard and regulation. Journal of the Royal Society Interface 7, S119S129.
Serpone, N., Salinaro, A. & Emeline, A. 2001 Deleterious effects of sunscreen titanium dioxide nanoparticles on DNA: efforts to limit DNA damage by particle surface modification. SPIE Proceedings 4258, 8698.
Silverman, B. W. 1981 Using kernel density estimates to investigate multimodality. Journal of the Royal Statistical Society. Series B (Methodological) 43 (1), 9799.
Smijs, T. G. & Pavel, S. 2011 Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness. Nanotechnology Science Applications 4, 95112.
Street, D. J. & Burgess, L. 2007 The Construction of Optimal Stated Choice Experiments: Theory and Methods. (Wiley Series in Probability and Statistics, 647) , Wiley.
Therapeutic Good Administration (TGA)2003 Australian regulatory guidelines for OTC medicines.
Tsuji, J. S., Maynard, A. D., Howard, P. C., James, J. T., Lam, C. W., Warheit, D. B. & Santamaria, A. B. 2006 Research strategies for safety evaluation of nanomaterials. Part IV: risk assessment of nanoparticles. Toxicology Science 89, 4250.
Tyner, K. M., Wokovich, A. M., Doub, W. H., Buhse, L. F., Sung, L. P., Watson, S. S. & Sadrieh, N. 2009 Comparing methods for detecting and characterizing metal oxide nanoparticles in unmodified commercial sunscreens. Nanomedicine 4, 145159.
U.S. Food and Drug Administration (FDA)Table A1, Appendix A, EPA/600/R09/057F.
Wiseman, H. & Halliwell, B. 1996 Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochemical Journal 313, 1729.
Wokovich, A., Tyner, K., Doub, W., Sadrieh, N. & Buhse, L. F. 2009 Particle size determination of sunscreens formulated with various forms of titanium dioxide. Drug Development & Industrial Pharmacy 35, 11801189.



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