Hostname: page-component-848d4c4894-tn8tq Total loading time: 0 Render date: 2024-06-19T10:17:28.740Z Has data issue: false hasContentIssue false

Short Clinical Assessments Applicable to Busy Practices

Published online by Cambridge University Press:  07 November 2014

Ziad Nasreddine*
Affiliation:
Dr. Nasreddine is assistant professor at the University of Sherbrooke, and, McGill University, and has developed the Montreal Cognitive Assessment (MoCA)

Extract

Because biomarkers to detect Alzheimer’s disease (AD) have not yet been validated, physicians must rely on clinical assessments. The Research Committee of the American Neuropsychiatric Association recommended that the ideal cognitive screening instrument have the following characteristics: First, it should take <15 minutes to administer by a clinician at any level of training. Second, it should sample all major cognitive domains, including memory, attention/concentration, executive function, visual-spatial skills, language, and orientation. Third, it should be reliable, having adequate test-retest and inter-rater validity. Finally, it should be able to detect cognitive disorders commonly encountered by neuropsychiatrists.

The American Academy of Neurology Practice Parameters from 1994 and 2001 and the Canadian Consensus Guidelines on Dementia from 2007 recommend that physicians screen subjects with suspected dementia or mild cognitive impairment (MCI), since these patients are at increased risk for AD. Currently, there are no data on the utility of screening subjects who are asymptomatic.

The most commonly used brief cognitive tests are the Mini-Mental State Examination (MMSE), according to a survey conducted by the International Psychogeriatric Association (IPA) in 2006, followed by the clock-drawing test, the delayed-word recall, the verbal fluency test, the similarities test, and the trail-making test. Clinicians appraised these assessments as the most effective and easiest to administer (Slide 1).

Type
Research Article
Copyright
Copyright © Cambridge University Press 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Malloy, PF, Cummings, JL, Coffey, CE, et al.Cognitive screening instruments in neuropsychiatry: a report of the Committee on of the American Neuropsychiatric Association. J Neuropsychiatry Clin Neurosci. 1997; 9(2): 189197.Google Scholar
2.Practice parameter for diagnosis and evaluation of dementia. (summary statement). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 1994; 44(11): 22032206.CrossRefGoogle Scholar
3.Petersen, RC, Stevens, JC, Ganguli, M, Tangalos, EG, Cummings, JL, DeKosky, ST. Practice parameter: Early detection of dementia: Mild cognitive impairment (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001; 56(9): 11311132.CrossRefGoogle Scholar
4.Chertkow, H, Nasreddine, Z, Joanette, Y, et al.Mild cognitive impairment and cognitive impairment, no dementia: Part A, concept and diagnosis. Alzheimers Dement. 2007; 3(4): 266282.CrossRefGoogle Scholar
5.Shulman, KI, Herrmann, N, Brodaty, H, et al.IPA survey of brief cognitive screening instruments. Int Psychogeriatr. 2006; 18(2): 281294.Google Scholar
6.Salmon, DP, Lange, KL. Cognitive screening and neuropsychological assessment in early alzheimer’s disease. Clin Geriatr Med. 2001; 17(2): 229254.Google Scholar
7.Lorentz, WJ, Scanlan, JM, Borson, S. Brief screening tests for dementia. Can J Psychiatry. 2002; 47(8): 723733.Google Scholar
8.Brodaty, H, Low, LF, Gibson, L, Burns, K. What is the best dementia screening instrument for general practitioners to use? Am J Geriatr Psychiatry. 2006; 14(5): 391400.Google Scholar
9.Harvan, JR, Cotter, V. An evaluation of dementia screening in the primary care setting. J Am Acad Nurse Pract. 2006; 18(8): 351360.Google Scholar
10.Holsinger, T, Deveau, J, Boustani, M, Williams, JW Jr.Does this patient have dementia? JAMA. 2007; 297(21): 23912404.Google Scholar
11.Woodford, HJ, George, J. Cognitive assessment in the elderly: a review of clinical methods. QJM. 2007; 100(8): 469484.Google Scholar
12.Jacova, C, Kertesz, A, Blair, M, et al.Neuropsychological testing and assessment for dementia. Alzheimers Dement. 2007;4:299317.Google Scholar
13.Kalbe, E, Kessler, J, Calabrese, P, et al.DemTect: a new, sensitive cognitive screening test to support the diagnosis of mild cognitive impairment and early dementia. Int J Geriatr Psychiatry. 2004; 19(2): 136143.CrossRefGoogle ScholarPubMed
14.Nasreddine, ZS, Phillips, NA, Bédirian, V, et al.The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;5(4)3:695699.Google Scholar
15.Ijuin, M, Homma, A, Mimura, M, et al.Validation of the 7-Minute Screen for the Detection of Early-Stage Alzheimer’s Disease. Dement Geriatr Cogn Disord. 2008; 25(3): 248255.Google Scholar
16.Borson, S, Scanlan, JM, Watanabe, J, et al.Simplifying detection of cognitive impairment: comparison of the Mini-Cog and Mini-Mental State Examination in a multiethnic sample. J Am Geriatr Soc. 2005; 53(5):871874.Google Scholar
17.Wilber, ST, Lofgren, SD, Mager, TG, Blanda, M, Gerson, LW. An evaluation of two screening tools for cognitive impairment in older Emergency Department patients. Acad Emerg Med. 2005; 12(7):612616.CrossRefGoogle ScholarPubMed
18.Kuslansky, G, Buschke, H, Katz, M, Sliwinski, M, Lipton, RB. Screening for Alzheimer’s disease: The memory impairment screen versus the conventional three-word memory test. J Am Geriatr Soc. 2002; 50(6): 10861091.Google Scholar
19.Kokmen, E, Naessens, JM, Offord, KP. A short test of mental status: description and preliminary results. Mayo Clin Proc. 1987; 62(4): 281288.Google Scholar
20.Swain, DG, O’Brien, AG, Nightingale, PG. Cognitive assessment in elderly patients admitted to hospital: the relationship between the shortened version of the Abbreviated Mental Test and the Abbreviated Mental Test and Mini-Mental State Examination. Clin Rehabil. 2000; 14(6): 608610.Google Scholar
21.Callahan, CM, Unverzagt, FW, Hui, SL, et al.Six-item screener to identify cognitive impairment among potential subjects for clinical research. Med Care. 2002; 40(9):771–781.Google Scholar
22.Kuslansky, G, Katz, M, Verghese, J, et al.Detecting dementia with the Hopkins Verbal Learning Test and the Mini-Mental State Examination. Arch Clin Neuropsychol. 2004; 19(1): 89104.Google Scholar
23.Brooke, P, Bullock, R. Validation of a 6 item cognitive impairment test with a view to primary care usage. Int J Geriatr Psychiatry. 1999; 14(11): 936940.Google Scholar
24.Nishiwaki, Y, Breeze, E, Smeeth, L, Bulpitt, CJ, Peters, R, Fletcher, AE. Validity of the Clock-Drawing Test as a screening tool for cognitive impairment in the elderly. Am J Epidemiol. 2004; 160(8): 797807.Google Scholar
25.Tang-Wai, DF, Knopman, DS, Geda, YE, et al.Comparison of the short test of mental status and the mini-mental state examination in mild cognitive impairment. Arch Neurol. 2003; 60(12): 17771781.CrossRefGoogle ScholarPubMed
26.Sager, MA, Hermann, BP, La Rue, A, Woodard, JL. Screening for dementia in community-based memory clinics. WMJ. 2006;105(7);7:2529.Google ScholarPubMed
27.Folstein, MF, Folstein, SE, McHugh, PR. ‘Mini-mental state’. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12(3): 189198.CrossRefGoogle Scholar
28.Petersen, RC, Smith, GE, Waring, SC, Ivnik, RJ, Tangalos, EG, Kokmen, E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999; 56(3): 303308.CrossRefGoogle ScholarPubMed
29.Wind, AW, Schellevis, FG, Van Staveren, G, Scholten, RP, Jonker, C, Van Eijk, JT. Limitations of the Mini-Mental State Examination in diagnosing dementia in general practice. Int J Geriatr Psychiatry. 1997; 12(1): 101108.3.0.CO;2-R>CrossRefGoogle ScholarPubMed
30.Godbolt, AK, Cipolotti, L, Watt, H, Fox, NC, Janssen, JC, Rossor, MN. The natural history of Alzheimer disease: a longitudinal presymptomatic and symptomatic study of a familial cohort. Arch Neurol. 2004; 61(11): 17431748.CrossRefGoogle ScholarPubMed
31.Heinik, J, Solomesh, I, Bleich, A, Berkman, P. Are the clock-drawing test and the MMSE combined interchangeable with CAMCOG as a dementia evaluation instrument in a specialized outpatient setting? J Geriatr Psychiatry Neurol. 2003; 16(2): 7479.Google Scholar
32.Montreal Cognitive Assessment. href=http://www.mocatest.org. Accessed May 2008.Google Scholar
33.Hachinski, V, Iadecola, C, Petersen, RC, et al.National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards. Stroke. 2006; 37(9): 22202241.Google Scholar