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Cerebral Ventricular Asymmetry and Ventriculomegaly Interact to Increase Risk for Schizophrenia: A Case Report and Recommendation for Routine Fetal Sonography

  • Elionora Katz, Jessica A. Burket, Stephanie M. Rosse, Richard B. Rosse, Barbara L. Schwartz and Stephen I. Deutsch...

Abstract

A 60-year-old patient with a clinical diagnosis of schizophrenia underwent a magnetic resonance imaging (MRI) scan related to the evaluation of isolated seizures that emerged while medicated with clozapine. Unexpectedly, the MRI scan revealed evidence of asymmetric and enlarged cerebral ventricles that were interpreted as congenital in origin. The presence of both congenital lateral ventricular asymmetry and ventriculomegaly may interact to increase risk of schizophrenia. The history and clinical features, including cognitive testing, of the illustrative patient are presented.

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Corresponding author

Please direct all correspondence to: Stephen I. Deutsch, MD, PhD, Ann Robinson Endowed Chair in Psychiatry, Professor and Chairman, Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, 825 Fairfax Ave, Ste 710, Norfolk, Virginia 23507. Tel: 757-446-5888; E-mail: DeutscSI@EVMS.EDU

References

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Cerebral Ventricular Asymmetry and Ventriculomegaly Interact to Increase Risk for Schizophrenia: A Case Report and Recommendation for Routine Fetal Sonography

  • Elionora Katz, Jessica A. Burket, Stephanie M. Rosse, Richard B. Rosse, Barbara L. Schwartz and Stephen I. Deutsch...

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